Phase 2 SpA Clinical Trials
28 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 28 trials
Recruiting
Phase 1Phase 2
EAST-1 (ERAP-inhibition in Axial Spondyloarthritis Trial - 1)
Axial Spondyloarthritis (AxSpA)
Grey Wolf Therapeutics141 enrolled15 locationsNCT07047703
Recruiting
Phase 2
A Study in Participants With Anti-NMDAR Encephalitis and Anti-NMDAR Autoantibody-Associated Psychiatric Disease
Autoimmune EncephalitisAnti-N-methyl-D-aspartate Receptor (NMDAR) Encephalitis (ANRE)Anti-N-methyl-D-aspartate Receptor (NMDAR) Antibody-associated Psychiatric Disease
Arialys Australia Pty Ltd30 enrolled1 locationNCT07093333
Recruiting
Phase 2
A Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368 in Participants With Multiple Sclerosis Spasticity
Multiple Sclerosis Spasticity
Celgene200 enrolled54 locationsNCT06782490
Recruiting
Phase 2
A Study of SPY072 in Rheumatic Disease
Rheumatoid ArthritisPsoriatic ArthritisRheumatic Diseases+5 more
Spyre Therapeutics, Inc.285 enrolled64 locationsNCT07148414
Recruiting
Phase 1Phase 2
A Study to Assess the Safety and Efficacy of IPN10200 in Adult Participants With Upper Limb Spasticity.
Spasticity
Ipsen240 enrolled81 locationsNCT04752774
Recruiting
Phase 2Phase 3
Comparison of the Pharmacokinetics (PK) and Pharmacodynamics (PD) Biosimilarity of Proposed Biosimilar/Interchangeable Rapid-Acting Insulin Aspart (I004) and NovoLog® After Single-Dose Subcutaneous Administration to Healthy Volunteers
PharmacokineticsPharmacodynamicsInsulin Aspart
Amphastar Pharmaceuticals, Inc.60 enrolled1 locationNCT07560150
Recruiting
Phase 2Phase 3
The Investigators Will Evaluate the Diagnostic Performance of [18F]-AlF-FAPI-74 PET/CT in Inflammatory Disorders and Compare it With the Current Gold Standard for Inflammation, FDG PET/CT, in Three Patient Cohort: Patients Presenting With Fever of Unknown Origin, IgG4-RD and AxSpA.
Axial Spondylarthritis (axSpA)IgG4-related DiseaseInflammation of Unknown Origin+1 more
Universitaire Ziekenhuizen KU Leuven140 enrolled1 locationNCT07535554
Recruiting
Phase 2
Treatment of Refractory Infantile Spasms With Fenfluramine
Infantile Spasm
Children's Hospital of Orange County10 enrolled2 locationsNCT04289467
Recruiting
Phase 2
Topical Ketotifen 0.25% for Secondary Vestibulodynia
VulvodyniaProvoked VestibulodyniaSecondary Provoked Vestibulodynia+4 more
Center for Vulvovaginal Disorders54 enrolled3 locationsNCT07257029
Recruiting
Phase 2
Family Acceptance Project Online (Pilot RCT)
DepressionAnxietyDrug Use+6 more
University of Michigan180 enrolled1 locationNCT06839859
Not Yet Recruiting
Phase 2
A Multicenter, Randomized, Fixed Sequence, Cross-over Study to Assess the Safety, Tolerability, and Pharmacokinetics of MRX-4TZT TDS (Tizanidine Transdermal Delivery System) versus Oral Tizanidine in Multiple Sclerosis Patients with Established Spasticity
Multiple SclerosisSpasticity
MEDRx Australia Pty Ltd80 enrolled1 locationACTRN12626000112369
Recruiting
Phase 2Phase 3
A Clinical Study on Recombinant Botulinum Toxin Type A (YY001) for Injection in The Treatment of Upper Limb Spasticity in Adults
Upper Limb Spasticity
Chongqing Claruvis Pharmaceutical Co., Ltd.254 enrolled24 locationsNCT06783114
Recruiting
Phase 2
Nephron-sparing Treatment of Tislelizumab + Nab-Paclitaxel for Renal Pelvic Cancer
TislelizumabPD-1 InhibitorKidney-sparing+2 more
Tianjin Medical University Second Hospital35 enrolled1 locationNCT07233252
Recruiting
Phase 2
Neoadjuvant Tislelizumab + Nab-Paclitaxel Followed by Distal Ureterectomy for Ureteral Cancer
Neoadjuvant TherapyTislelizumabPD-1 Inhibitor+3 more
Tianjin Medical University Second Hospital35 enrolled1 locationNCT07125547
Recruiting
Phase 2Phase 3
Therapeutic Photobiomodulation and Tretament of Spasticity
Muscle SpasticityCerebral PalsyPhotobiomodulation+1 more
University of Nove de Julho28 enrolled2 locationsNCT06536751
Recruiting
Phase 2
A Study of Magnesium and Bladder Spasms Following Ambulatory Urologic Procedures
Bladder Spasms
Mayo Clinic120 enrolled1 locationNCT05806996
Recruiting
Phase 2
A Study to Prevent Infantile Spasms Relapse
West SyndromeInfantile SpasmsInfantile Epileptic Spasms Syndrome
University of California, Los Angeles40 enrolled1 locationNCT06819670
Recruiting
Phase 2Phase 3
Efficacy of Targeted Medical Therapy in Angina and Nonobstructive Coronary Arteries
Angina PectorisMicrovascular AnginaVasospastic Angina+1 more
Stanford University150 enrolled1 locationNCT06424834
Recruiting
Phase 2
Efficacy and Safety of Taitacept in Treatment of Refractory or Recurrent Anti-NMDAR/anti-LGI1 Encephalitis
Anti-N-Methyl-D-Aspartate Receptor Encephalitis
Beijing Tongren Hospital10 enrolled1 locationNCT06510283
Recruiting
Phase 1Phase 2
Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt)
Spasticity, MuscleSpastic ParaplegiaMicrocephaly+3 more
Elpida Therapeutics SPC4 enrolled1 locationNCT05518188