Phase 1 Solid Tumours Clinical Trials
35 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 35 trials
Recruiting
Phase 1Phase 2
Study of AZD4956 as Monotherapy and in Combination With Anti-Cancer Agents in Participants With Advanced/Metastatic Homologous Recombination Deficient Solid Tumours
Solid Tumours
AstraZeneca180 enrolled18 locationsNCT07446855
Recruiting
Phase 1
A Phase I Dose Escalation and Dose Expansion Study to Investigate the Pharmacokinetics and Safety of Subcutaneous Durvalumab
Solid Tumours
AstraZeneca40 enrolled19 locationsNCT07391670
Recruiting
Phase 1
A Study in People With Advanced Cancer (Solid Tumours) to Test Different Doses of BI 3810944 and to Find Out Whether it Helps
MelanomaSolid Tumours
Boehringer Ingelheim69 enrolled6 locationsNCT07224425
Recruiting
Phase 1Phase 2
A Phase 1/2a, First-in-human, Study of BMS-986517 in Participants With Advanced Solid Tumors
Solid Tumours
Bristol-Myers Squibb315 enrolled19 locationsNCT07160725
Recruiting
Phase 1
A Phase I Open-Label, Single-Arm, Dose-Escalation Clinical and Pharmacology Study of CCI-001 as Monotherapy and in Combination With Standard Chemotherapy in Patients With Recurrent and/or Metastatic Solid Tumours
Cancer: Recurrent and/or Metastatic Solid Tumours
PharmaMatrix Holdings Ltd70 enrolled1 locationNCT04823897
Recruiting
Phase 1Phase 2
Phase 1/2 Study of PYX-201 in Combination With Pembrolizumab in Advanced Solid Tumors
Advanced Solid Tumours
Pyxis Oncology, Inc220 enrolled15 locationsNCT06795412
Recruiting
Phase 1
First in Human Study of AZD9592 in Solid Tumors
Advanced Solid Tumours
AstraZeneca403 enrolled50 locationsNCT05647122
Recruiting
Phase 1
A Study of EBC-129 in Advanced Solid Tumours
Advanced Solid Tumours
EDDC (Experimental Drug Development Centre), A*STAR Research Entities98 enrolled5 locationsNCT05701527
Recruiting
Phase 1
First in Human Study of SIM0610 in Solid Tumors
Advanced Solid Tumours
Jiangsu Simcere Pharmaceutical Co., Ltd.260 enrolled7 locationsNCT07348211
Recruiting
Phase 1Phase 2
A Phase 1/2, First-in-Human Study On ODM-212 In Subjects With Selected Advanced Solid Tumours
Solid Tumours
Orion Corporation, Orion Pharma315 enrolled1 locationNCT06725758
Recruiting
Phase 1
A Study of AP601 in Patients With Locally Unresectable Advanced or Metastatic Solid Tumors
Solid Tumours
AP Biosciences Inc.36 enrolled3 locationsNCT07165067
Recruiting
Phase 1
A Safety and Pharmacokinetics Study of RC220 Combined With Doxorubicin in Adult Participants With Solid Tumours.
Advanced Solid TumoursSolid Tumours
Race Oncology Ltd53 enrolled5 locationsNCT06815575
Recruiting
Phase 1Phase 2
A Study of LM-168 as a Single Agent or in Combination With Toripalimab in Subjects With Advanced Solid Tumours
Advanced Solid Tumours
LaNova Medicines Limited87 enrolled6 locationsNCT06868199
Recruiting
Phase 1
A Phase 1, First-in-human Study of OKN4395 and Pembrolizumab in Patients With Solid Tumors
SarcomaHNSCCSolid Tumours
Epkin166 enrolled10 locationsNCT06789172
Recruiting
Phase 1Phase 2
A Phase I/II Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Initial Efficacy of JS212 in Subjects With Advanced Malignant Solid Tumour
Advanced Malignant Solid Tumours
Shanghai Junshi Bioscience Co., Ltd.374 enrolled1 locationNCT06888830
Recruiting
Phase 1
A Trial to Evaluate Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of BA1301 in Advanced Solid Tumors.
Advanced Solid Tumours
Shandong Boan Biotechnology Co., Ltd70 enrolled1 locationNCT06927349
Recruiting
Phase 1
Human Epidermal Growth Factor Receptor 2 (HER2) Antibody Therapy with Lutetium-177 in Patients with Advanced Solid Tumours.
Advanced Solid Tumours
Radiopharm Theranostics Ltd24 enrolled4 locationsACTRN12625000191493
Recruiting
Phase 1Phase 2
Aims to Explore the Safety, Tolerability, and Preliminary Efficacy of SCTB41 in Adult Patients with Advanced Malignant Solid Tumours.
Advanced Malignant Solid Tumours
Sinocelltech Ltd.441 enrolled1 locationNCT06600022
Recruiting
Phase 1Phase 2
A Phase I/II Trial of UCB4594 in Participants With Advanced Cancer
Squamous Cell Carcinoma of Head and NeckAdvanced Solid Tumours
Cancer Research UK167 enrolled2 locationsNCT06380816
Recruiting
Phase 1Phase 2
A Study of RC88 Combined With Sintilimab for Advanced Solid Tumours
Advanced Solid Tumours
RemeGen Co., Ltd.82 enrolled1 locationNCT05804526