Phase 1 Smoking Clinical Trials

10 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 110 of 10 trials

Recruiting
Phase 1

Development of a MHBC Intervention for Weight Loss and Smoking Cessation for Pre-Bariatric Surgery Patients

ObesitySmoking CessationBariatric Surgery Patients
Yale University20 enrolled1 locationNCT07224087
Recruiting
Phase 1

Nordic Spirit Pouch Nicotine Pharmacokinetics Abuse Liability

Smoking Behaviors
JT International SA55 enrolled2 locationsNCT07476144
Recruiting
Phase 1

Effect of Cannabis on Cigarette Use Behavior

Cannabis UseTobacco UseCigarette Smoking
Johns Hopkins University100 enrolled1 locationNCT06609083
Recruiting
Phase 1

Oral Cannabidiol for Tobacco Cessation

Tobacco Use DisorderTobacco DependenceTobacco Use Cessation+2 more
Johns Hopkins University50 enrolled1 locationNCT05445804
Recruiting
Phase 1

Imaging Sex Differences in Smoking-Induced Pulmonary Inflammation

Healthy VolunteerSmoking, CigaretteSmoking E-cigarette
University of Pennsylvania100 enrolled1 locationNCT03721822
Recruiting
Phase 1

Effects of Cannabidiol on Stress and Nicotine Withdrawal

StressNicotine DependenceTobacco Smoking+1 more
Johns Hopkins University90 enrolled1 locationNCT07001930
Recruiting
Phase 1Phase 2

Overcoming Nicotine Dependence to Enable Quitting

Smoking CessationSmoking BehaviorsNicotine Dependence+2 more
Rush University Medical Center780 enrolled1 locationNCT05513872
Recruiting
Phase 1

Concurrent vs. Sequential Cessation of Dual Cigarette and E-cigarette Use

Cigarette Smoking
Yale University40 enrolled1 locationNCT06027840
Completed
Phase 1

Tobacco Harm Reduction with Vaporised Nicotine (THRiVe): Feasibility Study

Smoking
The University of Queensland30 enrolled1 locationACTRN12616001641482
Completed
Phase 1

Cytisine as a smoking cessation aid: measuring blood levels, craving, withdrawal and mood over a course of treatment

Smoking
University of Auckland12 enrolled1 locationACTRN12613000002785