Phase 1 Solid Cancers Clinical Trials

9 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 19 of 9 trials

Recruiting
Phase 1Phase 2

A Clinical Trial to Test if the Investigational Drug BNT329 is Safe and Potentially Beneficial for People With Advanced Solid Tumors Known to Express the Tumor Marker CA19-9

Advanced Solid Cancers
BioNTech SE245 enrolled8 locationsNCT07186842
Recruiting
Phase 1

An Antibody-armored Dendritic Cell in Patients With Solid Tumors

Adjuvant TherapySolid Cancers
Shanghai Cell Therapy Group Co.,Ltd8 enrolled1 locationNCT07479667
Recruiting
Phase 1

Autologous T-cells Genetically Engineered to Express Receptors Reactive Against KRAS Mutations in Conjunction With a Vaccine Directed Against These Antigens in Participants With Metastatic Cancer

Breast CancerColorectal, CancerOvarian Cancer+4 more
National Cancer Institute (NCI)210 enrolled1 locationNCT06253520
Recruiting
Phase 1

ADCX-020 for the Treatment of Patients With Locally Advanced or Metastatic Cancers

Metastatic Solid TumorsAdvanced Solid CancersAdvanced Malignancy
Adcytherix SAS290 enrolled4 locationsNCT07238075
Recruiting
Phase 1Phase 2

An Phase Ib/II Clinical Trial of TCC1727 Combination Therapy in Advanced Solid Tumors

Endometrial CancerGastric (Stomach) CancerNSCLC (Advanced Non-small Cell Lung Cancer)+2 more
Beijing Tide Pharmaceutical Co., Ltd266 enrolled3 locationsNCT07371663
Recruiting
Phase 1

Study of SC-102 in Patients With Advanced Solid Tumors

Advanced Solid Cancers
Tianjin ConjuStar Biologics Co., Ltd.120 enrolled1 locationNCT06710158
Recruiting
Phase 1

A Phase Ia/ Ib Study of HS387 in Subjects With Advanced Solid Tumors

Advanced Solid Cancers
Zhejiang Hisun Pharmaceutical Co. Ltd.110 enrolled1 locationNCT07092748
Recruiting
Phase 1

A Phase I Study of LXP1788 Injection with Advanced Solid Tumors.

Pancreas CancerSolid Tumor CancerHCC - Hepatocellular Carcinoma+6 more
LaunXP Biomedical Co., Ltd.24 enrolled2 locationsNCT06883539
Completed
Phase 1

A phase 1 clinical trial of BIL06v/Alhydrogel to evaluate the safety, tolerability, immunogenicity and anti-tumour activity and to determine the most effective dose of BIL06v/Alhydrogel to treat patients with advanced forms of solid cancers

Advanced Solid Cancers
Biosceptre (Aust) Pty Limited30 enrolled2 locationsACTRN12618000838213