Phase 3 Tumors Clinical Trials
20 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 20 trials
Recruiting
Phase 3
A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
Solid Tumors
Incyte Corporation588 enrolled213 locationsNCT07522073
Recruiting
Phase 3
Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)
Solid TumorsHematologic Malignancies
Merck Sharp & Dohme LLC3,500 enrolled781 locationsNCT03486873
Recruiting
Phase 3
Efficacy and Safety of Radiotherapy Compared to Everolimus in Somatostatin Receptor Positive Neuroendocrine Tumors of the Lung and Thymus.
Neuroendocrine TumorsLung Neuroendocrine NeoplasmThymus Neoplasms
Grupo Espanol de Tumores Neuroendocrinos170 enrolled27 locationsNCT05918302
Recruiting
Phase 2Phase 3
Sirolimus for Injection (Albumin Bound) Combined With Octreotide Long-acting Injection in Patients With Metastatic Gastroenteropancreatic Neuroendocrine Tumors
Gastroenteropancreatic Neuroendocrine Tumors
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.298 enrolled1 locationNCT07165886
Recruiting
Phase 2Phase 3
Application of Al18F-octreotide PET/CT in Tumors With Positive SSTR Expression
SSTR Positive Tumors
Cancer Institute and Hospital, Chinese Academy of Medical Sciences400 enrolled1 locationNCT05749289
Recruiting
Phase 3
Study of RYZ101 Compared With SOC in Pts w Inoperable SSTR+ Well-differentiated GEP-NET That Has Progressed Following 177Lu-SSA Therapy
Neuroendocrine TumorsGep NetCarcinoid Tumor+4 more
RayzeBio, Inc.338 enrolled54 locationsNCT05477576
Recruiting
Phase 2Phase 3
PRO-BOOST-N: Prostate-First Versus Combined Prostate and Nodal Dose Escalation in PSMA PET-Staged Node-Positive Prostate Cancer
Prostate CancerBrachytherapyStereotactic Body Radiation Therapy (SBRT)+2 more
Affidea Nu-med Center of Oncological DIagnostics and Therapy1,600 enrolled1 locationNCT07426094
Recruiting
Phase 2Phase 3
PRO-BOOST-LC: Whole-Gland Boost Strategies Versus SBRT Monotherapy in PSMA-Staged Localized and Locally Advanced Prostate Cancer
Prostate Cancer (Adenocarcinoma)Stereotactic Body Radiation Therapy (SBRT)Localized Prostate Cancer+2 more
Affidea Nu-med Center of Oncological DIagnostics and Therapy1,200 enrolled1 locationNCT07426055
Recruiting
Phase 2Phase 3
Pan-tumor Neoadjuvant Basket Study of Immune Check-point Inhibition and Novel Immuno-oncology Combinations
Resectable MMR-deficient Solid TumorsResectable MMR-proficient Solid Tumors
The Netherlands Cancer Institute133 enrolled1 locationNCT06279130
Recruiting
Phase 3
90Yttrium Colloid for the Treatment of Cystic Sellar/Parasellar Tumors
Cystic Tumors of the Sellar/Parasellar Region
David Clarke40 enrolled1 locationNCT02081768
Recruiting
Phase 3
Short Versus Long-term Levetiracetam in Brain Tumors
SeizuresBrain TumorsAntiepileptics+1 more
Tata Memorial Centre604 enrolled2 locationsNCT06442748
Recruiting
Phase 3
18F-DOPA II - PET Imaging Optimization
Neuroendocrine TumorsBrain TumorNeuroblastoma+3 more
University of Alberta800 enrolled1 locationNCT04706910
Recruiting
Phase 3
Systemic Targeted Adaptive RadioTherapy of NeuroEndocrine Tumors.
Neuroendocrine Tumors
Lund University Hospital300 enrolled4 locationsNCT05387603
Recruiting
Phase 3
Randomized Interval Assessment Trial of Lu177-Dotatate in Slowly Progressive G1-2 Advanced Midgut Neuroendocrine Tumors
Grade1-2 Advanced Midgut Neuroendocrine Tumors (NETs)
Grupo Espanol de Tumores Neuroendocrinos166 enrolled21 locationsNCT06878664
Recruiting
Phase 2Phase 3
Absorbed Tumor Dose in Peptide Receptor Radionuclide Therapy with Long-acting Somatostatin Analogues - ATSA Trial
Neuroendocrine NeoplasmNeuroendocrine TumorsNeuroendocrine Tumor Grade 1+1 more
The Netherlands Cancer Institute39 enrolled1 locationNCT06855095
Recruiting
Phase 3
68Ga-DOTA-TATE PET/CT Imaging in NETs
Neuroendocrine Tumors
Centre de recherche du Centre hospitalier universitaire de Sherbrooke5,000 enrolled2 locationsNCT04847505
Withdrawn
Phase 3
Radiation Therapy With Concomitant and Adjuvant Temozolomide Versus Radiation Therapy With Adjuvant PCV Chemotherapy in Patients With Anaplastic Glioma or Low Grade Glioma
Brain and Central Nervous System Tumors
Alliance for Clinical Trials in Oncology360 enrolled66 locationsACTRN12620000402943
Active
Phase 3
Radiation Therapy or Temozolomide in Treating Patients With Gliomas
Brain and Central Nervous System Tumors
European Organisation for Research and Tretment of Cancer (EORTC)699 enrolled34 locationsACTRN12607000427471
Terminated
Phase 3
QUARTZ - Quality of Life After Radiotherapy and Steroids
Lung CancerBrain and Central Nervous System Tumors
Tanya Holt1,000 enrolled1 locationACTRN12607000264482
Completed
Phase 3
Advanced GIST
Patients with unresectable or metastatic gastrointestional stromal tumors (GIST) expressing the kit receptor tyrosine kinase (CD117)
Novartis Australia946 enrolled19 locationsACTRN12605000138684