Vestibulodynia Clinical Trials

9 recruitingLast updated: May 13, 2026

There are 9 actively recruiting vestibulodynia clinical trials across 5 countries. Studies span Not Applicable, Phase 2, Phase 3. Top locations include Washington D.C., District of Columbia, United States, New York, New York, United States, Québec, Quebec, Canada. Updated daily from ClinicalTrials.gov.


Vestibulodynia Trials at a Glance

9 actively recruiting trials for vestibulodynia are listed on ClinicalTrialsFinder across 6 cities in 5 countries. The largest study group is Not Applicable with 5 trials, with the heaviest enrollment activity in Washington D.C., New York, and Québec. Lead sponsors running vestibulodynia studies include Center for Vulvovaginal Disorders, Fondazione IRCCS Policlinico San Matteo di Pavia, and Dr Ross Pagano.

Browse vestibulodynia trials by phase

Treatments under study

About Vestibulodynia Clinical Trials

Looking for clinical trials for Vestibulodynia? There are currently 4 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Vestibulodynia trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Vestibulodynia clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 19 of 9 trials

Recruiting
Not Applicable

Efficacy of Dry Needling in Reducing Pain During Sexual Intercourse

Provoked Vestibulodynia
Université de Sherbrooke170 enrolled4 locationsNCT07534345
Recruiting
Not Applicable

Biomodulation and Rehabilitation Interventions to tarGet Pelvic Health

VulvodyniaDyspareuniaProvoked Vestibulodynia
University of Ottawa240 enrolled2 locationsNCT06660212
Recruiting
Phase 2

IncobotulinumtoxinA for Provoked Vestibulodynia With Overactive Pelvic Floor Muscle Dysfunction

Provoked Vestibulodynia
Center for Vulvovaginal Disorders54 enrolled2 locationsNCT07486830
Recruiting
Phase 2

Topical Ketotifen 0.25% for Secondary Vestibulodynia

VulvodyniaProvoked VestibulodyniaSecondary Provoked Vestibulodynia+4 more
Center for Vulvovaginal Disorders54 enrolled3 locationsNCT07257029
Recruiting
Not Applicable

Does a Virtual Program for Pelvic Pain Improve Pain and Sexual Outcomes in Individuals With Provoked Vestibulodynia?

VestibulodyniaVulvodynia (Chronic Vulvar Pain)Vulvar Vestibulitis+2 more
Queen's University250 enrolled1 locationNCT06999395
Recruiting
Not Applicable

VIBRating vs Traditional Therapy for Treatment of ENTry Dyspareunia

DyspareuniaVestibulodyniaPelvic Pain+3 more
Medstar Health Research Institute60 enrolled1 locationNCT06840314
Recruiting

Vestibulodynia At High Resolution: Omics Approach to Improve Diagnosis

VulvodyniaVestibulodynia (VBD)
Fondazione IRCCS Policlinico San Matteo di Pavia400 enrolled1 locationNCT06865963
Recruiting
Not Applicable

Treatment and Mapping of Impostor Phenomenon

Pain SyndromeDermatosesVestibulodynia+1 more
Umeå University20 enrolled2 locationsNCT05805696
Recruiting
Phase 3

Is amitriptyline cream effective in the management of vestibulodynia - a condition which refers to pain at the opening of the vagina?

Vestibulodynia
Dr Ross Pagano50 enrolled1 locationACTRN12612000655842