Tirzepatide Clinical Trials

64 recruitingDrug
Phase 227Phase 417Phase 38Phase 17Not Applicable4Early Phase 14

Showing 120 of 64 trials

Recruiting
Phase 1

Tirzepatide s Dopaminergic Effects in Alcohol Use Disorders (AUD)

Alcohol Use Disorder (AUD)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)176 enrolled1 locationNCT07559500
Recruiting
Phase 1Phase 2

A Study to Evaluate ALN-2232 in Participants With Obesity

Obesity
Alnylam Pharmaceuticals156 enrolled1 locationNCT07463846
Recruiting
Phase 4

Tirzepatide's Role in Postmenopausal HR+ Breast Cancer Survivors

Breast CancerObesity (Disorder)
Weill Medical College of Cornell University30 enrolled1 locationNCT07257484
Recruiting
Phase 2

Tirzepatide in MetALD

Alcohol Use DisorderMetabolic Alcohol-associated Liver Disease
National Institute on Alcohol Abuse and Alcoholism (NIAAA)120 enrolled1 locationNCT07046819
Recruiting
Phase 3

Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

Ulcerative ColitisObesity or Overweight
Eli Lilly and Company350 enrolled189 locationsNCT06937086
Recruiting
Phase 3

A Study of Tirzepatide in Adolescents With Obesity and Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS-2)

ObesityWeight Gain
Eli Lilly and Company300 enrolled72 locationsNCT06439277
Recruiting
Phase 2

A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight

ObesityOverweight
Eli Lilly and Company1,481 enrolled54 locationsNCT06143956
Recruiting
Phase 3

A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)

Metabolic Dysfunction-Associated Steatotic Liver Disease
Eli Lilly and Company4,500 enrolled563 locationsNCT07165028
Recruiting
Phase 2

Evaluation of Tirzepatide as an Adjunct to Buprenorphine for the Treatment of Opioid Use Disorder

Opioid-use DisorderOpioid Use Disorder, ModerateOpioid Use Disorder, Severe
T. John Winhusen, PhD310 enrolled9 locationsNCT06651177
Recruiting
Phase 2

Multi-Site Trial of Tirzepatide for Smoking Cessation

Smoking CessationSmoking Behaviors
University of Southern California300 enrolled4 locationsNCT07602699
Recruiting
Early Phase 1

Effect of Tirzepatide on Markers of MASLD in Patients With Obesity

ObesityMASLD
University of New Mexico8 enrolled1 locationNCT06934642
Recruiting
Phase 2

Study of Tirzepatide for Recovery and Alcohol Use Management

Alcohol Use Disorder (AUD)
Brigham and Women's Hospital20 enrolled2 locationsNCT06727331
Recruiting
Phase 4

A Study of Tirzepatide (LY3298176) Compared With Standard of Care in Adult Participants With Obesity and Without Diabetes (SURMOUNT-REAL UK)

Obesity
Eli Lilly and Company3,000 enrolled30 locationsNCT07247084
Recruiting
Phase 3

Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

Crohn's DiseaseObesity or Overweight
Eli Lilly and Company290 enrolled186 locationsNCT06937099
Recruiting
Phase 1Phase 2

A First-In-Human Study of ARO-INHBE in Adults With Obesity With and Without Type 2 Diabetes Mellitus

Obesity
Arrowhead Pharmaceuticals180 enrolled5 locationsNCT06700538
Recruiting
Phase 2

A Phase 2a Study of ALN-PNP With and Without a GLP1R Agonist in Adult Patients With Homozygous PNPLA3-Related MASLD

Metabolic dysfunction–associated steatotic liver disease (MASLD)
Regeneron Pharmaceuticals204 enrolled5 locationsNCT07527910
Recruiting
Phase 4

A Study to Investigate Effectiveness of Tirzepatide Following Initiation of Ixekizumab in Participants With Active Psoriatic Arthritis and Overweight or Obesity in Clinical Practice (TOGETHER AMPLIFY-PsA)

Psoriatic ArthritisOverweight or Obesity
Eli Lilly and Company200 enrolled55 locationsNCT06864026
Recruiting
Phase 2

Resistance Exercise and Incretin Mimetic for Cardiometabolic Health in Survivors of ALL With Obesity

ObesityAcute Lymphoblastic Leukemia
St. Jude Children's Research Hospital20 enrolled1 locationNCT07228741
Recruiting
Phase 2

Moving Beyond Inflammation as a Therapeutic Target for Crohn's Disease

Crohn Disease (CD)
Washington University School of Medicine60 enrolled3 locationsNCT06976853
Recruiting
Phase 4

The Effect of Tirzepatide on Menopausal Vasomotor Symptoms and Biological Aging in Post-menopausal Women With Obesity

ObesityMenopause Hot Flashes
Mayo Clinic40 enrolled1 locationNCT07218445