THA Clinical Trials in Boston, Massachusetts

15 recruitingBoston, Massachusetts

Showing 115 of 15 trials

Recruiting
Phase 3

A Study to Evaluate Long-term Safety in Participants Who Have Participated in Other Luspatercept (ACE-536) Clinical Trials

Beta-ThalassemiaMyelodysplastic Syndromes (MDS)Myeloproliferative Neoplasm(MPN)-Associated Myelofibrosis
Celgene665 enrolled143 locationsNCT04064060
Recruiting
Phase 2

A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma

GerminomaBasal Ganglia GerminomaDiabetes Insipidus+3 more
Children's Oncology Group240 enrolled109 locationsNCT06368817
Recruiting
Phase 3

Romosozumab as an Adjunct to Physiologic Estrogen Replacement in Functional Hypothalamic Amenorrhea

FHA (Functional Hypothalamic Amenorrhea)
Massachusetts General Hospital114 enrolled2 locationsNCT06533865
Recruiting
Phase 3

A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia

Sickle Cell DiseaseThalassemia
Novo Nordisk A/S480 enrolled103 locationsNCT06609226
Recruiting
Phase 3

Investigating an mRNA CAR T-cell Therapy, Known as Descartes-08, as a Potential Approach to Treat Myasthenia Gravis

Myasthaenia Gravis
Cartesian Therapeutics100 enrolled34 locationsNCT06799247
Recruiting
Phase 3

A Trial of Setmelanotide in Patients With Congenital Hypothalamic Obesity (Sub-study of NCT05774756)

Hypothalamic ObesityMultiple Pituitary Hormone Deficiency Genetic FormSepto-Optic Dysplasia+3 more
Rhythm Pharmaceuticals, Inc.39 enrolled11 locationsNCT06760546
Recruiting

Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated Anomalies

Facial PalsyCongenital Fibrosis of Extraocular MusclesDuane Retraction Syndrome+23 more
Boston Children's Hospital20,000 enrolled1 locationNCT03059420
Recruiting
Phase 1

Hematopoietic Stem Cell BCL11A Enhancer Gene Editing for Severe β-Hemoglobinopathies

Beta-ThalassemiaSickle Cell DiseaseSickle Cell Anemia (HbSS, or HbSβ-thalassemia0)+1 more
Daniel Bauer10 enrolled1 locationNCT06647979
Recruiting

ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

ThrombophiliaThrombosisSickle Cell Disease+10 more
American Thrombosis and Hemostasis Network3,000 enrolled71 locationsNCT04398628
Recruiting
Phase 2

Kisspeptin Administration Subcutaneously to Patients With Hypothalamic Amenorrhea

Hypogonadotropic HypogonadismHypothalamic Amenorrhea
Stephanie B. Seminara, MD20 enrolled1 locationNCT07224438
Recruiting
Phase 1Phase 2

A Study of RM-718 in Healthy Subjects and Patients With MC4R Pathway Impairment

Prader-Willi SyndromeHypothalamic ObesityPWS
Rhythm Pharmaceuticals, Inc.150 enrolled7 locationsNCT06239116
Recruiting

Cerebral/ Cortical Visual Impairment: Screening, Identification and Outcome Prediction in Neonates

Preterm Less Than 32wks With IVH, WMI/PVLLate Preterm or Term (37-42wks) With Neonatal Encephalopathy Treated With Hypothermia for HIE
Brigham and Women's Hospital60 enrolled1 locationNCT07275021
Recruiting
Phase 2

Study of Olutasidenib and Temozolomide in HGG

Metastatic Brain TumorIDH1 MutationAstrocytoma, Grade IV+16 more
Rigel Pharmaceuticals60 enrolled18 locationsNCT06161974
Recruiting

Study of the Role of Genetic Modifiers in Hemoglobinopathies

Sickle Cell DiseaseHemoglobinopathiesThalassemia Alpha+1 more
Cyprus Institute of Neurology and Genetics30,000 enrolled26 locationsNCT05799118
Recruiting

Orphan Europe Carbaglu® Surveillance Protocol

N-acetylglutamate Synthase (NAGS) Deficiency
Nicholas Ah Mew30 enrolled3 locationsNCT03409003