Vaccine Clinical Trials

1 recruiting

Frequently Asked Questions

Common questions about Vaccine clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 110 of 10 trials

Recruiting

Serologic Response to Pneumococcal Vaccination Among Esophageal Cancer Patients With High Grade Lymphopenia After Chemoradiation

Esophageal CancerChemoradiationPneumococcal Vaccine+1 more
M.D. Anderson Cancer Center80 enrolled1 locationNCT06181656
Recruiting
Phase 2

Phase II Trial of Neoadjuvant Chemotherapy (NAC) Alone or in Combination With Immunotherapy Vaccine PRGN-2009 in Subjects With Newly Diagnosed HPV-Associated Oropharyngeal (Head and Neck) Cancer

Squamous Cell Carcinoma of the Head and NeckDrug TherapyOropharynx+2 more
National Cancer Institute (NCI)70 enrolled1 locationNCT06223568
Recruiting
Phase 4

Clinical Trial Assessing the Immunogenicity of an Anti-pneumococcal Vaccination Strategy (PCV13+PPV23 Versus PREVENAR20) in Adult Patients Treated for a Lymphoma

Lymphoma, Non-HodgkinStreptococcus PneumoniaeVaccine
Poitiers University Hospital160 enrolled7 locationsNCT04460235
Recruiting
Not Applicable

Advancing HPV Vaccination Among HIV Positive Adults: The CHAMPS Study

Human Papilloma VirusHuman Papilloma Virus Vaccine
Emory University365 enrolled4 locationsNCT05065840
Recruiting
Phase 4

Immunogenicity of Gardasil-9 HPV Vaccine in People Living With HIV

Papillomavirus InfectionHuman Immunodeficiency VirusCervical Intraepithelial Neoplasia+4 more
Louisiana State University Health Sciences Center in New Orleans250 enrolled1 locationNCT05266898
Recruiting
Not Applicable

Integration to Improve Adolescent Health and HPV Vaccination in Laos

HealthyAdolescentsIntegrated, Community-Health Systems+5 more
Health Poverty Action700 enrolled1 locationNCT06650956
Recruiting

Multiple Human Papillomavirus Infections in the Development of CIN

HPVCIN - Cervical Intraepithelial NeoplasiaHPV Vaccines
Fondazione IRCCS Policlinico San Matteo di Pavia152 enrolled1 locationNCT06862102
Recruiting
Phase 2

Neoantigen Vaccines in Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma (ESCC)Neoantigen-loaded Dendritic Cell VaccineImmune Checkpoint Inhibitors (ICIs)
Sichuan University165 enrolled1 locationNCT06675201
Recruiting
Not Applicable

B. Infantis Supplementation to Improve Immunity in Infants Exposed to HIV

Infant DevelopmentHIVMicrobial Colonization+1 more
University of Cape Town200 enrolled1 locationNCT05923333
Recruiting
Phase 3

Multicenter Clinical Trial on the Effectiveness and Safety of Instillation of BCG and Alternative BCG Protocols for Intermediate and High-risk Non-muscle Invasive Bladder Cancer

Urinary Bladder NeoplasmsTreatment OutcomeImmunotherapy, Active+3 more
Fujian Medical University Union Hospital76 enrolled1 locationNCT06441110