Phase 1 SURGICAL Clinical Trials
12 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–12 of 12 trials
Recruiting
Phase 1
A Study of Amicidin-β Topical Solution for Patients With Surgical or Traumatic Wound Infections
Surgical wound infectionTraumatic Wound Infection
Macro Biologics, Inc.44 enrolled4 locationsNCT07379684
Recruiting
Phase 1Phase 2
SNB-101 for Treatment of Extensive Stage Small Cell Lung Cancer
Patient is Not Suitable for Complete Surgical Resection With a Cytologically or Histologically Confirmed Small Cell Lung Cancer(SCLC)
SN BioScience55 enrolled1 locationNCT07391813
Recruiting
Phase 1Phase 2
Parathyroid Allotransplant for Treatment of Hypoparathyroidism
HypoparathyroidismHypoparathyroidism Post-surgicalHypoparathyroidism Postprocedural
Peter Stock3 enrolled1 locationNCT06961071
Recruiting
Phase 1
Regenn® Therapy System Safety Study
Surgical Wound
Progenerative Medical, Inc30 enrolled1 locationNCT06259409
Recruiting
Phase 1
Safety and Efficacy of Tissue Engineered Endothelial Keratoplasty
Fuchs' Endothelial DystrophyBullous KeratopathyMild to Moderate Corneal Endothelial Decompensation+1 more
Singapore Eye Research Institute30 enrolled1 locationNCT04319848
Recruiting
Phase 1
Comparison Between Epidural Analgesia and Intrathecal Opioid Analgesia for Pain Management in Open Nephrectomy
PainSurgical Procedure, UnspecifiedRenal Cancer
University Hospital of Split40 enrolled1 locationNCT06595329
Recruiting
Phase 1Phase 2
Effect of Dexmedetomidine on Hemodynamic Response to Endotracheal Intubation in Hypertensive Patients
Blood PressureElective Surgical PatientHypertensive Patients+2 more
Liaquat National Hospital & Medical College60 enrolled1 locationNCT06712186
Recruiting
Phase 1
Phenylephrine Tumescence for Hemostasis in Surgery for Burn Injury
Blood Loss, Surgical
University of Manitoba24 enrolled1 locationNCT01731444
Completed
Phase 1
A phase 1, Randomised, placebo-controlled, single-blind, single-ascending dose study, to determine the safety and tolerability of intravenous Gemini in healthy volunteers.
Post-surgical infection
Revelation Biosciences Sub Inc40 enrolled1 locationACTRN12624000137594
Completed
Phase 1
A pilot randomised open-label taste-testing study to evaluate the acceptability of chocolate-based midazolam in children
Children needing a sedating premedication prior to general anaesthesia for a surgical procedure
Princess Margaret Hospital150 enrolled1 locationACTRN12615000225516
Completed
Phase 1
A single dose, randomized, blinded, pilot, comparative assessment of the absorption of a generic formulation of tibolone tablet against the innovator tibolone tablet conducted in healthy female volunteers under fasting conditions
Pilot bioequivalence study conducted in healthy volunteers comparing two formulations of tibolone with no health condition or problem studied.
Although this study is being conducted in healthy volunteers who are not being treated for the condition to which the medicine is used, tibolone belongs to a class of medicines called synthetic steroid hormone drugs and is prescribed for the short-term treatment of symptoms due to natural or surgical menopause.
Zenith Technology Corporation Limited8 enrolled1 locationACTRN12613000943741
Completed
Phase 1
A study to define the pharmacokinetic properties of lignocaine gel applied topically on a surgical field
The effects of lignocaine on surgical wounds in laparoscopy or hysteroscopy
Medortus Inc12 enrolled1 locationACTRN12611001201965