SLE (Systemic Lupus) Clinical Trials

7 recruiting

SLE (Systemic Lupus) Trials at a Glance

7 actively recruiting trials for sle (systemic lupus) are listed on ClinicalTrialsFinder across 6 cities in 13 countries. The largest study group is Phase 1 with 4 trials, with the heaviest enrollment activity in Sofia, Tbilisi, and Iowa City. Lead sponsors running sle (systemic lupus) studies include Chongqing Precision Biotech Co., Ltd, Cullinan Therapeutics Inc., and CRISPR Therapeutics.

Browse sle (systemic lupus) trials by phase

Treatments under study

About SLE (Systemic Lupus) Clinical Trials

Looking for clinical trials for SLE (Systemic Lupus)? There are currently 7 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new SLE (Systemic Lupus) trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about SLE (Systemic Lupus) clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 17 of 7 trials

Recruiting
Phase 2

A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase 2a Study With an Open-Label Extension Evaluating the Efficacy and Safety of VENT-03 in Adult Participants With Active Cutaneous Lupus Erythematosus With or Without Systemic Lupus Erythematosus

Systemic Lupus ErythematosusSLESLE (Systemic Lupus)+2 more
Ventus Therapeutics U.S., Inc.24 enrolled27 locationsNCT07260877
Recruiting
Phase 1

A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Systemic Lupus Erythematosus

SLESLE (Systemic Lupus)
Cullinan Therapeutics Inc.24 enrolled15 locationsNCT06613360
Recruiting
Early Phase 1

Clinical Study on Targeted CD19 or CD19-BCMA CAR-T Therapy for Autoimmune Diseases

SLE (Systemic Lupus)Systemic Sclerosis
Nanjing Bioheng Biotech Co., Ltd.20 enrolled1 locationNCT06548607
Recruiting
Phase 1

A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease

SLE (Systemic Lupus)Diffuse Cutaneous Systemic SclerosisSystemic Sclerosis+4 more
CRISPR Therapeutics80 enrolled8 locationsNCT06925542
Recruiting
Phase 1

Phase 1a/b Tolerability of NTR-1011 in Healthy Adults and Adult Patients With SLE and RA

SLE (Systemic Lupus)RA - Rheumatoid Arthritis
Neutrolis48 enrolled1 locationNCT07237659
Recruiting
Phase 1

Safety and Efficacy of CD19 Targeted CAR-T Therapy for Refractory Autoimmune Disease

DermatomyositisSystemic SclerodermaAnti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis+2 more
Chongqing Precision Biotech Co., Ltd24 enrolled1 locationNCT06056921
Recruiting

National Systemic Lupus Erythematosus Prospective Cohort, Saudi Arabia

SLE (Systemic Lupus)
King Saud University1,000 enrolled1 locationNCT04604990