Phase 4 SURGICAL Clinical Trials
39 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–20 of 39 trials
Recruiting
Phase 4
PeRiOperative Medicine Platform Trial
Quality of LifeAnaesthesiaSurgical Site Infection After Major Surgery+2 more
Monash University7,800 enrolled2 locationsNCT07186634
Recruiting
Phase 4
The Effect of Nocturnal Dexmedetomidine on Postoperative Sleep Quality and Fatigue After Major Surgery in Elderly Patients: DEXSLEEP Study
surgical stress responsePostoperative FatiguePostoperative Sleep Disturbances
Ziekenhuis Oost-Limburg102 enrolled1 locationNCT06480539
Recruiting
Phase 4
Intraperitoneal Infusion of Analgesic for Postoperative Pain Management
Pain, PostoperativeGynecologic Surgical ProceduresHysterectomy+1 more
Ying Liu120 enrolled2 locationsNCT04130464
Recruiting
Phase 4
Pre-Incision Peripheral Nerve Blocks for Lower Extremity Fracture Surgery in Older Adults
Orthopaedic traumaLower Extremity FractureSurgical Fracture Repair+1 more
University of Maryland, Baltimore34 enrolled1 locationNCT07217626
Recruiting
Phase 4
Duration of Cardiac Antimicrobial Prophylaxis Outcomes Study
Surgical Site Infection
Monash University9,180 enrolled27 locationsNCT05447559
Recruiting
Phase 4
Antibiotics for Prevention of Infection Following Orthognathic Surgery
Orthognathic Surgical Site Infection
Abdul El-Rabbany400 enrolled1 locationNCT05852158
Recruiting
Phase 4
Preoperative Clindamycin Vaginal Cream Versus Vaginal Cleansing With Povidone-iodine on Postoperative Infections After Cesarean Section
Infection Control / MethodsSurgical Site Infection (SSI)
Beni-Suef University150 enrolled1 locationNCT07474194
Recruiting
Phase 4
Reducing Perioperative Oxidative Stress to Prevent Postoperative Chronic Pain Following Total Knee Arthroplasty
Osteoarthritis, KneeTotal Knee ArthroplastyChronic Postsurgical Pain
Vanderbilt University Medical Center148 enrolled1 locationNCT06083480
Recruiting
Phase 4
Continuous Infusions vs Scheduled Bolus Infusions
Pain, PostoperativeSurgical Procedure, Unspecified
Stanford University240 enrolled1 locationNCT03230565
Recruiting
Phase 4
Efficacy of Prothrombin Complex Concentrate Reducing Perioperative Blood Loss in Cardiac Surgery
Cardiac Surgical Procedures
SHI Jia820 enrolled2 locationsNCT04244981
Recruiting
Phase 4
Paracervical Injection and Opioid Use After Vaginal Hysterectomy for Prolapse
Opioid UsePostoperative PainVaginal Hysterectomy+2 more
University of North Carolina, Chapel Hill56 enrolled1 locationNCT07213635
Recruiting
Phase 4
Treatment With Indapamide in Patients With Post-Surgical Hypoparathyroidism
Hypoparathyroidism Post-surgical
Lars Rejnmark24 enrolled1 locationNCT07034677
Recruiting
Phase 4
Different Dose Esketamine and Dexmedetomidine for Supplemental Analgesia and Longterm Outcomes
EsketamineDexmedetomidinepostoperative analgesia+2 more
Peking University First Hospital312 enrolled1 locationNCT06087510
Recruiting
Phase 4
Oliceridine on Postoperative Nausea and Vomiting in Gynecological Laparoscopic Surgery
laparoscopyGynecologic Surgical ProceduresPostoperative Nausea and Vomiting (PONV)
YanYing Xiao96 enrolled1 locationNCT07026162
Recruiting
Phase 4
Decolonization to Reduce After-Surgery Events of Surgical Site Infection
Surgical Site Infection
University of California, Irvine2,700 enrolled4 locationsNCT05586776
Recruiting
Phase 4
Ostomy Primary Closure With 0.1% Betaine/Polyhexanide Wound Irrigation Compared to Pursestring Closure
Colorectal DisordersSurgical Site InfectionWound Surgical
University of Nevada, Las Vegas84 enrolled1 locationNCT06309368
Recruiting
Phase 4
Population Pharmacokinetics and Pharmacogenomics of Oral Oxycodone in Pediatric Surgical Patients
Pediatric Surgical Patient
Boston Children's Hospital68 enrolled1 locationNCT02044497
Recruiting
Phase 4
Nebulized Versus Intravenous Tranexamic Acid on Surgical Field Quality in Patients Undergoing Endoscopic Sinus Surgeries
IntravenousSurgical FieldNebulization+1 more
Cairo University60 enrolled1 locationNCT06777966
Recruiting
Phase 4
Opioid Free Anesthesia-Analgesia Strategy and Surgical Stress in Elective Open Abdominal Aortic Aneurysm Repair
Opioid UsePostoperative PainAnesthesia+5 more
University of Crete40 enrolled1 locationNCT04894864
Recruiting
Phase 4
The Effect of Local Application of Tranexamic Acid Versus Placebo on Postoperative Complications in Plastic Surgery
Surgical Complication
St. Olavs Hospital3,000 enrolled1 locationNCT06270407