Phase 1 Unresectable Locally Advanced Clinical Trials

7 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 17 of 7 trials

Recruiting
Phase 1Phase 2

Dual-Target CAR-NK Cells Targeting Mesothelin (MSLN) and MUC1 in Advanced Pancreatic Ductal Adenocarcinoma

Pancreatic Ductal Adenocarcinoma (PDAC)Metastatic DiseaseUnresectable Locally Advanced
Beijing Biotech42 enrolled1 locationNCT07627711
Recruiting
Phase 1Phase 2

Dual-Targeting CAR-NK Cells Targeting Mesothelin (MSLN) and MUC1 in Advanced Pancreatic Ductal Adenocarcinoma

Pancreatic Ductal Adenocarcinoma (PDAC)Unresectable Locally Advanced or Metastatic Disease
Beijing Biotech42 enrolled1 locationNCT07480928
Recruiting
Phase 1Phase 2

IBI3014 in Participants With Unresectable Locally Advanced or Metastatic Solid Tumors

Unresectable Locally Advanced or Metastatic Solid Tumors
Innovent Biologics (Suzhou) Co. Ltd.250 enrolled3 locationsNCT06974812
Recruiting
Phase 1Phase 2

Phase I/II Clinical Study of JMT108 Injection for the Treatment of Advanced Malignant Melanoma

Unresectable Locally Advanced or Metastatic Melanoma
Shanghai JMT-Bio Inc.188 enrolled1 locationNCT07280832
Recruiting
Phase 1Phase 2

First-in-human Trial of STC-1010, an Immunotherapy, in Patients With Unresectable Locally Advanced or Metastatic Colorectal Cancer

Unresectable Metastatic Colorectal CancerUnresectable Locally Advanced Colorectal Cancer
Brenus Pharma90 enrolled9 locationsNCT06934538
Recruiting
Phase 1Phase 2

TSN222 in Subjects With Advanced Solid Tumors or Lymphomas

Has a Pathologically Documented Unresectable Locally Advanced or Metastatic Solid Tumor or Lymphoma
Tyligand Bioscience (Shanghai) Limited162 enrolled1 locationNCT05842785
Recruiting
Phase 1Phase 2

Immunotherapy in Combination With Chemoradiotherapy in Unresectable Locally Advanced Esophageal Cancer

Esophageal Squamous Cell CarcinomaUnresectable Locally Advanced Esophageal Cancer
Shanghai Chest Hospital50 enrolled1 locationNCT06173986