Tirzepatide Clinical Trials
51 recruitingDrug
Phase 222Phase 412Phase 37Phase 16Early Phase 13Not Applicable3
Showing 1–20 of 51 trials
Recruiting
Phase 2
Tirzepatide in MetALD
Alcohol Use DisorderMetabolic Alcohol-associated Liver Disease
National Institute on Alcohol Abuse and Alcoholism (NIAAA)120 enrolled1 locationNCT07046819
Recruiting
Phase 2
A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight
ObesityOverweight
Eli Lilly and Company1,217 enrolled54 locationsNCT06143956
Recruiting
Phase 4
Bariatric Surgery vs. Semaglutide vs. Tirzepatide
Obesity and Obesity-related Medical Conditions
Ali Aminian125 enrolled1 locationNCT06803888
Recruiting
Early Phase 1
A Study of a Weight Loss Intervention in People With Endometrial Cancer
Endometrial Cancer
Memorial Sloan Kettering Cancer Center36 enrolled7 locationsNCT06751589
Recruiting
Phase 2
Effect of Tirzepatide and Bimagrumab on Body Composition, Insulin Sensitivity, and Bone in Adults With Obesity
Obesity
Massachusetts General Hospital63 enrolled1 locationNCT05933499
Recruiting
Phase 4
Glucagon-like Peptide-1 Receptor Agonist (GLP-1 RA) and Diet in Inflammatory Bowel Disease (IBD) Patients
Crohn Disease
University of Miami24 enrolled1 locationNCT06774079
Recruiting
Phase 3
Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study
Ulcerative ColitisObesity or Overweight
Eli Lilly and Company350 enrolled193 locationsNCT06937086
Recruiting
Phase 3
A Study of Tirzepatide in Adolescents With Obesity and Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS-2)
ObesityWeight Gain
Eli Lilly and Company300 enrolled75 locationsNCT06439277
Recruiting
Phase 3
Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight
Crohn's DiseaseObesity or Overweight
Eli Lilly and Company290 enrolled188 locationsNCT06937099
Recruiting
Phase 4
The Effect of Tirzepatide on Menopausal Vasomotor Symptoms and Biological Aging in Post-menopausal Women With Obesity
ObesityMenopause Hot Flashes
Mayo Clinic40 enrolled1 locationNCT07218445
Recruiting
Phase 2
Evaluation of Tirzepatide as an Adjunct to Buprenorphine for the Treatment of Opioid Use Disorder
T. John Winhusen, PhD310 enrolled10 locationsNCT06651177
Recruiting
Phase 3
A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)
Metabolic Dysfunction-Associated Steatotic Liver Disease
Eli Lilly and Company4,500 enrolled561 locationsNCT07165028
Recruiting
Phase 4
A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)
PsoriasisOverweight or Obesity
Eli Lilly and Company200 enrolled43 locationsNCT06857942
Recruiting
Phase 4
A Study of Tirzepatide (LY3298176) Compared With Standard of Care in Adult Participants With Obesity and Without Diabetes (SURMOUNT-REAL UK)
Obesity
Eli Lilly and Company3,000 enrolled25 locationsNCT07247084
Recruiting
Phase 3
Efficacy and Safety of Tirzepatide Once Weekly Versus Placebo in Participants Who Are Either Obese or Overweight With Weight-Related Comorbidities (SURMOUNT-1)
ObesityOverweight (Without Type 2 Diabetes) With Weight-related Comorbidities
Hudson Biotech2,539 enrolled1 locationNCT07481747
Recruiting
Phase 3
Comparative Effectiveness of Two Initial Combination Therapies in Patients With Recent Onset Diabetes
Type 2 Diabetes (Adult Onset)
The University of Texas Health Science Center at San Antonio256 enrolled2 locationsNCT06246799
Recruiting
Phase 1Phase 2
A Study to Evaluate ALN-2232 in Participants With Obesity
Obesity
Alnylam Pharmaceuticals156 enrolled1 locationNCT07463846
Recruiting
Phase 1
A Study to Evaluate the Effect of Fasting Duration and Tirzepatide Withholding on the Amount of Food and Fluid in the Stomach in Participants With Type 2 Diabetes Mellitus and Participants With Overweight or Obesity Without Type 2 Diabetes Mellitus
ObesityDiabetes Mellitus, Type 2Overweight
Eli Lilly and Company40 enrolled1 locationNCT07299084
Recruiting
Early Phase 1
Pre-Surgical Tirzepatide-Assisted Weight Loss in Overweight and Obese Men With Intermediate Risk Prostate Cancer: A Pilot Feasibility Study
Prostate CancerDiabetes
M.D. Anderson Cancer Center30 enrolled1 locationNCT06759701
Recruiting
Phase 1
Pathways, Risk Factors, and mOleculeS to Prevent Early-onset Colorectal Tumors
Colorectal AdenomaColorectal Cancer Prevention
Massachusetts General Hospital20 enrolled1 locationNCT07095517