The Hospital for Sick Children
Toronto, Ontario, Canada
24 recruiting
Showing 1–20 of 101 trials
Recruiting
Phase 2
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants
Lupus Nephritis
Hoffmann-La Roche40 enrolled42 locationsNCT05039619
Recruiting
Phase 1Phase 2
A Study of Subcutaneous Blinatumomab Administration in Participants With R/R and MRD+ B-ALL
B Cell Precursor Acute Lymphoblastic Leukemia
Amgen281 enrolled109 locationsNCT04521231
Recruiting
Phase 3
Study to Evaluate Efficacy and Safety of Romosozumab Compared With Bisphosphonates in Children and Adolescents With Osteogenesis Imperfecta
Osteogenesis Imperfecta
Amgen106 enrolled65 locationsNCT05972551
Recruiting
Phase 3
Effect of Metformin on Behaviour and the Brain in Children Treated for a Brain Tumour
Cognitive ImpairmentMedulloblastoma, Childhood
Donald Mabbott140 enrolled20 locationsNCT05230758
Recruiting
Phase 3
A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids)
Chronic Kidney Disease
Boehringer Ingelheim120 enrolled102 locationsNCT07107945
Recruiting
Not Applicable
Complete Cognitive Intervention for cSLE
Lupus
Andrea Knight60 enrolled1 locationNCT07302113
Recruiting
Anesthetics and Analgesics in Children
PainAnesthesia
Chi Dang Hornik500 enrolled13 locationsNCT03427736
Recruiting
Not Applicable
PromotIng Optimal Treatment for Community-acquired PNeumonia in EmErgency Rooms
PneumoniaCommunity-Acquired Pneumonia (CAP)
Jeffrey Pernica698 enrolled6 locationsNCT07099976
Recruiting
Phase 3
A Phase 3 Trial to Compare IV BCV Versus IV CDV for Treatment of Adenovirus Infection After Allo-HCT
Adenovirus Infections
SymBio Pharmaceuticals180 enrolled61 locationsNCT07387367
Recruiting
Childhood Cancer Survivor Study
Cancer
St. Jude Children's Research Hospital50,000 enrolled31 locationsNCT01120353
Recruiting
Phase 2
A Study to Evaluate the Pharmacokinetics and Safety of Etavopivat in Pediatric Patients With Sickle Cell Disease
Sickle Cell Disease
Forma Therapeutics, Inc.95 enrolled18 locationsNCT06198712
Recruiting
Phase 2
A Study of TYRA-300 in Children With Achondroplasia: BEACH301
Achondroplasia
Tyra Biosciences, Inc92 enrolled15 locationsNCT06842355
Recruiting
Not Applicable
PACT Involvement in Cardiology Patients
Machine LearningPediatric Palliative CareCardiovascular Outcome+1 more
The Hospital for Sick Children1,000 enrolled1 locationNCT06886529
Recruiting
Adaptive Optics Retinal Imaging in Inherited and Acquired Retinal Disorders
Genetic DiseaseInherited Disease
The Hospital for Sick Children200 enrolled1 locationNCT05386134
Recruiting
Not Applicable
Online Support 4 CHD Kids & Caregivers
Congenital Heart Disease
The Hospital for Sick Children382 enrolled1 locationNCT06075251
Recruiting
Phase 3
A Study to Assess the Efficacy and Safety of Emicizumab in Participants With Type 3 Von Willebrand Disease
Von Willebrand Disease, Type 3
Hoffmann-La Roche75 enrolled27 locationsNCT06998524
Recruiting
An Observational Study of Participants With Type 3 Von Willebrand Disease on Prophylactic Standard-of-Care Treatment
Von Willebrand Disease, Type 3
Hoffmann-La Roche40 enrolled27 locationsNCT06883240
Recruiting
Phase 3
A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)
Inflammatory Bowel DiseasesCrohn's DiseaseUlcerative Colitis+1 more
Eli Lilly and Company150 enrolled66 locationsNCT04844606
Recruiting
Phase 1Phase 2
Study of ASP2957 in Male Participants With X-linked Myotubular Myopathy Who Need Ventilators
Astellas Gene Therapies9 enrolled4 locationsNCT07052929
Recruiting
Phase 3
A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Satralizumab in Participants With Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease
Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD)
Hoffmann-La Roche152 enrolled82 locationsNCT05271409