The Hospital for Sick Children
Toronto, Ontario, Canada
24 recruiting
Showing 1–20 of 105 trials
Recruiting
Childhood Cancer Survivor Study
Cancer
St. Jude Children's Research Hospital50,000 enrolled31 locationsNCT01120353
Recruiting
Phase 2Phase 3
Open-label, Long-term Safety, Efficacy, and Pharmacokinetics Study of Vibegron in Pediatric Subjects 2 Years to < 18 Years of Age With NDO and on CIC
neurogenic detrusor overactivity
Urovant Sciences GmbH71 enrolled38 locationsNCT05491525
Recruiting
Phase 3
A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids)
Chronic Kidney Disease
Boehringer Ingelheim120 enrolled102 locationsNCT07107945
Recruiting
Phase 1Phase 2
CANnabinoids in Pediatric ONCology
CancerChildhood Cancer
University of Manitoba60 enrolled3 locationsNCT05754840
Recruiting
Phase 3
A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia
Sickle Cell DiseaseThalassemia
Novo Nordisk A/S480 enrolled105 locationsNCT06609226
Recruiting
Phase 1Phase 2
Phase 1/2 Study of Mirdametinib + Vinblastine for Newly Diagnosed/Previously Untreated PLGG + Activation of MAPK
Pediatric Low-grade Glioma
St. Justine's Hospital50 enrolled8 locationsNCT06666348
Recruiting
Phase 2
A Study of TYRA-300 in Children With Achondroplasia: BEACH301
Achondroplasia
Tyra Biosciences, Inc92 enrolled17 locationsNCT06842355
Recruiting
Phase 3
A Study to Evaluate the Drug Levels, Efficacy and Safety of Deucravacitinib in Children and Adolescent Participants With Moderate to Severe Plaque Psoriasis
Plaque Psoriasis
Bristol-Myers Squibb153 enrolled63 locationsNCT04772079
Recruiting
Early Phase 1
Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation
NeuroblastomaPineoblastomaAtypical Teratoid/Rhabdoid Tumor+11 more
C17 Council15 enrolled12 locationsNCT06942039
Recruiting
Phase 1Phase 2
A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Alectinib in Pediatric Participants With ALK Fusion-Positive Solid or CNS Tumors
ALK Fusion-positive Solid or CNS Tumors
Hoffmann-La Roche42 enrolled33 locationsNCT04774718
Recruiting
Not Applicable
Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)
Cardiac Arrest, Out-Of-HospitalHypoxia-Ischemia, BrainHypothermia, Induced
University of Michigan900 enrolled61 locationsNCT05376267
Recruiting
A Prospective Database of Infants With Cholestasis
Biliary Atresia
Arbor Research Collaborative for Health1,000 enrolled16 locationsNCT00061828
Recruiting
Phase 2
Phase 2b Study of RPT904 as Monotherapy in Participants With IgE-Mediated Food Allergy
Ig-E Mediated Food Allergy
RAPT Therapeutics, Inc.100 enrolled31 locationsNCT07220811
Recruiting
Primary Sclerosing Cholangitis in Children
Liver DiseasesPrimary Sclerosing CholangitisCholangitis, Sclerosing
Arbor Research Collaborative for Health1,000 enrolled12 locationsNCT04181138
Recruiting
Phase 3
A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)
Inflammatory Bowel DiseasesCrohn's DiseaseUlcerative Colitis+1 more
Eli Lilly and Company150 enrolled67 locationsNCT04844606
Recruiting
Phase 2
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants
Lupus Nephritis
Hoffmann-La Roche40 enrolled42 locationsNCT05039619
Recruiting
Phase 2
A Study of CC-97540 (BMS-986353 or Zola-cel), CD19-Targeted NEX-T CAR T Cells, in Participants With Active SLE Despite Immunosuppressants (Breakfree-SLE)
Lupus Erythematosus, SystemicLupus Nephritis
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company89 enrolled95 locationsNCT07015983
Recruiting
Phase 1Phase 2
Study of ASP2957 in Male Participants With X-linked Myotubular Myopathy Who Need Ventilators
X-linked Myotubular Myopathy
Astellas Gene Therapies9 enrolled4 locationsNCT07052929
Recruiting
Phase 3
A Study of Mirikizumab (LY3074828) in Pediatric Participants With Crohn's Disease
Crohn's Disease
Eli Lilly and Company90 enrolled81 locationsNCT05509777
Recruiting
Phase 1Phase 2
Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing Sarcoma
Recurrent Malignant Solid NeoplasmRefractory Malignant Solid NeoplasmRecurrent Solid Tumor+19 more
St. Jude Children's Research Hospital90 enrolled10 locationsNCT04901702