Phase 3 TEN Clinical Trials

173 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 120 of 173 trials

Recruiting
Phase 3

A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure

Chronic Kidney Disease and Hypertension
AstraZeneca5,000 enrolled759 locationsNCT06742723
Recruiting
Phase 2Phase 3

Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial

Extensive Stage Lung Small Cell Carcinoma
National Cancer Institute (NCI)138 enrolled415 locationsNCT04402788
Recruiting
Phase 3

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

Cardiovascular DiseasesHypertensionDiabetes Mellitus, Type 2
Boehringer Ingelheim11,800 enrolled1152 locationsNCT07064473
Recruiting
Phase 3

Intra-arterial Tenecteplase for Acute Medium Vessel Occlusion Stroke

Ischemic StrokeMedium Vessel OcclusionEndovascular Treatment+1 more
Beijing Tiantan Hospital488 enrolled1 locationNCT07357987
Recruiting
Phase 2Phase 3

Shorter and Safer Treatment Regimens for Latent TB

Tuberculosis Infection, Latent
McGill University Health Centre/Research Institute of the McGill University Health Centre1,800 enrolled13 locationsNCT06498414
Recruiting
Phase 3

Tranexamic Acid in Adult Spinal Deformity Surgery

Blood Loss, SurgicalSpinal DeformityDegenerative Lumbar Spinal Stenosis
Hospital for Special Surgery, New York100 enrolled1 locationNCT03553186
Recruiting
Phase 3

Lumbar Steroid Use in Patients Undergoing Posterior Lumbar Decompression

Opioid UsePain, PostoperativePain, Back+1 more
Hospital for Special Surgery, New York150 enrolled1 locationNCT05058287
Recruiting
Phase 3

Clinical Trial to Evaluate the Efficacy and Safety of Monotherapy Group of HL1113R1 or HL1113R2 Versus HL1113 (Fixed Dose Combination) in Patients With Essential Hypertension and Type II Diabetes Mellitus

HypertensionDiabete Type 2
Hanlim Pharm. Co., Ltd.228 enrolled1 locationNCT07552389
Recruiting
Phase 3

A Master Protocol for Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight: (ATTAIN-Hypertension Screening)

Hypertension
Eli Lilly and Company974 enrolled100 locationsNCT06948422
Recruiting
Phase 3

A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL1

HypertensionOverweight or Obesity
Eli Lilly and Company487 enrolled99 locationsNCT06948435
Recruiting
Phase 3

A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)

Pulmonary Arterial Hypertension
Merck Sharp & Dohme LLC815 enrolled93 locationsNCT07218029
Recruiting
Phase 3

Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

HypertensionHigh Risk Cardiovascular DiseaseHigh Cardiovascular Risk
Alnylam Pharmaceuticals11,000 enrolled597 locationsNCT07181109
Recruiting
Phase 3

A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL2

Hypertension
Eli Lilly and Company487 enrolled99 locationsNCT06952530
Recruiting
Phase 3

Efficacy and Safety Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)

Interstitial Lung DiseasePulmonary Hypertension
Insmed Incorporated344 enrolled68 locationsNCT07179380
Recruiting
Phase 3

Prevention of Intradialytic Hypotension by Inhibiting Bradykinin B2 Receptor

Intradialytic Hypotension
Vanderbilt University Medical Center26 enrolled1 locationNCT05834777
Recruiting
Phase 3

A Study Providing Treatment Access in Participants With Pulmonary Hypertension Completing a Parent Study and Having no Other Option

Hypertension, Pulmonary
Actelion280 enrolled45 locationsNCT05179876
Recruiting
Phase 2Phase 3

Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study

Moderate Aortic Valve Stenosis
Kardigan, Inc.1,276 enrolled70 locationsNCT07001800
Recruiting
Phase 2Phase 3

PRECISION-BP: Precision Chronopharamacotherapy Targeting NP-RAAS-BP Rhythm Axis

ObesityCardiovascular DiseasesHypertension+3 more
University of Alabama at Birmingham160 enrolled1 locationNCT04971720
Recruiting
Phase 3

Bevacizumab Plus FSRT Versus Hippocampus-Avoidant WBRT in Lung Adenocarcinoma With Extensive Brain Metastases

Brain MetastasesLung AdenocarcinomaWhole-Brain Radiotherapy+2 more
Sun Yat-sen University220 enrolled3 locationsNCT07481786
Recruiting
Phase 3

Intranasal Dexmedetomidine on Blood Pressure in Elderly Hypertensive Patients Undergoing Cataract Surgery

HypertensionCataract
Suez Canal University126 enrolled1 locationNCT07080229