Entrectinib Clinical Trials
11 recruitingDrug
Phase 28Phase 33
Showing 1–11 of 11 trials
Recruiting
Phase 2
Entrectinib as a Single Agent in Upfront Therapy for Children <3 Years of Age With NTRK1/2/3 or ROS1-FUSED CNS Tumors
CNS TumorHigh Grade Glioma
St. Jude Children's Research Hospital52 enrolled4 locationsNCT06528691
Recruiting
Phase 3
A Rollover Study for Participants Previously Enrolled in a Genentech and/or F. Hoffman-La Roche Sponsored Study
Cancer
Hoffmann-La Roche100 enrolled57 locationsNCT05862285
Recruiting
Phase 2
A Study of Multiple Therapies in Biomarker-selected Participants With Resectable Stages IB-III Non-small Cell Lung Cancer (NSCLC)
Non-small Cell Lung Cancer
Genentech, Inc.99 enrolled38 locationsNCT04302025
Recruiting
Phase 2
Tumor-agnostic Precision Immuno-oncology and Somatic Targeting Rational for You (TAPISTRY) Platform Study
Solid Tumors
Hoffmann-La Roche920 enrolled163 locationsNCT04589845
Recruiting
Phase 2Phase 3
DETERMINE Trial Treatment Arm 03: Entrectinib in Adult, Paediatric and Teenage/Young Adult Patients With ROS1 Gene Fusion-Positive Cancers.
MalignancyMelanomaCancer+8 more
Cancer Research UK30 enrolled27 locationsNCT05770544
Recruiting
Phase 2Phase 3
DETERMINE (Determining Extended Therapeutic Indications for Existing Drugs in Rare Molecularly Defined Indications Using a National Evaluation Platform Trial) - Master Screening Protocol
Haematological MalignancySolid Tumour
Cancer Research UK825 enrolled27 locationsNCT05722886
Recruiting
Study on the Mechanism of Acquired Resistance of Entrectinib
ROS1 Fusion Positive
Fudan University38 enrolled1 locationNCT07199959
Recruiting
KPMNG Study of MOlecular Profiling Guided Therapy Based on Genomic Alterations in Advanced Solid Tumors II
Advanced Solid TumorMetastatic CancerSolid Tumor
Seoul National University Bundang Hospital1,000 enrolled32 locationsNCT05525858
Recruiting
Phase 2
Efficacy of Organoid-Based Drug Screening to Guide Treatment for Locally Advanced Thyroid Cancer
Locally Advanced Thyroid Gland Carcinoma
West China Hospital75 enrolled1 locationNCT06482086
Recruiting
Phase 2
The Finnish National Study to Facilitate Patient Access to Targeted Anti-cancer Drugs
Advanced CancerSolid TumorHaematological Malignancy
Helsinki University Central Hospital250 enrolled5 locationsNCT05159245
Recruiting
Phase 2
The Drug Rediscovery Protocol (DRUP Trial)
CancerNeoplasmNeoplasia+1 more
The Netherlands Cancer Institute1,550 enrolled36 locationsNCT02925234