Phase 2 TEN Clinical Trials

266 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 266 trials

Recruiting
Phase 2Phase 3

Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial

Extensive Stage Lung Small Cell Carcinoma
National Cancer Institute (NCI)138 enrolled416 locationsNCT04402788
Recruiting
Phase 2

Study of Pimicotinib in Japanese Participants With Tenosynovial Giant Cell Tumor (TGCT) (J-MANEUVER)

Tenosynovial Giant Cell Tumor
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany20 enrolled3 locationsNCT07499362
Recruiting
Phase 1Phase 2

A Study to Evaluate DJI136, a DLL3-targeted CAR-T Therapy

Extensive-stage Small Cell Lung Cancer (ES-SCLC)
Novartis Pharmaceuticals80 enrolled3 locationsNCT07564401
Recruiting
Phase 2

A Phase II Clinical Trial of Efficacy and Safety of SAL0140 at Different Doses in Patients With Uncontrolled Hypertension

Uncontrolled Hypertension
Shenzhen Salubris Pharmaceuticals Co., Ltd.252 enrolled1 locationNCT07654140
Recruiting
Phase 2

Phase II Study of Platinum/Etoposide Plus Ivonescimab for Extensive-Stage Small Cell Lung Cancer

Extensive Stage Lung Small Cell Cancer
PrECOG, LLC.60 enrolled7 locationsNCT07057791
Recruiting
Phase 1Phase 2

Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung Cancer

Stage IV Lung Cancer AJCC v8Extensive Stage Lung Small Cell Carcinoma
National Cancer Institute (NCI)45 enrolled43 locationsNCT06287775
Recruiting
Phase 1Phase 2

A Clinical Study of Gocatamig (MK-6070) and Infinatamab Deruxtecan (MK-2400) in People With Small Cell Lung Cancer (MK-6070-003)

Small Cell Lung Cancer Extensive Stage
Merck Sharp & Dohme LLC170 enrolled31 locationsNCT07227597
Recruiting
Phase 2

A Study to Evaluate ALN-AGT01 RVR in Adult Patients With Mild to Moderate Hypertension Pretreated With Zilebesiran

Hypertension
Alnylam Pharmaceuticals93 enrolled3 locationsNCT07553442
Recruiting
Phase 1Phase 2

Post-operative Urinary Retention (POUR) Following Thoracic Surgery

Urinary Retention
Hackensack Meridian Health127 enrolled1 locationNCT03609580
Recruiting
Phase 2

A Trial of Tarlatamab in Patients With Pretreated Extensive-stage Small Cell Lung Cancer (ES-SCLC) and ECOG PS 2

Extensive Stage Lung Small Cell Cancer
ETOP IBCSG Partners Foundation48 enrolled19 locationsNCT07203053
Recruiting
Phase 2

Impact of Local Tissue Inflammation on Intramyocardial Conduction Pathways Post Percutaneous Valve : Evaluation by Positron Emission Tomography on Exploratory Cohort

Aortic Valve Stenosis
University Hospital, Brest100 enrolled1 locationNCT05308888
Recruiting
Phase 2

Spironolactone for Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension
National Institutes of Health Clinical Center (CC)70 enrolled1 locationNCT01712620
Recruiting
Phase 2

Chemo-Immunotherapy Followed by Durvalumab and Ceralasertib in Treatment Naïve Patients With Extensive Stage Small Cell Lung Cancer

Extensive-stage Small-cell Lung Cancer
Muhammad Furqan30 enrolled5 locationsNCT04699838
Recruiting
Phase 2

Maintenance Lurbinectedin in Combination With Serplulimab for Patients With ES-SCLC

Extensive-stage Small-cell Lung Cancer
Guangzhou Institute of Respiratory Disease30 enrolled1 locationNCT06497530
Recruiting
Phase 2

Take the Reins: The Effects of Nutrient Timing on Cancer-related Fatigue

SurvivorshipNeoplasmsFatigue+3 more
University of Maryland, Baltimore96 enrolled1 locationNCT06482515
Recruiting
Phase 2

Preoperative IMRT With Anlotinib and Penpulimab for Localized Sarcoma (SPARE-01)

Sarcoma,Soft TissueAnlotinibIntensity Modulated Radiotherapy+3 more
Cancer Institute and Hospital, Chinese Academy of Medical Sciences30 enrolled1 locationNCT05167994
Recruiting
Phase 2

Using Mobile Stress Management to Reduce Hypertension in African American Men

Hypertension
ISA Associates, Inc.135 enrolled1 locationNCT07594808
Recruiting
Phase 2

Adjunctive Fludrocortisone in Septic Shock

SepsisSeptic ShockSepsis and septic shock+2 more
Chinese University of Hong Kong32 enrolled5 locationsNCT07451886
Recruiting
Phase 2Phase 3

Bedaquiline Roll-out Evidence in Contacts and People Living With HIV to Prevent TB

Tuberculosis, Latent
Johns Hopkins University2,530 enrolled6 locationsNCT06568484
Recruiting
Phase 1Phase 2

Quaratusugene Ozeplasmid (Reqorsa) and Atezolizumab Maintenance Therapy in ES-SCLC Patients

Small Cell Lung Cancer Extensive Stage
Genprex, Inc.62 enrolled17 locationsNCT05703971