Phase 4 Sclerosis Clinical Trials
33 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–20 of 33 trials
Recruiting
Phase 4
A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Ocrelizumab in Participants With Relapsing Multiple Sclerosis and Primary Progressive Multiple Sclerosis
Relapsing Multiple SclerosisPrimary Progressive Multiple Sclerosis
Hoffmann-La Roche60 enrolled17 locationsNCT07483450
Recruiting
Phase 4
The Effect of InTensive Statin in Ischemic Stroke With inTracranial Atherosclerotic Plaques
Stroke, IschemicAtherosclerosis, Cerebral
General Hospital of Shenyang Military Region100 enrolled1 locationNCT03753555
Recruiting
Phase 4
Ocrelizumab Discontinuation in Relapsing Multiple Sclerosis
Multiple Sclerosis
National Institute of Allergy and Infectious Diseases (NIAID)123 enrolled12 locationsNCT05285891
Recruiting
Phase 4
Safety and Immunogenicity of the Live Attenuated Tetravalent Butantan-Dengue Vaccine in Autoimmune Rheumatic Diseases
Psoriatic Arthritis (PsA)Rheumatoid Arthritis (RA)Systemic Lupus Erythematosus (SLE)+9 more
University of Sao Paulo General Hospital477 enrolled2 locationsNCT07087912
Recruiting
Phase 4
Safety and Efficacy Study of Fingolimod in Taiwanese Adults (≥ 20years) With Relapsing Remitting Multiple Sclerosis
Multiple Sclerosis
Novartis Pharmaceuticals30 enrolled6 locationsNCT04480853
Recruiting
Phase 4
Ublituximab (Briumvi) for Early Forms of Relapsing Multiple Sclerosis
Multiple SclerosisMultiple Sclerosis (MS) - Relapsing-remitting
Northwestern University40 enrolled1 locationNCT07225361
Recruiting
Phase 4
Sparsentan in Posttransplant Immunoglobulin A Nephropathy or Focal Segmental Glomerulosclerosis
Kidney TransplantFocal Segmental GlomerulosclerosisProteinuria+1 more
Travere Therapeutics, Inc.20 enrolled9 locationsNCT07219121
Recruiting
Phase 4
Dalfampridine Combined With Physical Therapy for Mobility Impairment in Multiple Sclerosis
Multiple Sclerosis
MGH Institute of Health Professions48 enrolled1 locationNCT06136728
Recruiting
Phase 4
Concentration of Ofatumumab in the Breast Milk of Lactating Women With Relapsing Forms of Multiple Sclerosis
Multiple Sclerosis
Novartis Pharmaceuticals20 enrolled22 locationsNCT06444113
Recruiting
Phase 4
A Study to Learn More About the Long-Term Safety of Tofersen (Qalsody) in Chinese Participants With SOD-1 Amyotrophic Lateral Sclerosis (ALS)
Amyotrophic Lateral Sclerosis
Biogen12 enrolled1 locationNCT07223723
Recruiting
Phase 4
Glucose Consumption in MS Using [F-18]FDG-PET
Multiple Sclerosis
Brigham and Women's Hospital50 enrolled1 locationNCT07087106
Recruiting
Phase 4
Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes
AtherosclerosisMetforminPrediabetic State
VA Office of Research and Development7,410 enrolled40 locationsNCT02915198
Recruiting
Phase 4
Individualised Cryoneurolysis to Treat Pain in the Context of Spasticity in the Upper and Lower Extremities
Multiple SclerosisSpinal Cord InjuryCentreal Neurological Condition+1 more
Oxford University Hospitals NHS Trust50 enrolled1 locationNCT07303582
Recruiting
Phase 4
Prospective Evaluation of Sequencing From antiCD-20 Therapies to Ozanimod
Relapsing Multiple Sclerosis
University of Colorado, Denver100 enrolled3 locationsNCT06529406
Recruiting
Phase 4
Comparison of Moderate-Intensity Statin Plus Ezetimibe vs. High-Intensity Statin for Coronary Plaque Stabilization
Coronary Artery DiseasePlaque, AtheroscleroticAtherosclerosis of Coronary Artery
Korea University Anam Hospital408 enrolled1 locationNCT06767345
Recruiting
Phase 4
PCSK9 Inhibitor With Statin Therapy for Asymptomatic Intracranial Atherosclerosis
Atherosclerotic PlaqueIntracranial AtherosclerosisIntracranial Artery Stenosis
Peking Union Medical College Hospital300 enrolled19 locationsNCT06902740
Recruiting
Phase 4
Effects of Ocrelizumab Treatment on Immune Cells in Lymph Nodes in Multiple Sclerosis
Multiple Sclerosis, Relapsing-Remitting
University of California, San Francisco5 enrolled1 locationNCT06495593
Recruiting
Phase 4
Effect of Tirzepatide on Progression of Coronary Atherosclerosis Using MDCT
AtherosclerosisType II Diabetes
Matthew J. Budoff120 enrolled1 locationNCT05708859
Recruiting
Phase 4
The Safety and Efficacy of Telitacicept in the Treatment of Systemic Sclerosis
Systemic Sclerosis
Peking University Third Hospital20 enrolled1 locationNCT06546540
Recruiting
Phase 4
Clopidogrel Versus Cilostazol on Vessels
AtherosclerosisType 2 Diabetes
Seoul National University Bundang Hospital120 enrolled1 locationNCT06402747