Phase 1 Type 1 Diabetes Mellitus Clinical Trials

8 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 18 of 8 trials

Recruiting
Phase 1

A Study of GNTI-122 in Adults Recently Diagnosed With T1D

Type 1 Diabetes MellitusType 1 Diabetes (T1D)
GentiBio, Inc16 enrolled10 locationsNCT06919354
Recruiting
Phase 1Phase 2

CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)

Type 1 DiabetesType 1 Diabetes MellitusType 1 Diabetes Mellitis+7 more
COUR Pharmaceutical Development Company, Inc.72 enrolled31 locationsNCT06783309
Recruiting
Phase 1Phase 2

Safety, Tolerability, and Efficacy of Immunomodulation With A Monoclonal Antibody Against CD40L in Combination With Transplanted Islet Cells in Adults With Brittle Type 1 Diabetes Mellitus (T1D)

Type 1 Diabetes Mellitus
University of Chicago70 enrolled1 locationNCT06305286
Recruiting
Phase 1Phase 2

A Study to Investigate Safety and Effectiveness of Porcine Pancreatic Cells (OPF-310) in Patients With Type 1 Diabetes Mellitus

Metabolic DiseaseDiabetes Mellitus, Type 1Type 1 Diabetes+14 more
Otsuka Pharmaceutical Factory, Inc.13 enrolled1 locationNCT06575426
Recruiting
Phase 1

A Study of LY3938577 in Healthy Participants and Participants With Type 1 Diabetes Mellitus (T1DM)

HealthyType 1 Diabetes Mellitus
Eli Lilly and Company118 enrolled1 locationNCT06280703
Recruiting
Phase 1

Subcutaneous Pharmacokinetic Evaluation of Monomeric Insulin and Lyumjev in Adults With Type 1 Diabetes

Diabetes Mellitus, Type 1Type 1 Diabetes Mellitus
Stanford University20 enrolled1 locationNCT07090824
Recruiting
Phase 1

Efficacy of Adipose Tissue Derived Stem Cells for the Treatment of Diabetic Foot Ulcers

Diabetes MellitusDiabetic Foot UlcerDiabetic Foot+8 more
University of the Punjab28 enrolled1 locationNCT05610865
Recruiting
Phase 1

Immunotherapy with Autologous Tregs in T1DM

Type 1 Diabetes Mellitus
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School20 enrolled1 locationNCT06708780