Spinal Clinical Trials in Philadelphia, Pennsylvania

18 recruitingPhiladelphia, Pennsylvania

Showing 118 of 18 trials

Recruiting
Phase 2

A Study to Assess the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of Intravenous Administration of ARGX-119 in Pediatric Participants Aged 5 to Less Than 18 Years With Spinal Muscular Atrophy

Spinal Muscular Atrophy (SMA)
argenx60 enrolled17 locationsNCT07287982
Recruiting

MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study

Lumbar Spinal Stenosis
Stryker Instruments8,000 enrolled2284 locationsNCT03072927
Recruiting
Phase 4

A Study Evaluating the Effectiveness and Safety of Risdiplam Administered in Pediatric Patients With Spinal Muscular Atrophy Who Experienced a Plateau or Decline in Function After Gene Therapy

Muscular Atrophy, Spinal
Hoffmann-La Roche28 enrolled19 locationsNCT05861999
Recruiting

Spinal Dural Arteriovenous Fistula International Data and Outcomes Registry

Spinal Dural Arteriovenous Fistula
Thomas Jefferson University1,000 enrolled1 locationNCT07574645
Recruiting
Phase 4

A Study Evaluating the Effectiveness and Safety of Risdiplam Administered as an Early Intervention in Pediatric Participants With Spinal Muscular Atrophy After Gene Therapy

Muscular Atrophy, Spinal
Hoffmann-La Roche28 enrolled16 locationsNCT05861986
Recruiting
Phase 2

A Study to Evaluate How Apitegromab Works in Subjects Who Are Less Than 2 Years Old and Have Spinal Muscular Atrophy

Spinal Muscular AtrophySMASpinal Muscular Atrophy Type 3+3 more
Scholar Rock, Inc.52 enrolled25 locationsNCT07047144
Recruiting
Not Applicable

Study of an Intrathecal Port and Catheter System for Subjects With Spinal Muscular Atrophy

Spinal Muscular AtrophyScoliosisSpine Deformity
Alcyone Therapeutics, Inc90 enrolled21 locationsNCT05866419
Recruiting
Phase 1

ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumors

Central Nervous System TumorGlioblastomaCNS Tumor+5 more
Sabine Mueller, MD, PhD208 enrolled6 locationsNCT04732065
Recruiting
Phase 1

A Study to Find Out How Nusinersen is Processed in the Body When Given Through the ThecaFlex DRx™ System in Adult and Pediatric Participants With Spinal Muscular Atrophy (PIERRE-PK)

Muscular Atrophy, Spinal
Biogen58 enrolled19 locationsNCT06555419
Recruiting

Nerve Transfer to Improve Function in High Level Tetraplegia

Cervical Spinal Cord Injurytetraplegia
Washington University School of Medicine30 enrolled10 locationsNCT06288763
Recruiting
Phase 1Phase 2

Dose Escalation Study of EG110A, Administered by Intradetrusor Injections to Adults With Neurogenic Detrusor Overactivity-related Incontinence Following Spinal Cord Injury Who Regularly Perform Clean Intermittent Catheterization

neurogenic detrusor overactivitySpinal Cord Injuries
EG 42716 enrolled4 locationsNCT06596291
Recruiting
Not Applicable

Non-Invasive Interventions for Respiratory Recovery in Chronic Spinal Cord Injury

Incomplete Spinal Cord InjurySpinal Cord Injury CervicalSpinal Cord Injury, Chronic+1 more
Thomas Jefferson University20 enrolled1 locationNCT07135583
Recruiting
Not Applicable

Systemic Hypothermia in Acute Cervical Spinal Cord Injury

Spinal Cord Injury, Acute
University of Miami120 enrolled7 locationsNCT02991690
Recruiting
Phase 2

Using Smartphones to Improve Physical Activity Levels of Individuals With Spinal Cord Injury

Spinal Cord Injuries
Temple University196 enrolled1 locationNCT05317832
Recruiting

The Myelin Disorders Biorepository Project

AdrenoleukodystrophyCockayne SyndromeRefsum Disease+63 more
Children's Hospital of Philadelphia12,000 enrolled23 locationsNCT03047369
Recruiting
Phase 2

Study of Olutasidenib and Temozolomide in HGG

Metastatic Brain TumorIDH1 MutationAstrocytoma, Grade IV+16 more
Rigel Pharmaceuticals60 enrolled18 locationsNCT06161974
Recruiting
Not Applicable

Coflex PS3 Actual Conditions for Use Study

Spinal Stenosis Lumbar
Xtant Medical300 enrolled19 locationsNCT02555280
Recruiting

Spinal Cord Injury Registry - North American Clinical Trials Network

Spinal Cord Injury
Robert G. Grossman, MD1,500 enrolled14 locationsNCT00178724