Phase 1 Spinal Cord Injury Clinical Trials
19 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–19 of 19 trials
Recruiting
Phase 1Phase 2
Double Dose 4-AP on Functional Recovery After Spinal Cord Injury
SCI - Spinal Cord Injury
Shirley Ryan AbilityLab27 enrolled1 locationNCT06853015
Recruiting
Phase 1
FES Cycling With BFR in the Spinal Cord Injury Population
Spinal Cord InjuryMetabolic Diseases, Type 2 Diabetes, Cardiovascular DiseaseCardio Vascular Disease
Dr. B. Catharine. Craven6 enrolled1 locationNCT07588503
Recruiting
Phase 1Phase 2
Psilocybin to Treat Depression in Spinal Cord Injury
Depression - Major Depressive DisorderSpinal Cord InjuryVeteran
James J. Peters Veterans Affairs Medical Center30 enrolled1 locationNCT07251491
Recruiting
Phase 1
Shockwave for Elbow and Wrist Spasticity in People With Spinal Cord Injury
Spinal Cord InjurySpasticityShockwave Therapy
Kessler Foundation12 enrolled1 locationNCT07501429
Recruiting
Phase 1Phase 2
CE-STAND: Cervical Epidural STimulation After Neurologic Damage
Spinal Cord Injury
University of Minnesota36 enrolled1 locationNCT06410001
Recruiting
Phase 1
Safety and Feasibility of Intranasal Insulin in Patients With Spinal Cord Injury
Spinal Cord Injury
HealthPartners Institute12 enrolled1 locationNCT07384052
Recruiting
Phase 1Phase 2
NVG-291 in Spinal Cord Injury Subjects
chronic spinal cord injurySpinal Cord InjuriesSubacute Spinal Cord Injury
NervGen Pharma40 enrolled1 locationNCT05965700
Recruiting
Phase 1
A Study to Evaluate the Safety of a Delivery Device for Administering LCTOPC1 in Participants With Spinal Cord Injury
Spinal Cord InjurySpinal Cord Injury CervicalSpinal Cord Injury, Chronic+2 more
Lineage Cell Therapeutics, Inc.10 enrolled2 locationsNCT06841770
Recruiting
Phase 1
Spinal Cord Injury Neuroprotection With Glyburide
Acute Spinal Cord Injury
Francis Farhadi12 enrolled1 locationNCT05426681
Recruiting
Phase 1
Safety and Early Efficacy of iPSC-Derived Motor Neuron Progenitor Cells (XS228) in Subacute Spinal Cord Injury: A Phase I Trial
EfficacySafetySpinal Cord Injury+4 more
XellSmart Bio-Pharmaceutical (Suzhou) Co., Ltd.12 enrolled1 locationNCT06976229
Recruiting
Phase 1Phase 2
Improving 24-hour Blood Pressure Stability in Spinal Cord Injury With Low Oxygen Therapy
Spinal Cord Injury
Glen Foster10 enrolled2 locationsNCT06691165
Recruiting
Phase 1Phase 2
Phase 1b/2a Clinical Trial to Determine the Safety, Tolerability and Efficacy of TZ-161 in Spinal Cord Injury
Acute Spinal Cord Injury (SCI)
Technophage, SA28 enrolled2 locationsNCT06677229
Recruiting
Phase 1Phase 2
First-in-Human Clinical Trial of STUP-001, an In Vivo Direct Cell Conversion Gene Therapy for AIS-A/B Chronic Spinal Cord Injury
chronic spinal cord injurySpinal Cord Injury
Yonsei University9 enrolled1 locationNCT06922890
Recruiting
Phase 1Phase 2
Effects of CBD/CBD-A Oral Extract on Resting-state EEG and Neuropathic Pain Symptoms After SCI
Neuropathic PainSCI - Spinal Cord Injury
University of Miami20 enrolled1 locationNCT05630235
Recruiting
Phase 1
Exploring the Utility of [18F]3F4AP for Demyelination Imaging
Alzheimer's Disease(AD)MCIDemyelinating Disorders+3 more
Yale University105 enrolled1 locationNCT06999434
Recruiting
Phase 1Phase 2
Safety and Exploratory Efficacy of Transplantation Therapy Using PSA-NCAM(+) NPC in AIS-A Level of Sub-acute SCI
Spinal Cord Injury, AcuteSpinal Cord Injury at C4 Level With Complete LesionSpinal Cord Injury at C5-C7 Level With Complete Lesion
S.Biomedics Co., Ltd.5 enrolled2 locationsNCT04812431
Recruiting
Phase 1
NG004 in Spinal Cord Injury Patients
Central Nervous System DiseasesNervous System DiseasesTrauma, Nervous System+4 more
NovaGo Therapeutics AG21 enrolled6 locationsNCT06817577
Recruiting
Phase 1
Intravenous Immunoglobulin (IVIg) in Spinal Cord Injury
Spinal Cord Injury
University of Queensland40 enrolled1 locationACTRN12616001385437
Completed
Phase 1
A phase I single ascending dose (SAD) study to investigate the safety, tolerability and pharmacokinetics of oral Capromorelin in spinal cord injury (SCI) and able-bodied volunteers
Alleviating the effects of autonomic dysfunction following spinal cord injury.
University of Melbourne20 enrolled1 locationACTRN12614001122640