Phase 2 T Cell Clinical Trials

43 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 43 trials

Recruiting
Phase 2

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

Stage IV Renal Cell Cancer AJCC v8Stage IVB Prostate Cancer AJCC v8Large Cell Neuroendocrine Carcinoma+42 more
National Cancer Institute (NCI)314 enrolled579 locationsNCT03866382
Recruiting
Phase 2

A Clinical Trial to Investigate 18F-AzaFol in the Diagnosis of Large Vessel Vasculitis

Giant Cell Arteritis
Insel Gruppe AG, University Hospital Bern70 enrolled1 locationNCT06335888
Recruiting
Phase 2

Photopheresis in Early-stage Mycosis Fungoides

Mycosis FungoidesCutaneous T Cell Lymphoma
Columbia University74 enrolled1 locationNCT05680558
Recruiting
Phase 2

(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis

Advanced Systemic Mastocytosis (AdvSM)SM With an Associated Hematologic Neoplasm (SM-AHN)Mast Cell Leukemia (MCL)+1 more
Cogent Biosciences, Inc.140 enrolled42 locationsNCT04996875
Recruiting
Phase 2

Study of Lacutamab in Peripheral T-cell Lymphoma

Relapse/RecurrencePeripheral T Cell Lymphoma
The Lymphoma Academic Research Organisation56 enrolled64 locationsNCT04984837
Recruiting
Phase 2

Study of Pimicotinib in Japanese Participants With Tenosynovial Giant Cell Tumor (TGCT) (J-MANEUVER)

Tenosynovial Giant Cell Tumor
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany20 enrolled1 locationNCT07499362
Recruiting
Phase 1Phase 2

Combination of Mitoxantrone Liposome and Etoposide, Dexamethasone, Pegaspargase and Golidocitinib (MEPL-G) in the Treatment of NK/T-cell Lymphoma Associated Hemophagocytic Lymphohistiocytosis (NKTCL-HLH)

Extranodal NK T Cell LymphomaHemophagocytic Lymphohistiocytosis (HLH)
Beijing Tongren Hospital25 enrolled1 locationNCT07525466
Recruiting
Phase 2

Tocilizumab Discontinuation Versus Dose Reduction for Patients With Well-Controlled Giant Cell Arteritis

Giant Cell Arteritis (GCA)
National Institute of Allergy and Infectious Diseases (NIAID)78 enrolled7 locationsNCT07108387
Recruiting
Phase 2

Exploratory Clinical Study of SHR-0302 and SHR-2554 in Patients With Relapsed/Refractory Peripheral T Cell Lymphoma

Relapsed/Refractory Peripheral T Cell Lymphoma
Fudan University25 enrolled1 locationNCT06519526
Recruiting
Phase 2

Topical Ketotifen 0.25% for Secondary Vestibulodynia

VulvodyniaProvoked VestibulodyniaSecondary Provoked Vestibulodynia+4 more
Center for Vulvovaginal Disorders54 enrolled3 locationsNCT07257029
Recruiting
Phase 1Phase 2

A Study to Investigate Safety and Effectiveness of Porcine Pancreatic Cells (OPF-310) in Patients With Type 1 Diabetes Mellitus

Metabolic DiseaseDiabetes Mellitus, Type 1Type 1 Diabetes+14 more
Otsuka Pharmaceutical Factory, Inc.13 enrolled1 locationNCT06575426
Recruiting
Phase 1Phase 2

A First-in-Human Study of HLA-Partially to Fully Matched Allogenic Cryopreserved Deceased Donor Bone Marrow Transplantation for Patients With Hematologic Malignancies

Acute Lymphoblastic LeukemiaAcute Myeloid LeukemiaAcute Leukemia+8 more
Ossium Health, Inc.12 enrolled9 locationsNCT05589896
Recruiting
Phase 1Phase 2

Phase 1/2 Dose Finding, Safety and PK Study in Advanced Refractory Solid Tumors

Breast CancerProstate Cancer Castration-resistant Prostate CancerColo-rectal Cancer+2 more
MBrace Therapeutics150 enrolled7 locationsNCT07145255
Recruiting
Phase 2

A Phase II, Single-center, Single-arm Study Evaluating the Safety and Efficacy of Golidocitinib in the Management of Newly Diagnosed Peripheral T Cell Lymphoma Patients (GOLDEN Study) and Correlative Study

Peripheral T Cell Lymphoma
M.D. Anderson Cancer Center30 enrolled1 locationNCT06630091
Recruiting
Phase 1Phase 2

A Platform Trial Evaluating New Drugs or Combination in R/R Peripheral T-cell Lymphomas

Peripheral T Cells Lymphoma (PTCL)
The Lymphoma Academic Research Organisation49 enrolled20 locationsNCT07018752
Recruiting
Phase 2

Alpha/Beta TCD HCT in Patients With Inherited BMF Disorders

Dyskeratosis CongenitaFanconi AnemiaMyelodysplastic Syndromes+5 more
Masonic Cancer Center, University of Minnesota48 enrolled1 locationNCT03579875
Recruiting
Phase 2Phase 3

A Clinical Trial of Cidabenamine Plus Azacitidine to Prevent Post-Transplant Progression in High-Risk Peripheral T-Cell Lymphoma

Peripheral T Cell Lymphoma
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine40 enrolled1 locationNCT07389616
Recruiting
Phase 1Phase 2

Evaluate the Safety and Clinical Activity of HH2853

Advanced Solid TumorPeripheral T Cell LymphomaFL Lymphoma+1 more
Haihe Biopharma Co., Ltd.254 enrolled25 locationsNCT04390737
Recruiting
Phase 2

Zeprumetostat, Azacitidine Combined With Lipo-MIT in R/R PTCL

Peripheral T Cells Lymphoma (PTCL)
The First Affiliated Hospital of Soochow University26 enrolled1 locationNCT07372352
Recruiting
Phase 2

Dapagliflozin and Endothelin Receptor Antagonism in Large Vessel Vasculitis (DERAIL-LVV)

Giant Cell Arteritis (GCA)Takayasu ArteritisLarge Vessel Vasculitis
University of Edinburgh60 enrolled1 locationNCT06887062