Phase 2 TME Clinical Trials
113 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 113 trials
Recruiting
Phase 2
Visugromab, Nivolumab and Lenvatinib Compared to Double Placebo and Lenvatinib in Unresectable or Metastatic Hepatocellular Carcinoma Post Anti-PD-(L)1 Failure
Unresectable or Metastatic Hepatocellular CarcinomaChild-Pugh A Hepatocellular CarcinomaFailure of First-Line Treatment That Included an Approved Anti PD-(L)1 Compound
CatalYm GmbH104 enrolled14 locationsNCT07219459
Recruiting
Phase 2
Zanzalintinib for the Treatment of Advanced Thyroid Cancer Before Surgery
Neoadjuvant TreatmentThyroid Cancer
M.D. Anderson Cancer Center45 enrolled3 locationsNCT06959511
Recruiting
Phase 2
Testing a Functional Precision Medicine Approach to Select Chemotherapy for Metastatic Colorectal Cancer (COSENSE-1)
Metastatic Colorectal CancerFirst-line TreatmentOrganoids+3 more
St. Olavs Hospital148 enrolled1 locationNCT06907342
Recruiting
Phase 2
ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response
Major Depressive Disorder (MDD)Depressive Disorder, Treatment-Resistant
ACADIA Pharmaceuticals Inc.153 enrolled23 locationsNCT07284667
Recruiting
Phase 2
Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression
DepressionDepressive DisorderMolecular Mechanisms of Pharmacological Action+10 more
National Institute of Mental Health (NIMH)50 enrolled1 locationNCT06511908
Recruiting
Phase 2
Efficacy and Safety Study of Romiplostim N01 for Cancer Treatment-induced Thrombocytopenia (CTIT) in the Treatment of Leukemia
Cancer Treatment-induced Thrombocytopenia (CTIT)
Anhui Provincial Hospital97 enrolled1 locationNCT06898983
Recruiting
Phase 1Phase 2
Cannabidiol Oil for Treatment-Resistant Major Depression
Major Depressive Disorder (MDD)Treatment Resistant Depression (TRD)
Universidade do Sul de Santa Catarina120 enrolled1 locationNCT07696871
Recruiting
Phase 2
An Open-Label Study to Evaluate the Safety, Tolerability and Pharmacodynamics of BPL-003 in Patients With Treatment Resistant Depression
Treatment Resistant Depression
Beckley Psytech Limited72 enrolled3 locationsNCT05660642
Recruiting
Phase 2Phase 3
Randomizing Two Radiotherapy Boost Options to Avoid Rectal Cancer Surgery
Rectal Cancer Stage IIIRectal Cancer PatientsOrgan Preservation+2 more
Sir Mortimer B. Davis - Jewish General Hospital131 enrolled4 locationsNCT03051464
Recruiting
Phase 1Phase 2
Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed).
ParagangliomaPheochromocytomaSolid Tumor Cancer+19 more
Fundación de investigación HM25 enrolled1 locationNCT06607692
Recruiting
Phase 2
RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses
Adjustment Disorder
Reunion Neuroscience Inc100 enrolled30 locationsNCT07002034
Recruiting
Phase 2
Imaging the Effects of Serotonin 2A Receptor Modulation on Synaptic Density in Treatment-resistant Depression (SYNVEST)
Treatment Resistant Depression
Centre for Addiction and Mental Health12 enrolled1 locationNCT06512220
Recruiting
Phase 2
The Bloom Infant Probiotic (BIP) Study
ImmunityInfant, NewbornAntibiotic Treatment+2 more
South Australian Health and Medical Research Institute360 enrolled2 locationsNCT07189390
Recruiting
Phase 1Phase 2
Venetoclax in Combination With Ivosidenib and Azacitidine for Newly Diagnosed IDH1-Mutated AML
TreatmentAMLIDH1 Mutation
Institute of Hematology & Blood Diseases Hospital, China23 enrolled1 locationNCT06611839
Recruiting
Phase 2
A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)
Treatment Resistant Depression
atai Therapeutics, Inc.142 enrolled48 locationsNCT06524830
Recruiting
Phase 2Phase 3
Total Neoadjuvant Therapy and Organ Preservation Versus Surgery for Rectal Cancer.
Radiotherapy Side EffectNeoadjuvant TherapyChemotherapy+8 more
National Cancer Center Affiliate of Vilnius University Hospital Santaros Klinikos400 enrolled1 locationNCT06758830
Recruiting
Phase 2
A Phase II Clinical Trial of the Safety and Efficacy of SAL056 at Different Doses and Dosing Regimens
postmenopausal women with osteoporosis
Shenzhen Salubris Pharmaceuticals Co., Ltd.200 enrolled1 locationNCT07579936
Recruiting
Phase 2
Safety and Efficacy of Umbilical Cord Blood Therapy for Cancer Therapy-Induced Thrombocytopenia (CTIT)
ThrombocytopeniaCancer Treatment-induced Thrombocytopenia
Zhejiang Cancer Hospital25 enrolled1 locationNCT07441720
Recruiting
Phase 2
Modulating Exercise Dosage to Improve Concussion Recovery
TreatmentDepression, AnxietyAerobic Exercise+2 more
University of Colorado, Denver216 enrolled3 locationsNCT05434130
Recruiting
Phase 2
Mindfulness Engaged Neurostimulation for Depression (MEND II)
DepressionDepressive DisorderDepressive Symptoms+2 more
University of California, San Diego120 enrolled1 locationNCT07512284