Phase 3 Solid Tumor Clinical Trials

14 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 114 of 14 trials

Recruiting
Phase 3

Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

Solid TumorsHematologic Malignancies
Merck Sharp & Dohme LLC3,500 enrolled779 locationsNCT03486873
Recruiting
Phase 3

A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma

Solid Tumors
Incyte Corporation588 enrolled212 locationsNCT07522073
Recruiting
Phase 2Phase 3

PRO-BOOST-N: Prostate-First Versus Combined Prostate and Nodal Dose Escalation in PSMA PET-Staged Node-Positive Prostate Cancer

Prostate CancerBrachytherapyStereotactic Body Radiation Therapy (SBRT)+2 more
Affidea Nu-med Center of Oncological DIagnostics and Therapy1,600 enrolled1 locationNCT07426094
Recruiting
Phase 2Phase 3

PRO-BOOST-LC: Whole-Gland Boost Strategies Versus SBRT Monotherapy in PSMA-Staged Localized and Locally Advanced Prostate Cancer

Prostate Cancer (Adenocarcinoma)Stereotactic Body Radiation Therapy (SBRT)Localized Prostate Cancer+2 more
Affidea Nu-med Center of Oncological DIagnostics and Therapy1,200 enrolled1 locationNCT07426055
Recruiting
Phase 2Phase 3

Pan-tumor Neoadjuvant Basket Study of Immune Check-point Inhibition and Novel Immuno-oncology Combinations

Resectable MMR-deficient Solid TumorsResectable MMR-proficient Solid Tumors
The Netherlands Cancer Institute133 enrolled1 locationNCT06279130
Recruiting
Phase 3

Lattice Radiation Therapy Versus Conventional Radiation Therapy for the Palliation of Large Tumors

Histopathologically or Cytologically Confirmed Solid Tumor Who Require Palliation Radiation Therapy to a Lesion ≥5cm
University Health Network, Toronto148 enrolled1 locationNCT07444775
Recruiting
Phase 2Phase 3

HMPL-453 Tartrate in Advanced Intrahepatic Cholangiocarcinoma

Solid Tumor, AdultAdvanced Intrahepatic Cholangiocarcinoma
Hutchmed235 enrolled1 locationNCT04353375
Recruiting
Phase 2Phase 3

Trop2-targeted immunoPET Imaging of Solid Tumors

Liver CancerOvarian CancerCervical Cancer+11 more
RenJi Hospital400 enrolled1 locationNCT06851663
Recruiting
Phase 3

Trial to Evaluate irAEs With Different Standard of Care Dosing Strategies of Standard of Care Immunotherapies

Solid Tumor Malignancies
University of Kansas Medical Center192 enrolled1 locationNCT07174453
Recruiting
Phase 3

An Extension Study for Patients Previously Enrolled in Studies With Pelabresib

Solid TumorHematologic MalignancyAdvanced Malignancies
Novartis Pharmaceuticals50 enrolled15 locationsNCT06401356
Recruiting
Phase 3

Phase III Clinical Study of VC004 in Patients With Localized Advanced/ Metastatic Solid Tumors

Locally Advanced Solid Tumor
Jiangsu vcare pharmaceutical technology co., LTD54 enrolled1 locationNCT06658353
Recruiting
Phase 2Phase 3

To Evaluate IAH0968 in Combination With CAPEOX in HER2-positive Gastric Cancer

Stomach NeoplasmsSolid Tumor
SUNHO(China)BioPharmaceutical CO., Ltd.90 enrolled2 locationsNCT06504732
Recruiting
Phase 2Phase 3

Interventional Software for Multi-immunotherapy of Solid Tumors

Liver CancerLung CancerSolid Tumor, Adult
Second Affiliated Hospital of Guangzhou Medical University60 enrolled1 locationNCT06478108
Recruiting
Phase 3

Ondansetron (ODF) Versus Ondansetron Intravenously for the Prevention of Chemotherapy-induced Nausea and Vomiting Compare in Children

Pediatric Solid Tumor, Unspecified, Protocol Specific
Yizhuo Zhang376 enrolled1 locationNCT06208917