Phase 2 TEN Clinical Trials

219 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 219 trials

Recruiting
Phase 2Phase 3

Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial

Extensive Stage Lung Small Cell Carcinoma
National Cancer Institute (NCI)138 enrolled415 locationsNCT04402788
Recruiting
Phase 2

Phase II Study of Platinum/Etoposide Plus Ivonescimab for Extensive-Stage Small Cell Lung Cancer

Extensive Stage Lung Small Cell Cancer
PrECOG, LLC.60 enrolled5 locationsNCT07057791
Recruiting
Phase 2

Spironolactone for Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension
National Institutes of Health Clinical Center (CC)70 enrolled1 locationNCT01712620
Recruiting
Phase 2

A Study to Learn About the Study Medicine (Called PF-07868489) in People With Pulmonary Arterial Hypertension Who Have Previously Participated in a Clinical Study With PF-07868489

Pulmonary Hypertension
Pfizer36 enrolled44 locationsNCT07073820
Recruiting
Phase 1Phase 2

A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)

Healthy Volunteers, Pulmonary Arterial Hypertension
Novartis Pharmaceuticals232 enrolled85 locationsNCT06649110
Recruiting
Phase 2Phase 3

Shorter and Safer Treatment Regimens for Latent TB

Tuberculosis Infection, Latent
McGill University Health Centre/Research Institute of the McGill University Health Centre1,800 enrolled13 locationsNCT06498414
Recruiting
Phase 2

A Study to Identify an Optimal Dose of QCZ484 in Mild to Moderate Hypertensive Patients

Hypertension
Novartis Pharmaceuticals380 enrolled84 locationsNCT06857955
Recruiting
Phase 2

Lysergic Acid Diethylamide (LSD) in Palliative Care

PainQuality of LifePsychological Distress+7 more
University Hospital, Basel, Switzerland60 enrolled4 locationsNCT05883540
Recruiting
Phase 1Phase 2

A Clinical Study of Gocatamig (MK-6070) and Infinatamab Deruxtecan (MK-2400) in People With Small Cell Lung Cancer (MK-6070-003)

Small Cell Lung Cancer Extensive Stage
Merck Sharp & Dohme LLC170 enrolled15 locationsNCT07227597
Recruiting
Phase 2

A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension

Uncontrolled Hypertension
Retension Pharmaceuticals. Inc.280 enrolled20 locationsNCT07142356
Recruiting
Phase 2

Tislelizumab Combined With Chemotherapy and Thoracic Radiotherapy in ES-SCLC

Extensive-stage Small-cell Lung Cancer
Second Hospital of Shanxi Medical University40 enrolled6 locationsNCT06536868
Recruiting
Phase 2

A Study of Mosliciguat in Combination With Inhaled Treprostinil in PH-ILD

Cardiovascular DiseasesFibrosisLung Diseases+3 more
Pulmovant, Inc.20 enrolled1 locationNCT07333183
Recruiting
Phase 1Phase 2

Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung Cancer

Stage IV Lung Cancer AJCC v8Extensive Stage Lung Small Cell Carcinoma
National Cancer Institute (NCI)45 enrolled43 locationsNCT06287775
Recruiting
Phase 2

A Trial of Tarlatamab in Patients With Pretreated Extensive-stage Small Cell Lung Cancer (ES-SCLC) and ECOG PS 2

Extensive Stage Lung Small Cell Cancer
ETOP IBCSG Partners Foundation48 enrolled19 locationsNCT07203053
Recruiting
Phase 2

Study to Evaluate Sotatercept (MK-7962) in Children With Pulmonary Arterial Hypertension (PAH) (MK-7962-008)

Pulmonary Arterial Hypertension
Merck Sharp & Dohme LLC42 enrolled35 locationsNCT05587712
Recruiting
Phase 1Phase 2

Feasibility of Semaglutide in Advanced Lung Disease

ObesityChronic Obstructive Pulmonary DiseaseInterstitial Lung Disease+2 more
University of Pennsylvania8 enrolled1 locationNCT05746039
Recruiting
Phase 2

Neurocognitive Mechanisms Underlying Smartphone-Assisted Prevention of Relapse in Opioid Use Disorder

Magnetic Resonance ImagingEcological Momentary AssessmentAttentional Bias+4 more
University of Arkansas255 enrolled1 locationNCT05336188
Recruiting
Phase 2

Fentanyl Versus Hydromorphone in Patients on Mechanical Ventilation

Mechanical VentilationSedation and AnalgesiaCritical Care, Intensive Care
Beth Israel Deaconess Medical Center300 enrolled1 locationNCT07224620
Recruiting
Phase 2

Study of Pimicotinib in Japanese Participants With Tenosynovial Giant Cell Tumor (TGCT) (J-MANEUVER)

Tenosynovial Giant Cell Tumor
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany20 enrolled1 locationNCT07499362
Recruiting
Phase 2

A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis

Aortic Stenosis
Novartis Pharmaceuticals502 enrolled139 locationsNCT05646381