The Hospital for Sick Children
Toronto, Ontario, Canada
24 recruiting
Showing 1–20 of 108 trials
Recruiting
Phase 2
A Study of TYRA-300 in Children With Achondroplasia: BEACH301
Achondroplasia
Tyra Biosciences, Inc92 enrolled22 locationsNCT06842355
Recruiting
Not Applicable
Feasibility of a Diet Intervention for Juvenile Arthritis
Juvenile Idiopathic ArthritisArthritis, JuvenileArthritis, Childhood
The Hospital for Sick Children54 enrolled7 locationsNCT06474546
Recruiting
Phase 2
Phase 2b Study of RPT904 as Monotherapy in Participants With IgE-Mediated Food Allergy
Ig-E Mediated Food Allergy
RAPT Therapeutics, Inc.100 enrolled36 locationsNCT07220811
Recruiting
Phase 3
A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids)
Chronic Kidney Disease
Boehringer Ingelheim120 enrolled102 locationsNCT07107945
Recruiting
Phase 3
A Study to Find Out How Nerandomilast is Tolerated, Handled by the Body, and if it Helps Children and Adolescents With Interstitial Lung Disease (FIBRONEER-chILD)
Fibrosing Interstitial Lung Disease
Boehringer Ingelheim35 enrolled48 locationsNCT07366034
Recruiting
Phase 3
A Phase 3 Trial to Compare IV BCV Versus IV CDV for Treatment of Adenovirus Infection After Allo-HCT
Adenovirus Infections
SymBio Pharmaceuticals180 enrolled81 locationsNCT07387367
Recruiting
Phase 1Phase 2
Study of ASP2957 in Male Participants With X-linked Myotubular Myopathy Who Need Ventilators
X-linked Myotubular Myopathy
Astellas Gene Therapies9 enrolled4 locationsNCT07052929
Recruiting
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
Heart FailurePainInsomnia+22 more
Duke University5,000 enrolled51 locationsNCT04278404
Recruiting
Early Phase 1
Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation
NeuroblastomaPineoblastomaAtypical Teratoid/Rhabdoid Tumor+11 more
C17 Council15 enrolled12 locationsNCT06942039
Recruiting
Primary Sclerosing Cholangitis in Children
Liver DiseasesPrimary Sclerosing CholangitisCholangitis, Sclerosing
Arbor Research Collaborative for Health1,000 enrolled12 locationsNCT04181138
Recruiting
Not Applicable
Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)
Cardiac Arrest, Out-Of-HospitalHypoxia-Ischemia, BrainHypothermia, Induced
University of Michigan900 enrolled62 locationsNCT05376267
Recruiting
Phase 3
A Study to Assess the Efficacy and Safety of Emicizumab in Participants With Type 3 Von Willebrand Disease
Von Willebrand Disease, Type 3
Hoffmann-La Roche75 enrolled28 locationsNCT06998524
Recruiting
Cohort Network for Adolescents and Youth With multipLe Mental Health Conditions
Child Mental HealthMultiple Mental Health ConditionsYouth mental health
Centre for Addiction and Mental Health1,620 enrolled6 locationsNCT07699159
Recruiting
Phase 1Phase 2
A Study of SGT-003 Gene Therapy in Duchenne Muscular Dystrophy (INSPIRE DUCHENNE)
Duchenne Muscular Dystrophy
Solid Biosciences Inc.60 enrolled15 locationsNCT06138639
Recruiting
Phase 1Phase 2
A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Alectinib in Pediatric Participants With ALK Fusion-Positive Solid or CNS Tumors
ALK Fusion-positive Solid or CNS Tumors
Hoffmann-La Roche42 enrolled33 locationsNCT04774718
Recruiting
Phase 2
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants
Lupus Nephritis
Hoffmann-La Roche40 enrolled42 locationsNCT05039619
Recruiting
Phase 3
A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrome
Dravet Syndrome
Epygenix150 enrolled60 locationsNCT04462770
Recruiting
Phase 3
A Research Study Looking at Long-term Treatment With Mim8 in People With Haemophilia A
Haemophilia AHaemophilia A With Inhibitors
Novo Nordisk A/S451 enrolled152 locationsNCT05685238
Recruiting
Not Applicable
MedlyPeds Feasibility Study
Post-cardiac surgeryPulmonary HypertensionCongenital Heart Disease (CHD)+2 more
The Hospital for Sick Children30 enrolled1 locationNCT07556185
Recruiting
Phase 2
A Study of CC-97540 (BMS-986353 or Zola-cel), CD19-Targeted NEX-T CAR T Cells, in Participants With Active SLE Despite Immunosuppressants (Breakfree-SLE)
Lupus Erythematosus, SystemicLupus Nephritis
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company89 enrolled96 locationsNCT07015983