Phase 1 Vaccine Clinical Trials
10 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–10 of 10 trials
Recruiting
Phase 1
Clinical Trial of IL - 22BP Safety, Tolerability, and Antitumor Activity in Refractory Solid Tumors.
Refractory Malignant Solid TumorsmRNA VaccineInterleukin
West China Hospital6 enrolled2 locationsNCT07040943
Recruiting
Phase 1Phase 2
Study to Evaluate the Safety and Immunogenicity of a Lyophilized Herpes Zoster Virus mRNA Vaccine
Herpes ZostermRNA Vaccine
Sinovac Biotech Co., Ltd519 enrolled1 locationNCT07400003
Recruiting
Phase 1
A Clinical Trial Evaluating IL-22BP/LNP Compound in Refractory Malignant Solid Tumors for Safety, Tolerability and Activity
Refractory Malignant Solid TumorsmRNA VaccineInterleukin
Xingchen Peng6 enrolled1 locationNCT07100210
Recruiting
Phase 1Phase 2
Personalized Neoantigen Peptide Vaccines for Solid Tumors
Solid TumorsAdvanced CancerRecurrent Cancer+2 more
Seqker Biosciences, Inc.10 enrolled2 locationsNCT07002203
Recruiting
Phase 1
Thymalfasin (Thymosin Alpha 1; Ta1) as an Enhancer of Vaccine Response Among Older Adults Receiving Booster Doses of COVID-19 Vaccine
Vaccine Response
The Methodist Hospital Research Institute75 enrolled1 locationNCT06821100
Recruiting
Phase 1
Safety and Immunogenicity of a Self-Amplifying RNA Vaccine Against Crimean-Congo Hemorrhagic Fever
VaccineCrimean-Congo Hemorrhagic Fever
HDT Bio48 enrolled1 locationNCT06799013
Recruiting
Phase 1
Personalized mRNA Cancer Vaccine for Gastrointestinal Solid Tumor Treatment
Gastrointestinal TumorsPersonalized Neoantigen Vaccine in Combination With Anti-PD-1 Inhibitors in Standard Therapy-Failed and Adjuvant Therapy
Ruijin Hospital40 enrolled1 locationNCT07067385
Recruiting
Phase 1
An Open-label, Dose-finding, Phase I Study to Evaluate the Safety and Immunogenicity of a Bivalent Klebsiella Pneumoniae Vaccine (CHO-V08) in Healthy Adults
VaccineKlebsiella Pneumoniae Infection
Cho Pharma Inc.40 enrolled1 locationNCT07016152
Recruiting
Phase 1
a Polyphenol Whole Tumor Cell Vaccine in Patients With Advanced Malignant Solid Tumors
Advanced Solid TumorCancer VaccinePolyphenols
Xingchen Peng9 enrolled1 locationNCT06878612
Completed
Phase 1
Clinical trial investigating if anti-malaria treatment DSM265 causes an allergic reaction.
Tolerability of Anti-Malaria Vaccine
Medicines for Malaria Venture (MMV) - Non Profit Product Development Partnership11 enrolled1 locationACTRN12617000711314