Phase 1 Synovial Sarcoma Clinical Trials

11 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 111 of 11 trials

Recruiting
Phase 1Phase 2

Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed).

ParagangliomaPheochromocytomaSolid Tumor Cancer+19 more
Fundación de investigación HM25 enrolled1 locationNCT06607692
Recruiting
Phase 1

A Study to Test the Safety, Tolerability and Effect of ZI-MA4-1 for Patients With Locally Advanced or Metastatic Solid Malignancies

Ovarian CancerHead and Neck CancerSynovial Sarcomas+1 more
Zelluna Immunotherapy AS9 enrolled2 locationsNCT07613723
Recruiting
Phase 1

Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced Sarcoma

Metastatic SarcomaMetastatic LeiomyosarcomaUnresectable Leiomyosarcoma+9 more
National Cancer Institute (NCI)30 enrolled16 locationsNCT05711615
Recruiting
Phase 1

START: Safety and Anti-Tumor Activity of PeptiCRAd-1 in Treatment of Cancer

Triple-Negative Breast CancerColorectal, CancerSarcoma+5 more
Valo Therapeutics Oy15 enrolled7 locationsNCT05492682
Recruiting
Phase 1Phase 2

Personalized Vaccination in Fusion+ Sarcoma Patients (PerVision)

Ewing SarcomaRhabdomyosarcomaSynovial Sarcoma
University Hospital Tuebingen30 enrolled4 locationsNCT06094101
Recruiting
Phase 1

Phase I/Ib Study of NK Expressing an Affinity-enhanced T-cell Receptor (TCR) Against the NY-ESO-1

Synovial SarcomaMyxoid/Round Cell Liposarcoma
M.D. Anderson Cancer Center44 enrolled1 locationNCT06083883
Recruiting
Phase 1Phase 2

Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors

OsteosarcomaEwing SarcomaNeuroblastoma+10 more
University of Florida27 enrolled1 locationNCT06625190
Recruiting
Phase 1Phase 2

SPEARHEAD-3 Pediatric Study

OsteosarcomaSynovial SarcomaMalignant Peripheral Nerve Sheath Tumor (MPNST)+1 more
USWM CT, LLC20 enrolled10 locationsNCT05642455
Recruiting
Phase 1

HER2 Chimeric Antigen Receptor (CAR) T Cells in Combination With Checkpoint Blockade in Patients With Advanced Sarcoma

Soft Tissue SarcomaSarcomaOsteosarcoma+5 more
Baylor College of Medicine25 enrolled1 locationNCT04995003
Recruiting
Phase 1

ACTengine® IMA203 Combined With mRNA-4203

Cutaneous MelanomaSynovial Sarcoma
Immatics US, Inc.15 enrolled4 locationsNCT06946225
Recruiting
Phase 1

AOH1996 for the Treatment of Refractory Solid Tumors

Pancreatic CancerOvarian CancerNon-small Cell Lung Cancer+4 more
City of Hope Medical Center92 enrolled2 locationsNCT05227326