Early Phase 1 Solid Tumor Clinical Trials

45 recruitingEarly Phase 1

What is a Early Phase 1 trial?

Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.

Showing 120 of 45 trials

Recruiting
Early Phase 1

NK521 in the Treatment of Malignant Ascites Associated With Advanced Solid Tumors

Advanced Solid Tumors
Base Therapeutics (Shanghai) Co., Ltd.18 enrolled1 locationNCT07561437
Recruiting
Early Phase 1

Exploring the Clinical Value of RT01-89Zr PET Imaging in Solid Tumors

Solid Tumors
Nanolattix Biotechnology Co., Ltd.10 enrolled1 locationNCT07505069
Recruiting
Early Phase 1

Clinical Study on the Efficacy and Safety of CAR-DC in the Treatment of Advanced Solid Tumors

Advanced Solid Tumors
Peking University Shenzhen Hospital10 enrolled1 locationNCT07504445
Recruiting
Early Phase 1

Functionally Enhanced ALPP-Targeted Engineered T Cells in Advanced Solid Tumors

Solid Tumor
TCRCure Biopharma Ltd.24 enrolled1 locationNCT07487597
Recruiting
Early Phase 1

A Phase I Study to Evaluate the Safety, Tolerability, and PK of HLX37 in Advanced/Metastatic Solid Tumors

NSCLCAdvanced/Metastatic Solid Tumors
Shanghai Henlius Biotech254 enrolled2 locationsNCT07274813
Recruiting
Early Phase 1

Indocyanine Green (ICG) Guided Sentinel Lymph Node Mapping for Pediatric Visceral Solid Tumors

Solid Tumor
St. Jude Children's Research Hospital25 enrolled3 locationsNCT05645523
Recruiting
Early Phase 1

A Single-Arm, Open-Label Clinical Study GK01 Cell Injection in Subjects With Advanced Solid Tumors.

Advanced Solid Tumors
Beijing Geekgene Technology Co., LTD10 enrolled1 locationNCT07414316
Recruiting
Early Phase 1

HEAT Trial (HER2 Antibody Therapy With Lutetium-177)

Advanced Solid TumorsHER2 Gene Mutation
Radiopharm Theranostics, Ltd30 enrolled5 locationsNCT06824155
Recruiting
Early Phase 1

This is a Multi-Center Study of IBI3026 in Participants With Locally Advanced, Unresectable or Metastatic Solid Tumors

Solid Tumor
Innovent Biologics Technology Limited (Shanghai R&D Center)300 enrolled1 locationNCT07327632
Recruiting
Early Phase 1

A Clinical Study of GK02 in Malignant Ascites

Malignant Ascites Caused by Advanced Solid Tumors
Beijing Geekgene Technology Co., LTD9 enrolled1 locationNCT07378436
Recruiting
Early Phase 1

Safety and Efficacy of Metabolically Armed Tumor-Infiltrating Lymphocytes (Meta10-TIL) for the Treatment of Advanced Solid Tumors

Advanced Solid Tumors
Cancer Institute and Hospital, Chinese Academy of Medical Sciences36 enrolled1 locationNCT07349160
Recruiting
Early Phase 1

PET-imaging of Two Vartumabs in Patients With Solid Tumors

Breast CancerBladder CarcinomaEsophageal Carcinoma+11 more
Var2 Pharmaceuticals32 enrolled1 locationNCT06645808
Recruiting
Early Phase 1

A Clinical Study on Evaluating Intravenous Administration of IDOV-SAFE

Advanced Malignant Solid Tumor of Digestive System
Peking University89 enrolled1 locationNCT06380309
Recruiting
Early Phase 1

A Study of TIL in Advanced Solid Tumors (DFGD)

Advanced Solid TumorTreatment Side EffectsEffects of Immunotherapy+1 more
Shanghai Juncell Therapeutics30 enrolled1 locationNCT06488950
Recruiting
Early Phase 1

A Study of GC101 TIL in Advanced Solid Tumors (TR)

Advanced Solid Tumors
Shanghai Juncell Therapeutics20 enrolled1 locationNCT04967833
Recruiting
Early Phase 1

Safety and Efficacy of Metabolically Armed Tumor-lnfiltrating Lymphocytes (Meta10-TIL) for the Treatment of Advanced Solid Tumors

Advanced Solid Tumors
Anhui Provincial Hospital36 enrolled1 locationNCT07106814
Recruiting
Early Phase 1

HF50 in HER-2 Positive and Low-expression Advanced Solid Tumors

Advanced Solid Tumors
HighField Biopharmaceuticals Corporation10 enrolled1 locationNCT06822998
Recruiting
Early Phase 1

Study of KRAS Neoantigen mRNA Vaccine (ABO2102) in Patients With KRAS -Mutated Solid Tumors

Pancreatic NeoplasmsOther Solid Tumors
Ruijin Hospital56 enrolled1 locationNCT06577532
Recruiting
Early Phase 1

An Exploratory Study of Individualized Neo-antigen mRNA Cancer Vaccine InnoPCV in Advanced Solid Tumor Treatment

Advanced Solid Tumor
The Affiliated Hospital Of Guizhou Medical University40 enrolled1 locationNCT06497010
Recruiting
Early Phase 1

AMT-676 in Patients With Advanced Solid Tumors

Advanced Solid Tumors
Multitude Therapeutics Inc.24 enrolled13 locationsNCT06400485