Leflunomide Clinical Trials

12 recruitingDrug
Phase 14Phase 23Not Applicable2Phase 31Phase 41

Showing 112 of 12 trials

Recruiting
Phase 3

Treatment of Rheumatoid Arthritis With DMARDs: Predictors of Response

Rheumatoid Arthritis
University of Nebraska400 enrolled1 locationNCT03414502
Recruiting
Phase 2

Leflunomide, Pomalidomide, and Dexamethasone for the Treatment of Relapsed or Refractory Multiple Myeloma

Recurrent Plasma Cell MyelomaRefractory Plasma Cell Myeloma
City of Hope Medical Center29 enrolled1 locationNCT04508790
Recruiting
Phase 1

Leflunomide in Combination With Steroids for the Treatment of Acute Graft-versus-Host Disease After Donor Stem Cell Transplant for Hematologic Malignancies

Acute Graft Versus Host DiseaseHematopoietic and Lymphoid System Neoplasm
City of Hope Medical Center18 enrolled1 locationNCT05443425
Recruiting
Phase 1

Leflunomide in Patients With PTEN-Altered Advanced Solid Malignancies and HER2 Negative Breast Cancer

PTEN-Altered Advanced Solid Tumors and HER2 Negative Breast Cancer
Deborah Doroshow24 enrolled1 locationNCT04997993
Recruiting
Phase 1

Gemcitabine and Leflunomide in Patients With Advanced Unresectable Pancreatic Cancer

Stage III Pancreatic Cancer AJCC v8Stage IV Pancreatic Cancer AJCC v8Advanced Pancreatic Adenocarcinoma+1 more
City of Hope Medical Center19 enrolled1 locationNCT06454383
Recruiting

CHronic Nonbacterial Osteomyelitis International Registry

Chronic Recurrent Multifocal OsteomyelitisChronic Nonbacterial Osteomyelitis
Seattle Children's Hospital2,000 enrolled1 locationNCT04725422
Recruiting
Not Applicable

Treatment Strategies for IgG4-RD Patients With Internal Organ Involvement

Autoimmune Diseases
Peking Union Medical College Hospital60 enrolled1 locationNCT05789017
Recruiting
Phase 2

Leflunomide or Combination of MEK Inhibitor and Hydroxychloroquine for Refractory Patients With RAS Mutations

Lung CancerMelanomaPancreas Cancer+4 more
N.N. Petrov National Medical Research Center of Oncology20 enrolled1 locationNCT06229340
Recruiting
Not Applicable

Leflunomide for Henoch-Schonlein Purpura

Henoch-Schonlein Purpura
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University36 enrolled1 locationNCT05937880
Recruiting
Phase 1Phase 2

Leflunomide for Idiopathic Pulmonary Hemosiderosis in Children

Idiopathic Pulmonary HemosiderosisLeflunomide
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University34 enrolled1 locationNCT05937191
Recruiting
Phase 4

The Clinical Efficacy of Immunomodulators in RA Patients

Arthritis, Rheumatoid
Qilu Hospital of Shandong University400 enrolled1 locationNCT05626348
Recruiting

The Registry Study of Takayasu Arteritis in East China

Treatment RefusalPregnancy RelatedTakayasu Arteritis+2 more
Shanghai Zhongshan Hospital1,000 enrolled1 locationNCT03893136