Phase 1 Thrombocytopenia Clinical Trials
20 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 20 trials
Recruiting
Phase 1Phase 2
A Study of Pirtobrutinib in Participants With Immune Thrombocytopenia
Immune Thrombocytopenia (ITP)
Eli Lilly and Company58 enrolled45 locationsNCT06721013
Recruiting
Phase 1
Phase 1b Trial of RAY121 in Immunological Diseases (RAINBOW Trial)
Antiphospholipid Syndrome (APS)Immune-mediated Necrotizing Myopathy (IMNM)Immune Thrombocytopenia (ITP)+3 more
Chugai Pharmaceutical144 enrolled69 locationsNCT06371417
Recruiting
Phase 1Phase 2
A Phase 1b/2a Study of Budoprutug in Subjects With Immune Thrombocytopenia (ITP)
ITPImmune Thrombocytopenia (ITP)Monoclonal+2 more
Climb Bio, Inc.24 enrolled20 locationsNCT07043946
Recruiting
Phase 1Phase 2
A Study to Evaluate the Safety and Efficacy of PN20 in the Treatment of Thrombocytopenia in Patients With Chronic Liver Disease Undergoing an Elective Procedure
Thrombocytopenia Associated With Chronic Liver Disease
Chongqing Peg-Bio Biopharm Co., Ltd.54 enrolled8 locationsNCT07446491
Recruiting
Phase 1
Study of PN20 in Adult Patients With Primary Immune Thrombocytopenia (ITP)
Primary Immune Thrombocytopenia (ITP)
Chongqing Peg-Bio Biopharm Co., Ltd.12 enrolled5 locationsNCT06880081
Recruiting
Phase 1
CAR T-cell Therapy Targeting CD19 and BCMA(QT-019C) in Patients With Relapse/Refractory Autoimmune Diseases
ANCA Associated Vasculitis (AAV)SLE - Systemic Lupus ErythematosusSSc-Systemic Sclerosis+3 more
Institute of Hematology & Blood Diseases Hospital, China12 enrolled1 locationNCT07315087
Recruiting
Phase 1Phase 2
A Phase Ib/II Clinical Trial of Multiple Doses of STSA-1301 Subcutaneous Injection in Healthy Subjects and Patients With Immune Thrombocytopenia (ITP)
Primary Immune Thrombocytopenia (ITP)
Jiangsu BioJeTay Biotechnology Co., Ltd.56 enrolled7 locationsNCT06929299
Recruiting
Phase 1Phase 2
A Study of CM336 in Patients With Relapsed or Refractory Autoimmune Cytopenia
Autoimmune Hemolytic AnemiaEvans SyndromeAutoimmune Cytopenia+1 more
Keymed Biosciences Co.Ltd158 enrolled3 locationsNCT07175493
Recruiting
Phase 1
Phase I Study of SHR-2173 Injection in Patients With Primary Immune Thrombocytopenia
Immune Thrombocytopenia
Guangdong Hengrui Pharmaceutical Co., Ltd10 enrolled1 locationNCT07206758
Recruiting
Phase 1
OM336 in Autoimmune Cytopenias
ITP - Immune ThrombocytopeniaAIHA - Warm Autoimmune Hemolytic AnemiaAIHA - Cold Autoimmune Hemolytic Anemia
Ouro Medicines32 enrolled3 locationsNCT07083960
Recruiting
Phase 1
Umbilical Cord Blood Megakaryocyte Injection (XJ-MK-002) for Cancer Therapy-Induced Thrombocytopenia (CTIT)
CancerThrombocytopenia
Cancer Institute and Hospital, Chinese Academy of Medical Sciences16 enrolled1 locationNCT07110090
Recruiting
Phase 1
Inaticabtagene Autoleucel Injection in the Treatment of Refractory Systemic Lupus Erythematosus-related Immune Thrombocytopenia
Autoimmune Thrombocytopenia
Juventas Cell Therapy Ltd.12 enrolled1 locationNCT06826430
Recruiting
Phase 1Phase 2
A Clinical Study of NAD in the Treatment of Immune Thrombocytopenia
TreatmentImmune Thrombocytopenia
Institute of Hematology & Blood Diseases Hospital, China20 enrolled1 locationNCT06776510
Recruiting
Phase 1Phase 2
A Dose-escalation Study Followed by a Dose Optimal Study to Evaluate the Safety and Efficacy of CID-103 in Adults With Chronic Immune Thrombocytopenia
Chronic Immune Thrombocytopenia
CASI Pharmaceuticals, Inc.75 enrolled6 locationsNCT07017725
Recruiting
Phase 1Phase 2
A Phase 1/2 Study of ESG206 in Patients With Primary Immune Thrombocytopenia
Immune Thrombocytopenia (ITP)
Shanghai Escugen Biotechnology Co., Ltd84 enrolled1 locationNCT06853444
Recruiting
Phase 1
A Clinical Study of YTS109 Cell in R/R Systemic Lupus Erythematosus
Lupus Nephritis (LN)Immune Thrombocytopenia (ITP)
China Immunotech (Beijing) Biotechnology Co., Ltd.36 enrolled1 locationNCT06943937
Recruiting
Phase 1
UCMSC-Exo for Chemotherapy-induced Myelosuppression in Acute Myeloid Leukemia
Acute Myeloid LeukemiaThrombocytopeniaNeutropenia+3 more
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology9 enrolled1 locationNCT06245746
Completed
Phase 1
A Single-arm, Open-label, Single-dose, Phase I Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Recombinant Human Thrombopoietin for Injection (rhTPO) in Healthy Caucasian Volunteers
Thrombocytopenia
3SBIO AU PTY LTD22 enrolled1 locationACTRN12625000189426
Recruiting
Phase 1Phase 2
Efficacy and Safety of CAR-T Cells Therapy for Chronic or Refractory Primary Immune Thrombocytopenia (ITP)
ITP - Immune Thrombocytopenia
920th Hospital of Joint Logistics Support Force of People's Liberation Army of China10 enrolled1 locationNCT06352281
Terminated
Phase 1
A Phase I Open-Label, Single Dose, Dose Escalation Study of KB002, a Chimeric Monoclonal Antibody Which Binds to GM-CSF (Granulocyte Macrophage Colony Stimulating Factor), in Patients with Chronic Idiopathic Thrombocytopenia Purpura (ITP)
Idiopathic Thrombocytopenia Purpura (ITP)
KaloBios Pharmaceuticals Inc27 enrolled1 locationACTRN12606000459527