SpA Clinical Trials

287 recruitingLast updated: May 21, 2026

There are 287 actively recruiting spa clinical trials across 57 countries. Studies span Not Applicable, Phase 2, Phase 3, Phase 1, Phase 4, Early Phase 1. Top locations include Boston, Massachusetts, United States, Shanghai, Shanghai Municipality, China, Houston, Texas, United States. Updated daily from ClinicalTrials.gov.


SpA Trials at a Glance

287 actively recruiting trials for spa are listed on ClinicalTrialsFinder across 6 cities in 57 countries. The largest study group is Not Applicable with 155 trials, with the heaviest enrollment activity in Boston, Shanghai, and Houston. Lead sponsors running spa studies include Universitaire Ziekenhuizen KU Leuven, Cairo University, and Boston Children's Hospital.

About SpA Clinical Trials

Looking for clinical trials for SpA? There are currently 1 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new SpA trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about SpA clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 287 trials

Recruiting
Not Applicable

Spatial-Motor Stroke-Rehab Study

spatial neglectStroke
Emory University65 enrolled3 locationsNCT06053320
Recruiting
Not Applicable

Sensory Walkway and Gait in Children With Diplegic Cerebral Palsy

Spastic Diplegic Cerebral Palsy
Cairo University44 enrolled1 locationNCT07595744
Recruiting
Not Applicable

Breaking Silence Through Story: A Narrative Medicine Intervention for Parents of Children With Urogenital Conditions

DSDHypospadias
Sarah Schlegel20 enrolled1 locationNCT06989593
Recruiting

A Study to Assess Disease Activity in Adult Participants With Axial Spondyloarthritis Who Receive Upadacitinib in a Real-world Setting

Axial Spondylarthritis (r-axSpA)
AbbVie352 enrolled72 locationsNCT05094128
Recruiting
Phase 1Phase 2

EAST-1 (ERAP-inhibition in Axial Spondyloarthritis Trial - 1)

Axial Spondyloarthritis (AxSpA)
Grey Wolf Therapeutics141 enrolled15 locationsNCT07047703
Recruiting
Not Applicable

the Objective of This Research is to Compare the Clinical Effectiveness of the Conventional Lingual Arch Space Maintainers With Three-dimensional Printed Space Maintainers.

Gingival HealthPain and AnxietySpace Maintenance
Suez Canal University44 enrolled1 locationNCT07591324
Recruiting

Evaluation of Brain MRI Changes in Cerebral Palsy Patients

Cerebral PalsySpastic DiplegiaSpastic Quadriplegia+1 more
Columbia University30 enrolled1 locationNCT07433647
Recruiting
Not Applicable

Strategy Training for Optimizing Attention for Individuals With Spatial Neglect

StrokeNeglect, Hemispatial
University of Pittsburgh45 enrolled1 locationNCT07331896
Recruiting

Coronary Microvascular Dysfunction Assessments in Myocardial Infarction With Non-Obstructive Coronary Arteries

Myocardial InfarctionCoronary Microvascular DysfunctionVasospasm, Coronary
Chonnam National University Hospital150 enrolled1 locationNCT05272618
Recruiting
Phase 2

A Study in Participants With Anti-NMDAR Encephalitis and Anti-NMDAR Autoantibody-Associated Psychiatric Disease

Autoimmune EncephalitisAnti-N-methyl-D-aspartate Receptor (NMDAR) Encephalitis (ANRE)Anti-N-methyl-D-aspartate Receptor (NMDAR) Antibody-associated Psychiatric Disease
Arialys Australia Pty Ltd30 enrolled1 locationNCT07093333
Recruiting

Clinical Safety Guidelines for Managing Distal Shoe Complications

Premature loss of primary molarsSpace MaintainerSoft Tissue Inflammation
University of Florida50 enrolled2 locationsNCT07410442
Recruiting

Evaluation of Patients With HAM/TSP

HTLV-I InfectionTropical Spastic Paraparesis
National Institute of Neurological Disorders and Stroke (NINDS)750 enrolled1 locationNCT00001778
Recruiting
Phase 2

A Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368 in Participants With Multiple Sclerosis Spasticity

Multiple Sclerosis Spasticity
Celgene200 enrolled54 locationsNCT06782490
Recruiting
Not Applicable

Spatial Scene Recognition Memory in Epilepsy Surgery

Medically refractory epilepsyMemory deficitsMemory Disorders+9 more
University of California, Davis620 enrolled2 locationsNCT07580183
Recruiting
Phase 2

A Study of SPY072 in Rheumatic Disease

Rheumatoid ArthritisPsoriatic ArthritisRheumatic Diseases+5 more
Spyre Therapeutics, Inc.285 enrolled64 locationsNCT07148414
Recruiting

Reducing Disparities in Knee Arthroscopy for Adolescents

AdolescentACL InjuryMeniscus Tear+2 more
Ann & Robert H Lurie Children's Hospital of Chicago80 enrolled1 locationNCT07580625
Recruiting
Not Applicable

Feasibility Nutritional Supplements for Muscle Growth in CP

Spastic Cerebral Palsy
Universitaire Ziekenhuizen KU Leuven5 enrolled1 locationNCT06044168
Recruiting

3D-Microscopic Muscle Architecture in Cerebral Palsy

Spastic Cerebral Palsy
Universitaire Ziekenhuizen KU Leuven130 enrolled1 locationNCT06584851
Recruiting
Phase 1Phase 2

A Study to Assess the Safety and Efficacy of IPN10200 in Adult Participants With Upper Limb Spasticity.

Spasticity
Ipsen240 enrolled81 locationsNCT04752774
Recruiting
Not Applicable

tSCS in Children and Young People With HCP

Cerebral Palsy Spastic Hemiplegic
University of Leeds18 enrolled1 locationNCT07247812