Phase 2 Solid Tumours Clinical Trials
17 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–17 of 17 trials
Recruiting
Phase 2
Beamion PANTUMOR-1: A Study to Test Whether Zongertinib Helps People With Advanced Cancers With HER2 Alterations
Solid Tumours
Boehringer Ingelheim430 enrolled88 locationsNCT06581432
Recruiting
Phase 1Phase 2
Study of AZD4956 as Monotherapy and in Combination With Anti-Cancer Agents in Participants With Advanced/Metastatic Homologous Recombination Deficient Solid Tumours
Solid Tumours
AstraZeneca180 enrolled18 locationsNCT07446855
Recruiting
Phase 1Phase 2
A Phase 1/2a, First-in-human, Study of BMS-986517 in Participants With Advanced Solid Tumors
Solid Tumours
Bristol-Myers Squibb315 enrolled19 locationsNCT07160725
Recruiting
Phase 1Phase 2
Phase 1/2 Study of PYX-201 in Combination With Pembrolizumab in Advanced Solid Tumors
Advanced Solid Tumours
Pyxis Oncology, Inc220 enrolled15 locationsNCT06795412
Recruiting
Phase 1Phase 2
A Phase 1/2, First-in-Human Study On ODM-212 In Subjects With Selected Advanced Solid Tumours
Solid Tumours
Orion Corporation, Orion Pharma315 enrolled1 locationNCT06725758
Recruiting
Phase 2Phase 3
DETERMINE Trial Treatment Arm 02: Atezolizumab in Adult, Paediatric and Teenage/Young Adult Patients With Cancers With High Tumour Mutational Burden (TMB) or Microsatellite Instability-high (MSI-high) or Proven Constitutional Mismatch Repair Deficiency (CMMRD) Disposition
MalignancyMelanomaCancer+7 more
Cancer Research UK30 enrolled27 locationsNCT05770102
Recruiting
Phase 1Phase 2
A Study of LM-168 as a Single Agent or in Combination With Toripalimab in Subjects With Advanced Solid Tumours
Advanced Solid Tumours
LaNova Medicines Limited87 enrolled6 locationsNCT06868199
Recruiting
Phase 1Phase 2
A Phase I/II Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Initial Efficacy of JS212 in Subjects With Advanced Malignant Solid Tumour
Advanced Malignant Solid Tumours
Shanghai Junshi Bioscience Co., Ltd.374 enrolled1 locationNCT06888830
Recruiting
Phase 1Phase 2
Aims to Explore the Safety, Tolerability, and Preliminary Efficacy of SCTB41 in Adult Patients with Advanced Malignant Solid Tumours.
Advanced Malignant Solid Tumours
Sinocelltech Ltd.441 enrolled1 locationNCT06600022
Recruiting
Phase 1Phase 2
A Phase I/II Trial of UCB4594 in Participants With Advanced Cancer
Squamous Cell Carcinoma of Head and NeckAdvanced Solid Tumours
Cancer Research UK167 enrolled2 locationsNCT06380816
Recruiting
Phase 1Phase 2
A Study of RC88 Combined With Sintilimab for Advanced Solid Tumours
Advanced Solid Tumours
RemeGen Co., Ltd.82 enrolled1 locationNCT05804526
Recruiting
Phase 2
Safety and Efficacy of NOX66 in combination with Nivolumab for patients with solid tumours – a pilot study (IONIC-1).
Patients with solid tumours
Cancer Care Foundation Limited30 enrolled4 locationsACTRN12621001537842
Terminated
Phase 2
A Phase 2 clinical trial to assess the safety and efficacy of ACT001 in combination with whole brain radiation therapy (WBRT) for participants with brain metastases from solid tumours.
Solid TumoursMetastatic Brain Cancer
Accendatech Au Pty Ltd20 enrolled1 locationACTRN12621000093886
Recruiting
Phase 2
A clinical trial to assess the safety, tolerability and efficacy of MG010 in combination with sorafenib-(Nexavar), in people with solid tumours who have failed existing treatments.
Metastatic solid tumours having failed existing treatments.
Metagone Biotech Australia Pty Ltd50 enrolled4 locationsACTRN12620000849998
Terminated
Phase 2
A study of EnGeneIC Dream Vectors (EDV's) packaged with the chemotherapy, E-EDV-D682 given simultaneously as non-targeted EDVs carrying an immune enhancer called EDV-GC, in participants with advanced pancreatic and other cancers whose disease has progressed after one or two treatment regimes, or where other standard therapies are not appropriate.
Advanced Cancer (Solid Tumours)Pancreatic Cancer
EnGeneIC Pty Limited80 enrolled2 locationsACTRN12619000385145
Completed
Phase 2
IPINIVO - A Pharmacodynamics study of Nivolumab in Combination with Ipilimumab in Patients with Advanced or Metastatic Solid Tumours'
Advanced or Metastatic Solid Tumours
Clinical Network Services21 enrolled1 locationACTRN12617001059358
Terminated
Phase 2
Dose finding study for CRLX301 in solid tumors
Taxane-naive castration resistant prostate cancer (CRPC)Solid Tumours
BlueLink Pharmaceuticals a subsidiary of NewLink Genetics118 enrolled4 locationsACTRN12614001292662