RecruitingEarly Phase 1NCT06934642

Effect of Tirzepatide on Markers of MASLD in Patients With Obesity

Effect of Tirzepatide on Markers of MASLD in Patients With Obesity: A Pilot Study


Sponsor

University of New Mexico

Enrollment

8 participants

Start Date

Jun 30, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) is the most common cause of chronic liver disease worldwide and predominately affects individuals with overweight and obesity, as well as those with type 2 diabetes and cardiovascular disease. Tirzepatide is a medication used to treat type 2 diabetes and obesity. It has also been shown to help with MASLD. The purpose of this study is to study how tirzepatide affects the liver in patients with MASLD. Participants will be asked to: * Take tirzepatide for 12 months. * Come in for clinic visits every 3 months. * Have blood drawn at baseline, 6, and 12 months. * Complete a liver ultrasound at baseline and at 12 months.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Tirzepatide for people with masld and obesity. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGTirzepatide

The drug is being studied to better understand the biological effects of tirzepatide on MASLD.


Locations(1)

University of New Mexico Health Sciences Center

Albuquerque, New Mexico, United States

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NCT06934642


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