SpA Clinical Trials

1 recruiting

Frequently Asked Questions

Common questions about SpA clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 251 trials

Recruiting
Phase 3

A Study on Recombinant Botulinum Toxin Type A (YY001) for Injection in Multiple Treatments of Adult Upper Limb Spasticity

Upper Limb Spasticity
Chongqing Claruvis Pharmaceutical Co., Ltd.300 enrolled16 locationsNCT07478822
Recruiting

Classification of Upper and Lower Limb Spasticity Patterns and Their Impact on Quality of Life in Patients With Multiple Sclerosis

Multiple SclerosisSpasticitySpasticity With Multiple Sclerosis
Marmara University75 enrolled1 locationNCT07466823
Recruiting
Not Applicable

Effect of Task Specific Electrical Stimulation on Upper Limb Gross Motor Skills in Children With Spastic Quadriplegia

Spastic Cerebral PalsyCerebral Palsy (CP)Upper Limb Function+2 more
Kafrelsheikh University30 enrolled1 locationNCT06925425
Recruiting
Not Applicable

Effectiveness of Radiofrequency Combined With Ultrasound for the Treatment of Postpartum Dyspareunia

Postpartum Dyspareunia
Institut Investigacio Sanitaria Pere Virgili34 enrolled1 locationNCT07504991
Recruiting
Phase 1

Shockwave for Elbow and Wrist Spasticity in People With Spinal Cord Injury

Spinal Cord InjurySpasticityShockwave Therapy
Kessler Foundation12 enrolled1 locationNCT07501429
Recruiting

Neurosurgical Outcome Network

Trigeminal NeuralgiaHydrocephalusSubarachnoid Hemorrhage+14 more
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta4,500 enrolled27 locationsNCT06724029
Recruiting
Not Applicable

Worldwide Yearly Screening for Hypospadias

Hypospadias
University of Wisconsin, Madison20 enrolled1 locationNCT06966375
Recruiting
Not Applicable

Changes in the Impact of Genitourinary Syndrome of Menopause With a Novel Nonhormonal Vulvovaginal Gel Assessed by PROMs.

Sexual FunctionQuality of LifeGenitourinary Syndrome of Menopause+5 more
Mucosa Innovations, S.L.80 enrolled1 locationNCT06962345
Recruiting
Not Applicable

Advancing Diagnosis and Treatment of Pediatric Asthma

AsthmaAsthma ChildhoodInhalation Spacers
Luxembourg Institute of Health208 enrolled1 locationNCT07500246
Recruiting

Peer-Support Breastfeeding Program for Mothers in Severe Socioeconomic Deprivation: Feasibility Study

Health DisparitiesBreastfeedingBreastfeeding Support+1 more
Hospices Civils de Lyon50 enrolled1 locationNCT07499466
Recruiting
Not Applicable

Biomarkers of Reaction To HIIT Exercise

Stroke RehabilitationStrokeWalking, Difficulty+1 more
VA Office of Research and Development55 enrolled1 locationNCT06059872
Recruiting
Phase 2

A Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368 in Participants With Multiple Sclerosis Spasticity

Multiple Sclerosis Spasticity
Celgene200 enrolled53 locationsNCT06782490
Recruiting

STOP-HSP.Net: a Registry for Hereditary Spastic Paraplegia as an Integration Tool for Future Therapeutic Strategies

Hereditary Spastic Paraplegia
IRCCS Fondazione Stella Maris500 enrolled1 locationNCT06572046
Recruiting
Not Applicable

Patients and Families Improving Safety in Hospitals by Actively Reporting Experiences

Health DisparitiesPatient SafetyQuality Improvement+3 more
Boston Children's Hospital656 enrolled1 locationNCT05407129
Recruiting
Not Applicable

Comparing Prism Adaptation Training With and Without TENS to Minimize Unilateral Spatial Neglect

StrokeUnilateral Spatial Neglect
Kettering Health Network20 enrolled2 locationsNCT07157865
Recruiting
Not Applicable

Comparison of Sacral ESP Block and Dorsal Penile Nerve Block in Pediatric Hypospadias Surgery

Postoperative PainHypospadias
Medipol University70 enrolled1 locationNCT07426731
Recruiting
Not Applicable

The Effectiveness of Different Pulse Duration of NMES in Patients With Pyramidal Tract-related Spasticity Measured by Neurophysiological Tools

Pyramidal Tract-related SpasticityUpper Motor Neuron Lesion
University of West Attica45 enrolled1 locationNCT07321158
Recruiting
Not Applicable

Impact of rTMS Combined With Neurorehabilitation on Lower Extremity Motor Function and Spasticity in Children With Spastic Diplegic Cerebral Palsy

Cerebral Palsy (CP)Transcranial Magnetic StimilationDiplegic Cerebral Palsy With Spasticity+1 more
Ankara City Hospital Bilkent20 enrolled1 locationNCT07488429
Recruiting
Not Applicable

Strategy Training for Optimizing Attention for Individuals With Spatial Neglect

StrokeNeglect, Hemispatial
University of Pittsburgh45 enrolled1 locationNCT07331896
Recruiting
Not Applicable

Upper Limb Nerve Cryoneurolysis is Non Inferior to the Usual Care and Has Therapeutic Add Value in Dealing With Shoulder Pain and Functional Problems Caused by Spasticity and Motor Impairment

Traumatic Brain InjuryStrokeMultiple Sclerosis+5 more
Centre National de Rééducation Fonctionnelle et de Réadaptation50 enrolled1 locationNCT06782464