Phase 2 Tumors Clinical Trials
314 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 314 trials
Recruiting
Phase 2
A Study to Evaluate the Safety and Pharmacokinetics of Eflapegrastim in Pediatric Participants With Solid Tumors or Lymphomas and Treated With Myelosuppressive Chemotherapy
Solid TumorsLymphoma
Spectrum Pharmaceuticals, Inc40 enrolled5 locationsNCT04570423
Recruiting
Phase 1Phase 2
Personalized Neoantigen Peptide Vaccines for Solid Tumors
Solid TumorsAdvanced CancerRecurrent Cancer+2 more
Seqker Biosciences, Inc.10 enrolled1 locationNCT07002203
Recruiting
Phase 1Phase 2
An Open, Single-center Clinical Study of Surufatinib Combined With Temozolomide and S-1 in the First-line Treatment of Advanced Neuroendocrine Tumors
Neuroendocrine Tumors
Cancer Institute and Hospital, Chinese Academy of Medical Sciences40 enrolled1 locationNCT06038461
Recruiting
Phase 2
A UGT1A1 Genotype-Directed Study of Belinostat Pharmacokinetics and Toxicity
Neuroendocrine CarcinomaCarcinoma, NeuroendocrineTumor, Neuroendocrine+2 more
National Cancer Institute (NCI)60 enrolled1 locationNCT06406465
Recruiting
Phase 1Phase 2
A Study of SHR-4610 Injection in Patients With Advanced Solid Tumors
Solid Tumors
Shanghai Shengdi Pharmaceutical Co., Ltd258 enrolled1 locationNCT07231211
Recruiting
Phase 1Phase 2
A Study to Evaluate Claudin 18.2-Directed ADC LCB02A in Advanced Solid Tumors
Advanced Solid Tumors
LigaChem Biosciences, Inc.191 enrolled8 locationsNCT07460375
Recruiting
Phase 2
A Rollover Study Evaluating Sotorasib With or Without Panitumumab in Participants With KRAS p.G12C Mutation
Advanced Solid Tumors
Amgen14 enrolled11 locationsNCT07172919
Recruiting
Phase 1Phase 2
Safety and Efficacy of Ponatinib for Treatment of Pediatric Recurrent or Refractory Leukemias, Lymphomas or Solid Tumors
Solid TumorsAcute Lymphoblastic LeukemiaAcute Myeloid Leukemia+6 more
Incyte Biosciences International Sàrl70 enrolled23 locationsNCT03934372
Recruiting
Phase 1Phase 2
A Study of ZL-1310 in Participants With Selected Solid Tumors
Solid Tumors
Zai Lab (Shanghai) Co., Ltd.166 enrolled23 locationsNCT06885281
Recruiting
Phase 1Phase 2
PEEL-224, Vincristine and Temozolomide in Pediatric Solid Tumors
Refractory NeuroblastomaRefractory RhabdomyosarcomaRefractory Solid Tumors+3 more
Theodore Laetsch59 enrolled7 locationsNCT06721689
Recruiting
Phase 1Phase 2
CR-001 in Adult Participants With Locally Advanced or Metastatic Solid Tumors
Locally Advanced/Metastatic Solid Tumors
Crescent Biopharma, Inc.290 enrolled25 locationsNCT07335497
Recruiting
Phase 2Phase 3
PRO-BOOST-LC: Whole-Gland Boost Strategies Versus SBRT Monotherapy in PSMA-Staged Localized and Locally Advanced Prostate Cancer
Prostate Cancer (Adenocarcinoma)Stereotactic Body Radiation Therapy (SBRT)Localized Prostate Cancer+2 more
Affidea Nu-med Center of Oncological DIagnostics and Therapy1,000 enrolled1 locationNCT07426055
Recruiting
Phase 2Phase 3
PRO-BOOST-N: Prostate-First Versus Combined Prostate and Nodal Dose Escalation in PSMA PET-Staged Node-Positive Prostate Cancer
Prostate CancerBrachytherapyStereotactic Body Radiation Therapy (SBRT)+2 more
Affidea Nu-med Center of Oncological DIagnostics and Therapy600 enrolled1 locationNCT07426094
Recruiting
Phase 1Phase 2
Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma
Brain CancerGBMGlioma+12 more
National Institute of Neurological Disorders and Stroke (NINDS)40 enrolled1 locationNCT07416188
Recruiting
Phase 1Phase 2
A Study of TAK-188 in Adults With Advanced or Spreading Solid Tumors
Advanced or Metastatic Solid Tumors
Takeda223 enrolled15 locationsNCT07205718
Recruiting
Phase 2
Phase II Study of Becotatug Vedotin Plus Pucotenlimab for Advanced Refractory Solid Tumors With EGFR-Positive
Advanced Refractory Solid TumorsEGFR Gene Overexpression
Tianjin Medical University Second Hospital32 enrolled1 locationNCT07712029
Recruiting
Phase 1Phase 2
Study of RAS(ON) Inhibitors in Combination With Ivonescimab in Patients With Solid Tumors
Non-small Cell Lung Cancer (NSCLC)Advanced Solid TumorsNSCLC+3 more
Revolution Medicines, Inc.370 enrolled6 locationsNCT07397338
Recruiting
Phase 1Phase 2
Trial of Single Protein Encapsulated Doxorubicin, SPEDOX-6 in Advanced Malignancies
Triple-Negative Breast CancerOvarian CancerCervical Cancer+3 more
University of California, Irvine67 enrolled1 locationNCT07064018
Recruiting
Phase 2
A Study to Assess Adverse Events and Change in Disease Activity in Participants 12 Years of Age or Older With Locally Advanced or Metastatic Solid Tumors That Harbor MET Amplification Receiving Intravenously Infused Telisotuzumab Adizutecan
Solid Tumors Harboring MET Amplification
AbbVie100 enrolled35 locationsNCT07196644
Recruiting
Phase 1Phase 2
Rollover Study for Participants Who Have Been Treated With and Are Continuing to Benefit From Opnurasib as a Single Agent or in Combination With Other Study Treatments
Locally Advanced or Metastatic KRAS G12C-mutated Non-small Cell Lung CancerAdvanced Solid Tumors Harboring the KRAS G12C Mutation
Novartis Pharmaceuticals40 enrolled7 locationsNCT07468071