Transplant Clinical Trials in Philadelphia, Pennsylvania

31 recruitingPhiladelphia, Pennsylvania

Showing 120 of 31 trials

Recruiting
Phase 2

Tocilizumab in Lung Transplantation

Lung Transplant
National Institute of Allergy and Infectious Diseases (NIAID)350 enrolled21 locationsNCT06033196
Recruiting
Phase 2

Open Label Trial of Oral Letermovir for CMV Prophylaxis in Thoracic Transplant Recipients

Cytomegalovirus InfectionsTransplant-Related Disorder
University of Pennsylvania80 enrolled1 locationNCT06066957
Recruiting
Phase 2

Expanding Liver Transplant Immunosuppression Minimization Via Everolimus

Liver Transplant
National Institute of Allergy and Infectious Diseases (NIAID)340 enrolled8 locationsNCT06280950
Recruiting
Phase 3

A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and Chemotherapy

Epstein-Barr Virus+ Associated Post-transplant Lymphoproliferative Disease (EBV+ PTLD)Solid Organ Transplant ComplicationsLymphoproliferative Disorders+2 more
Pierre Fabre Medicament115 enrolled71 locationsNCT03394365
Recruiting
Phase 2

Advancing Transplantation Outcomes in Children

Kidney Transplant
National Institute of Allergy and Infectious Diseases (NIAID)200 enrolled20 locationsNCT06055608
Recruiting
Phase 1

CAR-T Cell Therapy for Desensitization in Kidney Transplantation

Kidney TransplantKidney FailureEnd Stage Renal Failure on Dialysis
National Institute of Allergy and Infectious Diseases (NIAID)20 enrolled3 locationsNCT06056102
Recruiting

Prospective Multicenter Research on Donor and Recipient Management Strategies to Improve Lung Transplant Outcomes

Lung Transplant; ComplicationsLung Transplant; Infection or InflammationLung Transplant Rejection+1 more
Duke University2,600 enrolled19 locationsNCT06399302
Recruiting
Phase 3

Double-blind, Randomized, Placebo-controlled, Multicenter Study to Evaluate the Efficacy and Safety of Ravulizumab Administered Intravenously in Adult Participants at High Risk of Delayed Graft Function After Kidney Transplantation

Kidney TransplantDelayed Graft FunctionDGF
Alexion Pharmaceuticals, Inc.450 enrolled130 locationsNCT06830798
Recruiting
Phase 2

Phase 2 Study of ALXN2030 in Patients With Antibody-Mediated Rejection After Kidney Transplantation

Kidney TransplantationAMRAntibody-mediated Rejection+1 more
Alexion Pharmaceuticals, Inc.45 enrolled55 locationsNCT06744647
Recruiting
Not Applicable

Massage Impact on Sleep in Pediatric Oncology

CancerAcute Myeloid LeukemiaChemotherapy Effect+3 more
Children's Hospital of Philadelphia70 enrolled2 locationsNCT06892158
Recruiting
Phase 2

Assessment of Biomarker-Guided CNI Substitution In Kidney Transplantation

Kidney Transplant
National Institute of Allergy and Infectious Diseases (NIAID)800 enrolled15 locationsNCT05917522
Recruiting
Phase 3

An Efficacy, Safety, and Tolerability Study of VX-880 in Participants With Type 1 Diabetes With a Kidney Transplant

Kidney TransplantType 1 Diabetes
Vertex Pharmaceuticals Incorporated10 enrolled7 locationsNCT06832410
Recruiting
Not Applicable

A Novel Digital Application (SHIFT) to Improve Outcomes for Hematopoietic Stem Cell Transplant Survivors

Sexual DysfunctionStem Cell Transplant ComplicationsBone Marrow Transplant Complications
Massachusetts General Hospital300 enrolled3 locationsNCT06541002
Recruiting
Phase 2

Orphan Indications for CD19 Redirected Autologous T Cells

Pediatric and Young Adult Patientswith Hypodiploid or t(17;19) B-ALLInfants With Very High Risk KMT2A B-ALLPatients With Central Nervous System Relapse Who Did Not Receive Cranial Radiation or Bone Marrow Transplantation
Stephan Grupp MD PhD133 enrolled1 locationNCT04276870
Recruiting

Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies

Solid TumorLeukemiaHematopoietic Cell Transplantation Recipient
Children's Oncology Group5,000 enrolled164 locationsNCT00736749
Recruiting

TRANSPIRE: Lung Injury in a Longitudinal Cohort of Pediatric HSCT Patients

Hematopoietic Stem Cell Transplant (HSCT)Thrombotic MicroangiopathiesDiffuse Alveolar Hemorrhage+2 more
Children's Hospital Medical Center, Cincinnati2,000 enrolled9 locationsNCT04098445
Recruiting

Identifying Genetic Characteristics That Increase Risk of Primary Graft Dysfunction Following Lung Transplantation

Primary Graft DysfunctionLung transplantation
University of Pennsylvania1,150 enrolled1 locationNCT00457847
Recruiting

Risk Factors That Increase the Chance of Developing Primary Graft Dysfunction After Lung Transplantation

Primary Graft DysfunctionLung transplantation
University of Pennsylvania1,150 enrolled1 locationNCT00552357
Recruiting
Not Applicable

Technology Enabled Strategies to Promote Treatment Adherence in Liver Transplant

CirrhosisLiver Transplant; ComplicationsEnd Stage Liver Disease+1 more
University of Pennsylvania360 enrolled3 locationsNCT05260268
Recruiting

US National OCS Liver Perfusion (OLP) Registry

Liver Transplant
TransMedics100,000 enrolled22 locationsNCT05940857