Weight Clinical Trials

3 recruiting

Weight Trials at a Glance

550 actively recruiting trials for weight are listed on ClinicalTrialsFinder across 6 cities in 61 countries. The largest study group is Not Applicable with 274 trials, with the heaviest enrollment activity in Houston, Dallas, and Miami. Lead sponsors running weight studies include Eli Lilly and Company, Novo Nordisk A/S, and University of Colorado, Denver.

Treatments under study

About Weight Clinical Trials

Looking for clinical trials for Weight? There are currently 3 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Weight trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Weight clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 550 trials

Recruiting
Phase 2

Early Metabolic Effects of Antiretroviral Drugs in Healthy volUnteers: a Phase 2 Randomized Study

Weight GainHealthy VolunteerMetabolic Effects+1 more
National Institute of Allergy and Infectious Diseases (NIAID)120 enrolled1 locationNCT05652478
Recruiting
Phase 3

Efficacy and Safety of KAI-9531 in Participants Living With Obesity or Overweight With Weight-Related Comorbidities Who Do Not Have Diabetes

ObesityOverweight
Kailera1,800 enrolled33 locationsNCT07284875
Recruiting
Phase 2

Investigation of the Efficacy of a Probiotic Mixture in Moderate Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A Mechanistic Trial

MASLD - Metabolic Dysfunction-Associated Steatotic Liver DiseaseFatty Liver Disease, NonalcoholicOverweight (BMI > 25)
AB Biotics, SA60 enrolled1 locationNCT07193927
Recruiting
Phase 3

Efficacy and Safety of KAI-9531 Administered Once Weekly in Participants Living With Obesity or Overweight and Diabetes

Obesity With DiabetesOverweight With Diabetes
Kailera1,700 enrolled37 locationsNCT07284901
Recruiting
Phase 2

Effects of Sucralose on Drug Absorption and Metabolism (The SweetMeds Study)

Healthy VolunteersOverweight
National Institute on Alcohol Abuse and Alcoholism (NIAAA)150 enrolled1 locationNCT03407079
Recruiting
Phase 1

A Study of SYNT-101 to Test Safety, Tolerability and Pharmacodynamics of SYNT-101 in Healthy and Overweight Adults

HealthyOverweight and Obese Adults
Syntis Bio64 enrolled1 locationNCT07307274
Recruiting
Not Applicable

Adaptation of Human Brown Adipose Tissue to Calorie Restriction

Obesity and Overweight
Universidad de Granada30 enrolled1 locationNCT06878989
Recruiting
Phase 2

Effects of Brain Stimulation on Food Intake and Behavioral Weight Loss Treatment

ObesityWeight LossEating+1 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)148 enrolled1 locationNCT00739362
Recruiting
Not Applicable

Adipocyte-Derived Extracellular Vesicles, Weight Loss, and Endothelial Function

ObesityWeight Loss
University of Colorado, Boulder84 enrolled1 locationNCT06776081
Recruiting
Not Applicable

Dyad Plus Effectiveness/Feasibility

Weight LossPediatric ObesityFamily and Household+2 more
Wake Forest University Health Sciences90 enrolled1 locationNCT04036331
Recruiting
Phase 1

Effect of Maridebart Cafraglutide on How Oral Contraceptives Are Absorbed and Processed in the Body in Postmenopausal Female Participants Living With Overweight or Obesity

ObesityOverweight
Amgen45 enrolled3 locationsNCT07523711
Recruiting
Not Applicable

Metabolic and Bio-behavioral Effects of Following Recommendations in the Dietary Guidelines for Americans

ObesityBody Weight
USDA, Western Human Nutrition Research Center70 enrolled1 locationNCT04293224
Recruiting
Not Applicable

Randomized Study on Transoral Outlet Reduction and Lifestyle Changes for Weight Regain After Gastric Bypass

Weight LossWeight Regain
Boston Scientific Corporation108 enrolled9 locationsNCT07015424
Recruiting
Not Applicable

DIStal gastriC Bypass OUtcome in Revision SurgEry After Roux-en-y Gastric Bypass

Weight GainObesity, Morbid
St. Antonius Hospital150 enrolled8 locationsNCT04894838
Recruiting
Not Applicable

Hormonal Control of Energy and Macronutrient Intake in Obesity (MEMORY)

ObesityOverweightNormal Weight
Steno Diabetes Center Copenhagen45 enrolled1 locationNCT06752967
Recruiting

Prevalence, Incidence and Risk Signature of Chronic Kidney Disease in Sub-Saharan Africa

ObesityCardiovascular DiseasesChronic Kidney Diseases+8 more
Swiss Tropical & Public Health Institute1,200 enrolled1 locationNCT05881447
Recruiting
Phase 2

Study of Olatorepatide in Adult Participants Living With Overweight or Obesity in the US

Overweight or Obesity
Regeneron Pharmaceuticals120 enrolled3 locationsNCT07431086
Recruiting
Not Applicable

Effects of Body Composition on Vascular Health in Females With a Healthy Body Weight

BMIStressNormal-weight Obesity
Ball State University30 enrolled1 locationNCT06818500
Recruiting
Phase 2

A Trial to Evaluate Efficacy and Safety of Maridebart Cafraglutide in Adults Living With Elevated Liver Fat and Obesity or Overweight

Overweight or Obesity and Elevated Liver Fat
Amgen180 enrolled15 locationsNCT07441252
Recruiting
Phase 3

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

ObesityOverweightAtherosclerotic Cardiovascular Disease
Amgen12,800 enrolled759 locationsNCT07037433