Sickle Cell Disease Clinical Trials in Boston, Massachusetts

11 recruitingBoston, Massachusetts

Showing 111 of 11 trials

Recruiting
Phase 1Phase 2

A Phase I/II Study of ITU512 in Healthy Participants and Patients With Sickle Cell Disease

Sickle Cell Disease
Novartis Pharmaceuticals161 enrolled3 locationsNCT06546670
Recruiting
Phase 3

A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease

Sickle Cell Disease
Novo Nordisk A/S408 enrolled172 locationsNCT06612268
Recruiting
Phase 2

A Dose-Finding Study of Tebapivat to Assess Efficacy, and Safety in Participants With Sickle Cell Disease (SCD)

Sickle Cell Disease
Agios Pharmaceuticals, Inc.56 enrolled32 locationsNCT06924970
Recruiting
Phase 3

A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia

Sickle Cell DiseaseThalassemia
Novo Nordisk A/S480 enrolled103 locationsNCT06609226
Recruiting
Phase 1

Hematopoietic Stem Cell BCL11A Enhancer Gene Editing for Severe β-Hemoglobinopathies

Beta-ThalassemiaSickle Cell DiseaseSickle Cell Anemia (HbSS, or HbSβ-thalassemia0)+1 more
Daniel Bauer10 enrolled1 locationNCT06647979
Recruiting

A Long-term Follow-up Study in Patients Who Received BEAM-101

Sickle Cell DiseaseHemoglobinopathy
Beam Therapeutics Inc.50 enrolled17 locationsNCT07373639
Recruiting

ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

ThrombophiliaThrombosisSickle Cell Disease+10 more
American Thrombosis and Hemostasis Network3,000 enrolled71 locationsNCT04398628
Recruiting

A Pilot Study on Neuroimaging in SCD: Part of The Boston Consortium to Cure Sickle Cell Disease

Sickle Cell Disease
Boston Children's Hospital8 enrolled1 locationNCT04166526
Recruiting
Not Applicable

Promoting Resilience Among Adolescents and Young Adults With Sickle Cell Disease

Sickle Cell Disease
Boston Children's Hospital25 enrolled1 locationNCT06555939
Recruiting

Comparing the Effectiveness of Matched Related Donor Hematopoietic Stem Cell Transplantation to Disease Modifying Therapy in Pediatric Patients With Sickle Cell Disease

Sickle Cell Disease (SCD)
University of Rochester480 enrolled37 locationsNCT06941389
Recruiting

Study of the Role of Genetic Modifiers in Hemoglobinopathies

Sickle Cell Disease
Cyprus Institute of Neurology and Genetics30,000 enrolled26 locationsNCT05799118