Phase 2 SCI Clinical Trials

34 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 34 trials

Recruiting
Phase 1Phase 2

Lentiviral Gene Transfer for Treatment of Children Older Than Two Years of Age With X-Linked Severe Combined Immunodeficiency (XSCID)

X-linked Severe Combined Immunodeficiency (XSCID)
National Institute of Allergy and Infectious Diseases (NIAID)40 enrolled1 locationNCT01306019
Recruiting
Phase 1Phase 2

Double Dose 4-AP on Functional Recovery After Spinal Cord Injury

SCI - Spinal Cord Injury
Shirley Ryan AbilityLab27 enrolled1 locationNCT06853015
Recruiting
Phase 2

Phase II Trial of Ivonescimab in Previously Treated Patients With Advanced Clear Cell Renal Cell Carcinoma

IvonescimabClear Cell Renal Carcinoma
M.D. Anderson Cancer Center40 enrolled1 locationNCT06940518
Recruiting
Phase 2

Phase II Clinical Study of Probiotic LR607 in Patients With Non-Small Cell Lung Cancer

NSCLC Diagnosed by Histology or CytologyA Multidisciplinary Team Assessment Determined That the Patient Was a Suitable Candidate for Radical Surgical ResectionOverall Lung Function is Adequate for the Planned Lung Resection+1 more
Zhujiang Hospital46 enrolled1 locationNCT07534033
Recruiting
Phase 1Phase 2

Intraperitoneal SK-NK Cell Injection for Advanced Ovarian Cancer With Massive Ascites

AscitesOvarian Neoplasms Malignant
Cancer Institute and Hospital, Chinese Academy of Medical Sciences29 enrolled1 locationNCT07435701
Recruiting
Phase 2

Statin and Beta Blocker Use in Patients With Decompensated Cirrhosis

CirrhosisDecompensated Cirrhosis of LiverDecompensated Liver Cirrhosis+1 more
CAMC Health System50 enrolled1 locationNCT06764966
Recruiting
Phase 2

Phase II Randomized-registry Embedded Study of Lymphoscintigraphy for Oropharyngeal Neoplasms to Enable Risk-adapted Nodal Guidance for Robotic Surgery and/or Radiotherapy (LONE-RANGR2)

Oropharyngeal NeoplasmsRobotic Surgery and/or RadiotherapyLymphoscintigraphy
M.D. Anderson Cancer Center240 enrolled1 locationNCT06167291
Recruiting
Phase 1Phase 2

Intraperitoneal Injection of Liposomal Irinotecan as Monotherapy or in Combination With Recombinant Mutant Human Tumor Necrosis Factor or Bevacizumab for the Treatment of Malignant Ascites Following Failure of Prior Standard Therapy

Malignant ascites
Dong sheng Zhang48 enrolled1 locationNCT07397819
Recruiting
Phase 1Phase 2

A Prospective, Multicenter, Phase Ib/II Trial of Ivonescimab (AK112) Combined With Albumin-Paclitaxel and Cisplatin as Neoadjuvant Therapy for ESCC

Esophageal Squamous Cell CarcinomaNeoadjuvantIvonescimab
Tang-Du Hospital45 enrolled1 locationNCT07385001
Recruiting
Phase 2

Ginger Root Extract for Sciatic Pain Individuals

Neuropathic PainSciatic pain
Leslie Shen80 enrolled2 locationsNCT06817018
Recruiting
Phase 1Phase 2

A First-in-Human, Open-Label, Dose-Escalation Study to Evaluate the Safety and Tolerability of Gene Therapy With TTX-381 for the Ocular Manifestations Associated With Neuronal Ceroid Lipofuscinosis Type 2 (CLN2) Disease

Neuronal Ceroid Lipofuscinosis Type 2
Tern Therapeutics, LLC16 enrolled2 locationsNCT05791864
Recruiting
Phase 1Phase 2

Intraperitoneal Immune Checkpoint Inhibitors and Zoledronic Acids for Gastric Cancer Malignant Ascites

Ascites, MalignantCancer of Stomach, Adenocarcinoma
Qilu Hospital of Shandong University24 enrolled1 locationNCT06759064
Recruiting
Phase 2

High Dose Albumin in Refractory Ascites

Ascites
Baylor College of Medicine100 enrolled1 locationNCT05867602
Recruiting
Phase 2

CardioPulmonary Resuscitation With Argon (CPAr) Trial

Cardiac Arrest, Out-Of-HospitalCardiac Arrest With Successful Resuscitation
Mario Negri Institute for Pharmacological Research120 enrolled9 locationsNCT05482945
Recruiting
Phase 1Phase 2

SCID-X1 Gene Therapy Via Intravenous Lentiviral (Ivlv-X1) Injection

SCID, X-Linked
Shenzhen Geno-Immune Medical Institute10 enrolled2 locationsNCT03217617
Recruiting
Phase 1Phase 2

Phase 1b/2a Clinical Trial to Determine the Safety, Tolerability and Efficacy of TZ-161 in Spinal Cord Injury

Acute Spinal Cord Injury (SCI)
Technophage, SA28 enrolled2 locationsNCT06677229
Recruiting
Phase 2Phase 3

Effectiveness of Alternative Therapies in Maintaining Weight Loss Achieved by GLP-1 Medications Post-Cessation

longevityAgingGLP - 1+1 more
AgelessRx150 enrolled1 locationNCT07092618
Recruiting
Phase 1Phase 2

Effects of CBD/CBD-A Oral Extract on Resting-state EEG and Neuropathic Pain Symptoms After SCI

Neuropathic PainSCI - Spinal Cord Injury
University of Miami20 enrolled1 locationNCT05630235
Recruiting
Phase 2Phase 3

Apomorphine in Severe Brain-injured Patients

Disorder of Consciousness
University of Liege48 enrolled4 locationsNCT05213169
Recruiting
Phase 2

Albumin Assisted Diuresis in Patients with Cirrhosis and Ascites

CirrhosisAscites Hepatic
Anahita Rabiee MD MHS20 enrolled1 locationNCT06812390