Phase 2 Sarcoma,Soft Tissue Clinical Trials

13 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 113 of 13 trials

Recruiting
Phase 2

Preoperative IMRT With Anlotinib and Penpulimab for Localized Sarcoma (SPARE-01)

Sarcoma,Soft TissueAnlotinibIntensity Modulated Radiotherapy+3 more
Cancer Institute and Hospital, Chinese Academy of Medical Sciences30 enrolled1 locationNCT05167994
Recruiting
Phase 2

Pemetrexed, Cisplatin With Soft Tissue Sarcoma

Sarcoma,Soft Tissue
Yonsei University164 enrolled1 locationNCT04605770
Recruiting
Phase 1Phase 2

Retifanlimab (Anti-PD-1 Antibody) With Gemcitabine and Docetaxel in Patients With Advanced Soft Tissue Sarcoma

Soft Tissue SarcomaSarcomaSarcoma,Soft Tissue+1 more
Memorial Sloan Kettering Cancer Center98 enrolled1 locationNCT04577014
Recruiting
Phase 2

Metformin Hydrochloride in Combination With Standard of Care Systemic Therapy in Previously Untreated Advanced Unresectable or Metastatic Soft Tissue Sarcoma

Sarcoma,Soft TissueSarcoma Metastatic
Wake Forest University Health Sciences50 enrolled2 locationsNCT07291297
Recruiting
Phase 2

Feasibility of Total Neoadjuvant Treatment With HYPErthermia in Patients With High-risk Extremity and Trunk Soft Tissue Sarcoma (TNT-HYPE)

Sarcoma,Soft Tissue
Swiss Cancer Institute24 enrolled8 locationsNCT06835049
Recruiting
Phase 1Phase 2

Anti-NY-ESO-1 TCR-Gene Engineered Lymphocytes Given by Infusion to Patients With NY-ESO-1 -Expressing Metastatic Cancers

Triple-Negative Breast CancerNon-small Cell Lung CancerMetastatic Cancer+6 more
Hadassah Medical Organization3 enrolled1 locationNCT05296564
Recruiting
Phase 1Phase 2

Sequential Infusion of CD146-Targeted and HER2-Targeted CAR T Cells in Patients With Advanced Sarcomas

SarcomaSarcoma, SynovialSarcoma,Soft Tissue+6 more
Essen Biotech60 enrolled1 locationNCT07066982
Recruiting
Phase 2

Selinexor Plus Gemcitabine in Selected Advanced Soft-tissue Sarcoma (SeliSarc)

Sarcoma,Soft Tissue
Asociación Europea y Latinoamericana SELNET para la Investigación en Sarcomas88 enrolled11 locationsNCT06114004
Recruiting
Phase 2

Brachytherapy (Iodine-125 Seeds) and Fluzoparib Combination Therapy for Advanced Unresectable Soft Tissue Sarcoma

Sarcoma,Soft TissueBrachytherapyPoly(ADP-ribose) Polymerase Inhibitors
Fujun Zhang32 enrolled1 locationNCT05894018
Recruiting
Phase 2

A Study of AdAPT-001 in Subjects With Sarcoma and Refractory Solid Tumors

SarcomaCancerSolid Tumor, Adult+3 more
EpicentRx, Inc.140 enrolled6 locationsNCT04673942
Recruiting
Phase 2

Phase II Clinical Trial of Chidamide Combined With AK112 for Second-line and Advanced Bone and Soft Tissue Sarcoma

SarcomaSarcoma,Soft TissueSarcoma of Bone
Shanxi Province Cancer Hospital30 enrolled1 locationNCT06637007
Recruiting
Phase 2

PARP Inhibition, Stereotactic Body Radiotherapy and Immunotherapy for Metastatic or Advanced Sarcoma (PRIMA)

SarcomaSarcoma,Soft TissueSarcoma of Bone
Ruijin Hospital86 enrolled1 locationNCT06074692
Recruiting
Phase 1Phase 2

Trabectedin Plus Radiotherapy in Soft Tissue Sarcoma Patients

Sarcoma,Soft TissueLeiomyosarcomaLiposarcoma+2 more
Grupo Espanol de Investigacion en Sarcomas199 enrolled17 locationsNCT02275286