Phase 1 Rheumatoid Arthritis (RA) Clinical Trials
14 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–14 of 14 trials
Recruiting
Phase 1
A Study of LY4213663 in Healthy Participants and Participants With Rheumatoid Arthritis
HealthyRheumatoid Arthritis (RA)
Eli Lilly and Company134 enrolled9 locationsNCT07258849
Recruiting
Phase 1Phase 2
Controlling Hyperactive Immunity With Long-lived Lymphocytes
Rheumatoid Arthritis (RA)Autoimmune Rheumatologic DiseaseDiffuse Cutaneous Systemic Sclerosis+1 more
Quell Therapeutics Limited16 enrolled6 locationsNCT07473154
Recruiting
Phase 1Phase 2
A Study to Assess Safety, Cellular Kinetics and Exploratory Efficacy of Rapcabtagene Autoleucel in Rheumatoid Arthritis and Sjogren's Disease
Rheumatoid Arthritis (RA) and Sjögren's Disease (SjD)
Novartis Pharmaceuticals27 enrolled11 locationsNCT07048197
Recruiting
Phase 1
A Study to Evaluate the Safety and Activity of SAR448501/DR-0201 in Patients With Autoimmune Rheumatic Diseases
Rheumatoid Arthritis (RA)Systemic Lupus Erythematosus (SLE)
Sanofi62 enrolled8 locationsNCT06647069
Recruiting
Phase 1
A First-in-human Study of KT501 Administered Subcutaneously to Patients With Rheumatoid Arthritis (RA).
Rheumatoid Arthritis (RA)
Kali Therapeutics, Inc.24 enrolled1 locationNCT07234773
Recruiting
Phase 1
An Open-label Study of Cizutamig in Refractory Seropositive Rheumatoid Arthritis
Rheumatoid Arthritis (RA)
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology28 enrolled1 locationNCT06946199
Recruiting
Phase 1
A Study of F8IL10 Intra-articular Treatment in Rheumatoid Arthritis
Rheumatoid Arthritis (RA)
Philogen S.p.A.42 enrolled2 locationsNCT07245992
Recruiting
Phase 1
A Phase 1 Study of ADI-001 in Rheumatoid Arthritis
Rheumatoid Arthritis (RA)
Adicet Therapeutics25 enrolled1 locationNCT07100873
Recruiting
Phase 1
Safety and Pharmacokinetics of LPX-TI641 in Rheumatoid Arthritis and Psoriatic Arthritis
Psoriatic Arthritis (PsA)Rheumatoid Arthritis (RA)
LAPIX Therapeutics Inc.48 enrolled1 locationNCT06628206
Recruiting
Phase 1
The Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics Study of SHR-3045 in Healthy Subjects
Rheumatoid Arthritis (RA)
Guangdong Hengrui Pharmaceutical Co., Ltd16 enrolled1 locationNCT07200596
Recruiting
Phase 1
Safety, Tolerability, and PK/PD of CIGB-814 in Chinese Health Participants
Rheumatoid Arthritis (RA)
Yi Fang70 enrolled1 locationNCT07182656
Recruiting
Phase 1
A Phase I Study of QLS12010 Capsules: Safety, Tolerability, PK, PD, and Food Effects in Healthy Adults and Moderate to Severe Atopic Dermatitis Patients
Atopic DermatitisRheumatoid Arthritis (RA)Hidradenitis Suppurativa (HS)
Shanghai Qilu Pharmaceutical Research and Development Center LTD102 enrolled1 locationNCT06946641
Recruiting
Phase 1
Phase 1 Study of HBI0101 CAR-T in Refractory B-Cell Autoimmune Diseases
Rheumatoid Arthritis (RA)Systemic Lupus Erythematosus (SLE)Systemic Sclerosis (SSc)+1 more
Polina Stepensky60 enrolled1 locationNCT07085676
Recruiting
Phase 1
A Clinical Study of YTS109 Cell in R/R Autoimmune Diseases
Rheumatoid Arthritis (RA)Systemic Lupus Erythematosus (SLE)Inflammatory Myopathy+5 more
China Immunotech (Beijing) Biotechnology Co., Ltd.12 enrolled1 locationNCT06978647