Phase 2 Ulcerative Colitis Clinical Trials
52 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 52 trials
Recruiting
Phase 2
A Study to Evaluate Efficacy and Safety of MK-8690 in Participants With Moderately to Severely Active Ulcerative Colitis (MK-8690-002)
Ulcerative ColitisColitis Ulcerative
Merck Sharp & Dohme LLC100 enrolled9 locationsNCT07463183
Recruiting
Phase 1Phase 2
Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis
Ulcerative Colitis (UC)
Xencor, Inc.270 enrolled66 locationsNCT06619990
Recruiting
Phase 2Phase 3
Efficacy and Safety of Oral Controlled-Ileocolonic-Release Nicotinamide (CICR-NAM) in Patients With Mild to Moderately Active Ulcerative Colitis
Ulcerative Colitis, Unspecified
University Hospital Schleswig-Holstein459 enrolled26 locationsNCT06488625
Recruiting
Phase 2
A Study to Evaluate Etrasimod Treatment in Adolescents With Ulcerative Colitis
Ulcerative Colitis
Pfizer36 enrolled46 locationsNCT05287126
Recruiting
Phase 2
A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis
ColitisInflammatory Bowel DiseasesUlcerative Colitis+1 more
Spyre Therapeutics, Inc.645 enrolled223 locationsNCT07012395
Recruiting
Phase 1Phase 2
A Study to Evaluate the Activity, and Safety of Vixarelimab in Participants With Moderate to Severe Active Ulcerative Colitis
Moderate to Severe Ulcerative Colitis
Genentech, Inc.24 enrolled1 locationNCT06693908
Recruiting
Phase 2
LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:
Ulcerative Colitis
Eli Lilly and Company252 enrolled150 locationsNCT07186101
Recruiting
Phase 2
LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis
Ulcerative Colitis (UC)Ulcerative Colitis, Active ModerateUlcerative Colitis, Active Severe
Eli Lilly and Company1,431 enrolled253 locationsNCT07415044
Recruiting
Phase 2
The Use of Butyrate Therapy in Pediatric Ulcerative Colitis
Ulcerative Colitis
Children's Hospital Los Angeles10 enrolled1 locationNCT05218850
Recruiting
Phase 2
A Study to Test Whether BI 3032950 Helps People With Ulcerative Colitis
Ulcerative Colitis
Boehringer Ingelheim80 enrolled41 locationsNCT06636656
Recruiting
Phase 2
A Phase 2 Clinical Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of HRS-7085 Tablets in Patients With Inflammatory Bowel Disease
Adult Patients With Moderately to Severely Active Ulcerative Colitis
Shandong Suncadia Medicine Co., Ltd.48 enrolled1 locationNCT07229950
Recruiting
Phase 2
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics (PK) of RO7837195 in Participants With Moderately to Severely Active Ulcerative Colitis (UC)
Ulcerative Colitis
Genentech, Inc.224 enrolled90 locationsNCT06979336
Recruiting
Phase 2
Selenium Supplementation in Moderate-Severely Active Ulcerative Colitis Patients Treated With Advanced Therapies
Ulcerative Colitis (UC)
Northwestern University180 enrolled1 locationNCT07427017
Recruiting
Phase 2
A Continuation Study of TAK-279 in Adults With Ulcerative Colitis (UC) and Crohn's Disease (CD)
Crohn's DiseaseUlcerative Colitis
Takeda192 enrolled16 locationsNCT06764615
Recruiting
Phase 2
A Phase 2 Study to Evaluate the Efficacy, Safety and Pharmacokinetics of SHR-1139 in Patients With Moderate-to-severe Active Ulcerative Colitis
Adult Patients With Moderately to Severely Active Ulcerative Colitis
Guangdong Hengrui Pharmaceutical Co., Ltd20 enrolled1 locationNCT07232576
Recruiting
Phase 2
LFMT vs Placebo in New Biologic Start for Ulcerative Colitis
Ulcerative Colitis
University of Alberta40 enrolled1 locationNCT05327790
Recruiting
Phase 2
A Study to Investigate the Efficacy and Safety of SAR442970 in Adult Participants With Ulcerative Colitis
Ulcerative Colitis
Sanofi99 enrolled67 locationsNCT06975722
Recruiting
Phase 2
A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis
Ulcerative ColitisUlcerative Colitis Chronic
Eli Lilly and Company140 enrolled207 locationsNCT06598943
Recruiting
Phase 2
Patient Preference for Subcutaneous vs. Intravenous Immune Therapy
Esophageal CancerCervical CancerHepatocellular Carcinoma+9 more
Diwakar Davar880 enrolled1 locationNCT07223424
Recruiting
Phase 1Phase 2
A Study of MB-001 in Moderately to Severely Active Ulcerative Colitis
Ulcerative Colitis (UC)
Mage Biologics100 enrolled1 locationNCT07374471