The Hospital for Sick Children
Toronto, Ontario, Canada
24 recruiting
Showing 1–20 of 24 trials
Recruiting
Phase 3
A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids)
Chronic Kidney Disease
Boehringer Ingelheim120 enrolled102 locationsNCT07107945
Recruiting
Phase 1Phase 2
A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation
Acute Lymphoblastic LeukemiaAcute Myeloid LeukemiaMixed Phenotype Acute Leukemia+2 more
Syndax Pharmaceuticals447 enrolled57 locationsNCT04065399
Recruiting
Phase 3
A Study of Mirikizumab (LY3074828) in Pediatric Participants With Crohn's Disease
Crohn's Disease
Eli Lilly and Company90 enrolled81 locationsNCT05509777
Recruiting
Phase 3
A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)
Inflammatory Bowel DiseasesCrohn's DiseaseUlcerative Colitis+1 more
Eli Lilly and Company150 enrolled63 locationsNCT04844606
Recruiting
Phase 3
A Study of Mirikizumab (LY3074828) in Pediatric Participants With Moderately to Severely or Active Ulcerative Colitis
Ulcerative Colitis
Eli Lilly and Company60 enrolled34 locationsNCT05784246
Recruiting
Phase 2
Xenon-129 and Inert Fluorinated Gas Lung MRI: Study of Healthy Volunteers and Participants With Pulmonary Disease
AsthmaCystic Fibrosis
The Hospital for Sick Children30 enrolled1 locationNCT02740868
Recruiting
Early Phase 1
Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation
NeuroblastomaPineoblastomaAtypical Teratoid/Rhabdoid Tumor+11 more
C17 Council15 enrolled12 locationsNCT06942039
Recruiting
Phase 2
Naxitamab for High-Risk Neuroblastoma Patients With Primary Refractory Disease or Incomplete Response to Salvage Treatment in Bone and/or Bone Marrow
Neuroblastoma
Y-mAbs Therapeutics122 enrolled26 locationsNCT03363373
Recruiting
Phase 1Phase 2
Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing Sarcoma
Recurrent Malignant Solid NeoplasmRefractory Malignant Solid NeoplasmRecurrent Solid Tumor+19 more
St. Jude Children's Research Hospital90 enrolled10 locationsNCT04901702
Recruiting
Phase 1Phase 2
Study of Lurbinectedin Monotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Ewing Sarcoma
Ewing SarcomaRefractory Ewing SarcomaRelapsed Ewing Sarcoma
Jazz Pharmaceuticals60 enrolled15 locationsNCT05734066
Recruiting
Phase 1Phase 2
Optimal Precision TherapIes to CustoMISE Care in Childhood and Adolescent Cancer
Refractory CancerRecurrent CancerChildhood Cancer+2 more
Australian & New Zealand Children's Haematology/Oncology Group90 enrolled14 locationsNCT06208657
Recruiting
Phase 3
Effect of Metformin on Behaviour and the Brain in Children Treated for a Brain Tumour
Cognitive ImpairmentMedulloblastoma, Childhood
Donald Mabbott140 enrolled20 locationsNCT05230758
Recruiting
Phase 3
Magnesium Trial in Acute Asthma in Emergency Department
Asthma
Suzanne Schuh192 enrolled6 locationsNCT06785272
Recruiting
CfDNA in Hereditary And High-risk Malignancies 2
Hereditary Cancer Syndrome
University Health Network, Toronto1,000 enrolled8 locationsNCT06726642
Recruiting
Phase 1
CLIC-2201 for the Treatment of Relapsed/Refractory B Cell Malignancies
Diffuse Large B Cell LymphomaHigh-grade B-cell LymphomaMantle Cell Lymphoma+5 more
British Columbia Cancer Agency24 enrolled7 locationsNCT06208735
Recruiting
Not Applicable
Transforming Care for Individuals With Childhood-onset Systemic Lupus Erythematosus
Systemic Lupus Erythematosus of Childhood (Disorder)
Michigan State University175 enrolled7 locationsNCT06232304
Recruiting
Observational Study of Pediatric Rheumatic Diseases: The CARRA Registry
Rheumatic Joint Disease
Duke University20,000 enrolled82 locationsNCT02418442
Recruiting
Phase 1Phase 2
A Phase I Double Blind Study of Metformin Acting on Endogenous Neural Progenitor Cells in Children and Young Adults With Multiple Sclerosis
Multiple Sclerosis (MS)
The Hospital for Sick Children20 enrolled1 locationNCT04121468
Recruiting
Not Applicable
iP2P Mentorship Program for Adolescent HF Patients
Heart Failure
The Hospital for Sick Children55 enrolled1 locationNCT05709132
Recruiting
TrialNet Pathway to Prevention of T1D
Diabetes Mellitus, Type 1
University of South Florida75,000 enrolled22 locationsNCT00097292