Clinical Trials in Durban, KwaZulu-Natal

36 recruiting

Showing 120 of 27 trials

Recruiting
Phase 1

Safety and Immunogenicity Study of Three mRNAs Encoding HIV Immunogens in Adult Participants Without HIV and in Overall Good Health in South Africa.

HIV Infections
International AIDS Vaccine Initiative96 enrolled6 locationsNCT06694753
Recruiting
Phase 3

A Study of Quabodepistat-containing Regimens for the Treatment of Drug-resistant Pulmonary Tuberculosis

Pulmonary Tuberculosis
Otsuka Pharmaceutical Development & Commercialization, Inc.532 enrolled35 locationsNCT07209761
Recruiting
Phase 3

A Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-010)

Human Immunodeficiency Virus (HIV)HIV Pre-Exposure Prophylaxis
Merck Sharp & Dohme LLC4,580 enrolled30 locationsNCT07071623
Recruiting
Phase 2

A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate-To-Severe Asthma

Asthma
Pfizer252 enrolled132 locationsNCT06977581
Recruiting
Phase 2Phase 3

A Clinical Study of Islatravir and Ulonivirine for People With HIV-1 Who Have Not Been Treated Before (MK-8591B-062)

Human Immunodeficiency Virus Type 1 (HIV-1) Infection
Merck Sharp & Dohme LLC570 enrolled49 locationsNCT07266831
Recruiting
Not Applicable

A Study to Evaluate the Performance, Usability, and Contrived Result Interpretation of iStatis Gonorrhea Antigen Test

Gonorrhea Infection
bioLytical Laboratories650 enrolled3 locationsNCT07569900
Recruiting
Not Applicable

A Study to Evaluate Performance, Usability, and Contrived Result Interpretation of TruPlex HIV/HepB/Syphilis Rapid Test

hepatitis B infectionHIV-1-infectionSyphilis Infection+1 more
bioLytical Laboratories1,000 enrolled3 locationsNCT07563309
Recruiting
Phase 1Phase 2

Very Early Intensive Treatment of Infants Living With HIV to Achieve HIV Remission

HIV Infection
National Institute of Allergy and Infectious Diseases (NIAID)1,120 enrolled46 locationsNCT02140255
Recruiting
Phase 2

Doravirine (DOR) in Human Immunodeficiency Virus (HIV)-Infected Children Aged 4 Weeks to <12 Years and <45 kg (MK-1439-066)

Human Immunodeficiency Virus (HIV) Infection
Merck Sharp & Dohme LLC84 enrolled24 locationsNCT04375800
Recruiting
Phase 3

Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

Solid TumorsHematologic Malignancies
Merck Sharp & Dohme LLC3,500 enrolled779 locationsNCT03486873
Recruiting
Phase 2

A Study to Assess the Safety and Efficacy of Different Doses of ELV001 to Treat Active Rheumatoid Arthritis in Patients With an Inadequate Response to Methotrexate and Tumor Necrosis Factor Inhibition (START SYNERGY)

Active Rheumatoid Arthritis
Elevara Medicines Limited180 enrolled29 locationsNCT07409103
Recruiting
Phase 3

A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)

Non-small Cell Lung Cancer MetastaticNon-Small-Cell Lung CarcinomaNon-small Cell Carcinoma
Pfizer680 enrolled305 locationsNCT07144280
Recruiting
Phase 3

A Clinical Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-011)

Human Immunodeficiency Virus (HIV)HIV Pre-Exposure Prophylaxis
Merck Sharp & Dohme LLC4,390 enrolled78 locationsNCT07044297
Recruiting

National Blood Pressure Screening in Children to Improve Paediatric Healthcare in South Africa

HypertensionObesity, ChildhoodObesity, Adolescent
North-West University, South Africa22,464 enrolled11 locationsNCT05982847
Recruiting
Not Applicable

Evaluation of Long-Acting Injectable (LAI) and Teen Clubs in Adolescents (ATTUNE).

HIV
Africa Health Research Institute720 enrolled12 locationsNCT06721078
Recruiting
Not Applicable

HIV Self-testing for Partners of HIV-uninfected Postpartum Women

FeasibilityHIV PreventionPrEP Uptake+3 more
Massachusetts General Hospital120 enrolled1 locationNCT07194902
Recruiting
Phase 3

A Study to Assess Disease Activity and Safety of Lutikizumab in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa

Hidradenitis Suppurativa
AbbVie1,280 enrolled279 locationsNCT06468228
Recruiting
Phase 2

Evaluating the Safety and Immunogenicity of MTBVAC

TuberculosisHIV I Infection
HIV Vaccine Trials Network276 enrolled16 locationsNCT05947890
Recruiting
Phase 3

A Study of Subcutaneously Injected Epcoritamab Plus Oral Lenalidomide Tablets Compared to Intravenously (IV) Infused Rituximab Plus IV Infused Gemcitabine and IV Infused Oxaliplatin in Adult Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Genmab360 enrolled177 locationsNCT06508658
Recruiting
Phase 2

A Long-Term Safety and Efficacy Study of Verekitug (UPB-101) in Adult Participants With Severe Asthma (VALOUR)

Severe Asthma
Upstream Bio Inc.436 enrolled84 locationsNCT06966479