Sickle Cell Disease Clinical Trials in Birmingham, Alabama
13 recruitingBirmingham, Alabama
Showing 1–13 of 13 trials
Recruiting
Phase 3
A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)
Sickle Cell Disease
Novartis Pharmaceuticals315 enrolled31 locationsNCT06439082
Recruiting
Phase 3
The Efficacy and Safety of Rilzabrutinib in Participants Aged 10 to 65 Years With Sickle-cell Disease
Sickle Cell Disease
Sanofi192 enrolled54 locationsNCT06975865
Recruiting
Phase 1Phase 2
A Phase I/II Study of ITU512 in Healthy Participants and Patients With Sickle Cell Disease
Sickle Cell Disease
Novartis Pharmaceuticals161 enrolled3 locationsNCT06546670
Recruiting
Phase 3
A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease
Sickle Cell Disease
Novo Nordisk A/S408 enrolled172 locationsNCT06612268
Recruiting
Phase 1
SCD Stem Cell Mobilization and Apheresis Using Motixafortide
Sickle Cell Disease
St. Jude Children's Research Hospital15 enrolled2 locationsNCT06442761
Recruiting
Phase 4
Rollover Study for Patients With Sickle Cell Disease Who Have Completed a Prior Novartis-Sponsored Crizanlizumab Study
Sickle Cell Disease
Novartis Pharmaceuticals130 enrolled30 locationsNCT04657822
Recruiting
Phase 1
A Phase 1b, Open-Label Study of DISC-3405 in Participants With Sickle Cell Disease (SCD)
Sickle Cell Disease
Disc Medicine, Inc24 enrolled3 locationsNCT07187973
Recruiting
Phase 3
A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia
Sickle Cell DiseaseThalassemia
Novo Nordisk A/S480 enrolled103 locationsNCT06609226
Recruiting
Phase 2
Cognitive Remediation Intervention to Prepare for Transition of Care
Cognitive ImpairmentSickle Cell DiseaseSelf Efficacy+3 more
University of Alabama at Birmingham120 enrolled1 locationNCT05336201
Recruiting
Not Applicable
Early Life Exposures Among Children With Sickle Cell Disease
Sickle Cell DiseaseBreastfeedingAdverse Childhood Experiences
University of Alabama at Birmingham20 enrolled1 locationNCT05377372
Recruiting
A Long-term Follow-up Study in Patients Who Received BEAM-101
Sickle Cell DiseaseHemoglobinopathy
Beam Therapeutics Inc.50 enrolled17 locationsNCT07373639
Recruiting
Recruitment and Engagement in Care to Impact Practice Enhancement (RECIPE) for Sickle Cell Disease
Sickle Cell Disease
RTI International500 enrolled9 locationsNCT06385886
Recruiting
Comparing the Effectiveness of Matched Related Donor Hematopoietic Stem Cell Transplantation to Disease Modifying Therapy in Pediatric Patients With Sickle Cell Disease
Sickle Cell Disease (SCD)
University of Rochester480 enrolled37 locationsNCT06941389