SpA Clinical Trials

314 recruitingLast updated: July 25, 2026

There are 314 actively recruiting spa clinical trials across 59 countries. Studies span Not Applicable, Phase 2, Phase 3, Phase 1, Phase 4, Early Phase 1. Top locations include Boston, Massachusetts, United States, New York, New York, United States, Beijing, Beijing Municipality, China. Updated daily from ClinicalTrials.gov.


SpA Trials at a Glance

314 actively recruiting trials for spa are listed on ClinicalTrialsFinder across 6 cities in 59 countries. The largest study group is Not Applicable with 171 trials, with the heaviest enrollment activity in Boston, New York, and Beijing. Lead sponsors running spa studies include Universitaire Ziekenhuizen KU Leuven, Cairo University, and Boston Children's Hospital.

Treatments under study

About SpA Clinical Trials

Looking for clinical trials for SpA? There are currently 1 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new SpA trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about SpA clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 314 trials

Recruiting

Online Study of People Who Have Genetic Changes and Features of Autism: Simons Searchlight

SYNGAP1-Related Intellectual DisabilityDLG4FOXP1+184 more
Simons Searchlight100,000 enrolled2 locationsNCT01238250
Recruiting

Multicenter Validation of the 2025 Classification Criteria for Axial Spondyloarthritis

Spondyloarthritis (SpA)Axial Spondyloarthritis (AxSpA)Chronic Back Pain
Chinese PLA General Hospital247 enrolled1 locationNCT07724847
Recruiting
Not Applicable

Dorsal Root Electrical Stimulation in Children With Cerebral Palsy

Cerebral PalsyCerebral Palsy (CP)Spasticity+1 more
Martin Piazza15 enrolled1 locationNCT07715006
Recruiting

Evaluation of Patients With HAM/TSP

HTLV-I InfectionTropical Spastic Paraparesis
National Institute of Neurological Disorders and Stroke (NINDS)750 enrolled1 locationNCT00001778
Recruiting
Not Applicable

Effects of Proprioceptive Neuromuscular Facilitation and Task-Oriented Training on Upper Extremity Function in Children With Spastic Diplegic Cerebral Palsy

Cerebral PalsySpastic Diplegia
Ibadat International University, Islamabad63 enrolled1 locationNCT07694804
Recruiting
Not Applicable

Better Lifestyle Counseling for African American Women During Pregnancy

ExercisePregnancy ComplicationsStress, Psychological+9 more
University of Illinois at Chicago150 enrolled2 locationsNCT05234125
Recruiting
Phase 1Phase 2

Melpida: Recombinant Adeno-associated Virus (Serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt)

Spasticity, MuscleSpastic ParaplegiaMicrocephaly+3 more
Elpida Therapeutics SPC4 enrolled1 locationNCT05518188
Recruiting

Staging Strategies and Their Association With Prognosis and Therapy in Lung Cancer With Cystic Airspaces

Lung Cancer Associated With Cystic Airspaces
Central South University500 enrolled1 locationNCT07066813
Recruiting

Multi-omics Study of Early-stage Lung Cancer With Distinct Phenotypes

Non-small Cell Lung CancerLung Cancer Associated With Cystic AirspacesMultiple Primary Lung Cancers
Central South University300 enrolled1 locationNCT06699979
Recruiting
Not Applicable

Sugammadex-Induced Clenching During Neuromuscular Blockade Reversal

Perioperative ComplicationsAnesthesia GeneralSugammadex+3 more
Wonkwang University Hospital240 enrolled1 locationNCT06962007
Recruiting
Phase 1

Ketogenic Diet for Prevention of Epileptic Spasms in Infantile Onset Genetic Epilepsies

Genetic epilepsyDevelopmental and Epileptic EncephalopathiesEpileptic Spasms+1 more
Heather Olson10 enrolled1 locationNCT06700811
Recruiting

Human Sinonasal Mucosa Heterogeneity Study

Human Sinonasal Mucosal Spatial Atlas
First Affiliated Hospital, Sun Yat-Sen University100 enrolled1 locationNCT07692243
Recruiting

Clinical Safety Guidelines for Managing Distal Shoe Complications

Premature loss of primary molarsSpace MaintainerSoft Tissue Inflammation
University of Florida50 enrolled2 locationsNCT07410442
Recruiting
Not Applicable

Effect of Lower Extremity Modified Constraint-induced Movement Therapy on Locomotion in Children With Hemiplegia

Spastic Hemiplegic Cerebral Palsy
Cairo University30 enrolled1 locationNCT07686809
Recruiting
Not Applicable

Comparing Mixed Reality and Physical Therapy to Improve Balance and Coordination in Adolescents With Spastic Diplegic Cerebral Palsy

Cerebral PalsySpastic Diplegic Cerebral Palsy
Ibadat International University, Islamabad40 enrolled1 locationNCT07685327
Recruiting
Not Applicable

(CIRRUS-2023-1) CLINICAL CLIN Assessment of PathFinder 1.0 on the CIRRUS 6000 and the CIRRUS 5000

Dry Age-Related Macular DegenerationEpiretinal MembraneMacular Abnormalities+7 more
Carl Zeiss Meditec-Dublin CoCe400 enrolled6 locationsNCT07680244
Recruiting
Not Applicable

Improving Parental Support in Hypospadias Care

Hypospadias
University of North Carolina, Chapel Hill324 enrolled2 locationsNCT06832280
Recruiting
Phase 2

A Study of Magnesium and Bladder Spasms Following Ambulatory Urologic Procedures

Bladder Spasms
Mayo Clinic120 enrolled1 locationNCT05806996
Recruiting
Phase 1Phase 2

EAST-1 (ERAP-inhibition in Axial Spondyloarthritis Trial - 1)

Axial Spondyloarthritis (AxSpA)
Grey Wolf Therapeutics141 enrolled16 locationsNCT07047703
Recruiting
Not Applicable

Endovascular Therapy for Cerebral Vasospasm After Aneurysmal Subarachnoid Hemorrhage

Subarachnoid Hemorrhage, AneurysmalCerebral Vasospasm After Subarachnoid Hemorrhage
Beijing Tiantan Hospital306 enrolled2 locationsNCT07643922