Phase 2 Symptom Clinical Trials
39 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 39 trials
Recruiting
Phase 2
Mindfulness Engaged Neurostimulation for Depression (MEND II)
DepressionDepressive DisorderDepressive Symptoms+2 more
University of California, San Diego120 enrolled1 locationNCT07512284
Recruiting
Phase 2
Novel Use of Probenecid to Alleviate Symptoms of Opioid Withdrawal
Chronic PainDrug Dependence of Morphine TypeSymptom, Withdrawal
University of Calgary40 enrolled1 locationNCT04939623
Recruiting
Phase 1Phase 2
Study Evaluating ABCL635 for Vasomotor Symptoms of Menopause
Healthy VolunteersVasomotor Symptoms Associated With Menopause
AbCellera Biologics Inc.136 enrolled13 locationsNCT07118891
Recruiting
Phase 2Phase 3
A Study of the Efficacy and Safety of Danicamtiv in Participants With Symptomatic Genetic and Familial Dilated Cardiomyopathy
Symptomatic Genetic Dilated Cardiomyopathy
Kardigan, Inc.332 enrolled33 locationsNCT07210723
Recruiting
Phase 2
Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression
DepressionDepressive DisorderMolecular Mechanisms of Pharmacological Action+10 more
National Institute of Mental Health (NIMH)50 enrolled1 locationNCT06511908
Recruiting
Phase 1Phase 2
Study of Cord Blood Derived Mesenchymal Stem Cells for Treatment of Moderate, Severe or Critical Pneumonia
Malignant Solid NeoplasmHematopoietic and Lymphoid Cell NeoplasmCOVID-19 Infection+2 more
M.D. Anderson Cancer Center70 enrolled1 locationNCT04565665
Recruiting
Phase 2Phase 3
A Study to Evaluate the Effect of Aficamten in Pediatric Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM).
PediatricSymptomatic Obstructive Hypertrophic Cardiomyopathy
Cytokinetics55 enrolled38 locationsNCT06412666
Recruiting
Phase 2
Hippocampus-Protective Radiotherapy Combined With Osimertinib for Symptomatic Brain Metastases in EGFR-Mutated Lung Cancer
Naive Advanced Non-small Cell Lung Cancer With EGFR-sensitive Mutations (EGFR Exon 19 Deletion and Exon 21 L858R Mutation) and Symptomatic Brain Metastases
Tianjin Medical University Cancer Institute and Hospital74 enrolled1 locationNCT07505173
Recruiting
Phase 2
New Treatment Strategies and Epigenetic Biomarker for Management of Benign Prostatic Hyperplasia
Lower Urinary Track SymptomsBPH (Benign Prostatic Hyperplasia)
Beth Israel Deaconess Medical Center242 enrolled1 locationNCT06944145
Recruiting
Phase 2
Proof-of-Concept Trial to Assess the Efficacy and Safety of Fezolinetant in Improving Vasomotor Symptoms in Men With Prostate Cancer Undergoing Androgen Deprivation Therapy
Prostate CancerProstate CarcinomaProstate Neoplasm+15 more
Shehzad Basaria, M.D.60 enrolled1 locationNCT06957691
Recruiting
Phase 2
Personalized Brain Stimulation to Treat Chronic Concussive Symptoms
DepressionAnxietyDysautonomia+9 more
University of California, Los Angeles75 enrolled1 locationNCT06073886
Recruiting
Phase 1Phase 2
A Basket Clinical Study to Assess Glycerol Tributyrate in Patients With Mitochondrial Encephalopathy, Lactic Acidosis, Stroke-like Episodes (MELAS) or Leber's Hereditary Optic Neuropathy-Plus (LHON-Plus)
MELAS SyndromeLebers Hereditory Optic Neuropathy With Extra Ocular Symptoms (LHON-Plus)
George Washington University24 enrolled1 locationNCT06792500
Recruiting
Phase 2
Cannabidiol for Reduction of Brain Neuroinflammation
Depressive SymptomsBack Pain
Massachusetts General Hospital80 enrolled1 locationNCT05066308
Recruiting
Phase 2
Treatment of Presymptomatic (Stage 1) Type 1 Diabetes Pediatric Patients With Treg Cell Preparations and Anti-CD20 Antibody
Diabetes Mellitus, Type 1Presymptomatic Diabetes Type 1 (Stage 1)Diabetes Mellitus, Type I
PolTREG S.A.150 enrolled8 locationsNCT06688331
Recruiting
Phase 2
AMBER-HFpEF: Assessment of CK-4021586 in a Multi-Center, Blinded Evaluation of Safety and Tolerability Results in HFpEF
Symptomatic Heart Failure With Preserved Ejection Fraction (HFpEF)
Cytokinetics60 enrolled24 locationsNCT06793371
Recruiting
Phase 1Phase 2
Safety and Efficacy of Lyophilized Fecal Microbiota Transplantation Via Capsules for Intestinal Multidrug-resistant Bacteria Decolonization
Colonization, Asymptomatic
University of Rijeka48 enrolled1 locationNCT07106580
Recruiting
Phase 2
Safety and Efficacy of Asimadoline (TP0052) in Patients With Vasomotor Symptoms (VMS).
Vasomotor Symptoms
Tioga Pharmaceuticals120 enrolled1 locationNCT07042516
Recruiting
Phase 2
Study of Dextromethorphan in OCD and Related Disorders
Obsessive-Compulsive DisorderSomatic Symptom DisorderIllness Anxiety Disorder+1 more
Stanford University60 enrolled1 locationNCT04899687
Recruiting
Phase 2Phase 3
Efficacy of Tadalafil (5mg) For Treatment of Early Storage Symptoms and Erectile Dysfunction After Endoscopic Enucleation of Prostate
Erectile DysfunctionLower Urinary Tract Symptoms
Mansoura University110 enrolled1 locationNCT05955001
Recruiting
Phase 2
Testing MitoQ on Lower Urinary Tract Symptoms in Older Women With Metabolic Syndrome
Lower Urinary Tract SymptomsOveractive Bladder Syndrome
Iman Al-Naggar, PhD50 enrolled1 locationNCT06351683