Phase 2 Transplant Clinical Trials
124 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 124 trials
Recruiting
Phase 2
The Efficacy, Mechanism & Safety of Sodium Glucose Co-Transporter-2 Inhibitor & Glucagon-Like Peptide 1 Receptor Agonist Combination Therapy in Kidney Transplant Recipients
Kidney Transplant Recipients
University Health Network, Toronto20 enrolled1 locationNCT05938712
Recruiting
Phase 2
Nonmyeloablative Stem Cell Transplant in Children With Sickle Cell Disease and a Major ABO-Incompatible Matched Sibling Donor
Sickle Cell DiseaseStem Cell Transplant ComplicationsPure Red Cell Aplasia+1 more
University of Calgary12 enrolled1 locationNCT03214354
Recruiting
Phase 2
Ivosidenib as Post-HSCT Maintenance for AML
Acute Myeloid Leukemia (AML)IDH1 MutationHematopoietic Stem Cell Transplant (HSCT)
Massachusetts General Hospital75 enrolled4 locationsNCT06707493
Recruiting
Phase 1Phase 2
The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell Transplantation
Hematopoietic Stem Cell TransplantationPeripheral Blood Stem Cell Transplantation
National Cancer Institute (NCI)260 enrolled2 locationsNCT05436418
Recruiting
Phase 2
PUL-042 Treatment in Patients With Parainfluenza Virus (PIV), Human Metapneumovirus (hMPV) or Respiratory Syncytial Virus (RSV)
Hematologic MalignanciesHematopoietic Stem Cell Transplant (HSCT)
Pulmotect, Inc.100 enrolled11 locationsNCT06665100
Recruiting
Phase 2
A Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Subjects With VEXAS (Vacuoles, E1 Enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Hematopoietic Stem Cell TransplantationImmunodeficiency
National Cancer Institute (NCI)54 enrolled1 locationNCT05027945
Recruiting
Phase 2Phase 3
A Study to Investigate the Efficacy and Safety of Frexalimab Versus Tacrolimus in Adults Undergoing Kidney Transplantation
Kidney Transplant Rejection
Sanofi526 enrolled10 locationsNCT07412470
Recruiting
Phase 2
REgulatory T Cell Therapy to Achieve Immunosuppression REduction
Kidney Transplantation
Singulera Therapeutics Inc.34 enrolled7 locationsNCT06552169
Recruiting
Phase 2
Ruxolitinib and Chidamide Intensified Bu/CY Conditioning Regimen
Peripheral Blood Stem Cell Transplantation
Chinese PLA General Hospital50 enrolled1 locationNCT05088226
Recruiting
Phase 2
Imlifidase Prior to Kidney Transplant in Highly Sensitised Children
Kidney Transplantation in Highly Sensitized Patients
Hansa Biopharma AB10 enrolled5 locationsNCT05753930
Recruiting
Phase 2
Study on the Efficacy and Safety of the TmBU Conditioning Regimen in High-risk or Relapsed/Refractory Acute Leukemia
Acute Lymphoblastic LeukemiaAcute Myeloid LeukemiaTransplantation, Stem Cell+1 more
The First Affiliated Hospital of Soochow University48 enrolled1 locationNCT06816134
Recruiting
Phase 2
ExCrossV Multi Site Trial for Vascularized High Risk Keratoplasty
Corneal Transplant Failure
Massachusetts Eye and Ear Infirmary96 enrolled12 locationsNCT06753916
Recruiting
Phase 2
Belumosudil to Block Chronic Lung Allograft Dysfunction (CLAD) in High Risk Lung Transplant Recipients
Lung Transplant
National Institute of Allergy and Infectious Diseases (NIAID)234 enrolled12 locationsNCT06476132
Recruiting
Phase 2
High vs.Standard Dose Influenza Vaccine in Pediatric Solid Organ Transplant (SOT) Recipients
InfluenzaTransplantation InfectionImmunization; Infection
National Institute of Allergy and Infectious Diseases (NIAID)312 enrolled8 locationsNCT05947071
Recruiting
Phase 2
GM-CSF With Post-Transplant Cyclophosphamide
Transplant-Related Hematologic Malignancy
Northside Hospital, Inc.38 enrolled1 locationNCT04237623
Recruiting
Phase 2
Early Use of Tacrolimus in HLA-Mismatched Haploidentical Allogeneic Hematopoietic Transplantation With Post-Transplant Cyclophosphamide
Hematologic Disease and DisordersHematopoietic Cell Transplant
Northside Hospital, Inc.20 enrolled1 locationNCT06828796
Recruiting
Phase 2
Amimestrocel Injection for Preventing Severe Oral Mucositis in HSCT Patients
Oral MucositisHematopoietic Stem Cell TransplantationStomatitis+1 more
The First Affiliated Hospital of Soochow University22 enrolled1 locationNCT07400328
Recruiting
Phase 2
Tafasitamab and Rituximab for Front-Line Treatment of Post-Transplant Lymphoproliferative Disorder
Monomorphic B-Cell Post-Transplant Lymphoproliferative DisorderPolymorphic Post-Transplant Lymphoproliferative Disorder
Timothy Voorhees28 enrolled4 locationsNCT05786040
Recruiting
Phase 2
The EFfect of FinErenone in Kidney TransplantiOn Recipients: The EFFEKTOR Study
Kidney Transplant; Complications
University of North Carolina, Chapel Hill100 enrolled1 locationNCT06059664
Recruiting
Phase 2Phase 3
CIRTEN-Simultaneous Pancreas-Kidney Transplant Recipients
Kidney Pancreas Transplantation
University of Wisconsin, Madison20 enrolled1 locationNCT03769298