Vaccine Clinical Trials

87 recruitingLast updated: June 18, 2026

There are 87 actively recruiting vaccine clinical trials across 36 countries. Studies span Not Applicable, Phase 4, Phase 1, Phase 3, Phase 2, Early Phase 1. Top locations include Taipei, Taiwan, Atlanta, Georgia, United States, Houston, Texas, United States. Updated daily from ClinicalTrials.gov.


Vaccine Trials at a Glance

87 actively recruiting trials for vaccine are listed on ClinicalTrialsFinder across 6 cities in 36 countries. The largest study group is Not Applicable with 23 trials, with the heaviest enrollment activity in Taipei, Atlanta, and Houston. Lead sponsors running vaccine studies include Fondazione IRCCS Policlinico San Matteo di Pavia, National Taiwan University Hospital, and Canadian Immunization Research Network.

Treatments under study

About Vaccine Clinical Trials

Looking for clinical trials for Vaccine? There are currently 7 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Vaccine trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Vaccine clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 87 trials

Recruiting
Phase 2

Phase II Trial of Neoadjuvant Chemotherapy (NAC) Alone or in Combination With Immunotherapy Vaccine PRGN-2009 in Subjects With Newly Diagnosed HPV-Associated Oropharyngeal (Head and Neck) Cancer

Squamous Cell Carcinoma of the Head and NeckDrug TherapyOropharynx+2 more
National Cancer Institute (NCI)70 enrolled1 locationNCT06223568
Recruiting

Reduced Vaccine Response to HZ/su in SLE

Systemic Lupus ErythematosusZosterVaccine Reaction
Seoul National University Hospital80 enrolled1 locationNCT07636044
Recruiting

How Gut Health Affects Immune Responses to the Oral Rotavirus Vaccine in Adults in Zambia

TranscriptomicsFeasibility StudyVaccine Immune Response+1 more
Centre for Infectious Disease Research in Zambia43 enrolled1 locationNCT07626606
Recruiting
Phase 4

Clinical Trial Assessing the Immunogenicity of an Anti-pneumococcal Vaccination Strategy (PCV13+PPV23 Versus PREVENAR20) in Adult Patients Treated for a Lymphoma

Lymphoma, Non-HodgkinStreptococcus PneumoniaeVaccine
Poitiers University Hospital160 enrolled7 locationsNCT04460235
Recruiting

Vaccine Confidence Study Among Historically Marginalized Racial and Ethnic Groups

Vaccine RefusalVaccine Hesitancy
Boston Medical Center80 enrolled1 locationNCT06639386
Recruiting

Serologic Response to Pneumococcal Vaccination Among Esophageal Cancer Patients With High Grade Lymphopenia After Chemoradiation

Esophageal CancerChemoradiationPneumococcal Vaccine+1 more
M.D. Anderson Cancer Center80 enrolled1 locationNCT06181656
Recruiting
Not Applicable

The STOP-HPV Scale Up Study

Human Papilloma Virus Vaccine
University of California, Los Angeles100,000 enrolled1 locationNCT06831383
Recruiting
Not Applicable

Playing Game to Learn About Children's Vaccine Project

vaccine preventable diseasesHPV
Michigan State University180 enrolled1 locationNCT05984849
Recruiting
Phase 2

Strengthening HPV Immunization Through EPI Leveraged Delivery

HPV Vaccine
International Vaccine Institute115 enrolled1 locationNCT07377656
Recruiting
Phase 2

Infant Malaria Vaccine Schedule Optimization

Malaria Vaccines
PATH964 enrolled2 locationsNCT06879327
Recruiting
Not Applicable

Improving Vaccine Acceptance Through EHR Integrated Patient- and Provider-Facing Decision Support

Vaccine RefusalVaccine Hesitancy
Johns Hopkins Bloomberg School of Public Health1,200 enrolled1 locationNCT06482450
Recruiting
Phase 4

Induction of Cross-protective Antibodies for Serogroup 33 by Pneumococcal Conjugate Vaccines

VaccinePneumococcal disease
University of Alabama at Birmingham70 enrolled1 locationNCT07135453
Recruiting

Genomics and COVID-19 Vaccine Adverse Events

Vaccine Adverse Reaction
University of British Columbia6,325 enrolled1 locationNCT05212792
Recruiting
Not Applicable

Enhancing Maternal Vaccine Knowledge and Uptake: The InTroDuce-Programme Trial

KnowledgeVaccination UptakeInfluenza+3 more
Universiti Putra Malaysia351 enrolled4 locationsNCT06815250
Recruiting

National, Non Interventional Study of Invasive Pneumococcal Disease in Children and Newborns

MortalityPneumococcal InfectionsPneumococcal Conjugate Vaccine+1 more
Association Clinique Thérapeutique Infantile du val de Marne2,500 enrolled1 locationNCT04664556
Recruiting

National Bacterial Meningitis Study in Children and Newborns

MeningitisChildren, OnlyNeonatal Infection+5 more
Association Clinique Thérapeutique Infantile du val de Marne10,000 enrolled1 locationNCT04664569
Recruiting
Phase 3

A Study to Evaluate Immunogenicity and Safety After the First and Second Doses of MG1111 (BARYCELA Inj.) in Healthy Children Aged 12 Months to 12 Years

Varicella (Chickenpox)Chickenpox Vaccine
GC Biopharma Corp474 enrolled1 locationNCT07054099
Recruiting

Comprehensive Characterization of Immune Response Induced by Adjuvanted Glycoprotein E (gE)-Based Recombinant VAccine Zoster in Vulnerable Population Receiving ImmunOmodulaNt Therapies

RZV Vaccine (Shingrix ®)
Fondazione IRCCS Policlinico San Matteo di Pavia150 enrolled1 locationNCT07534007
Recruiting
Phase 4

Comparison of Two Strategies for Administering the R21-Matrix M Vaccine in a Context of Seasonal Malaria Transmission in Chad

Malaria infectionMalaria Vaccines
Epicentre70,000 enrolled1 locationNCT07038837
Recruiting
Phase 1

Clinical Trial of IL - 22BP Safety, Tolerability, and Antitumor Activity in Refractory Solid Tumors.

Refractory Malignant Solid TumorsmRNA VaccineInterleukin
West China Hospital6 enrolled2 locationsNCT07040943