Clinical Trials in Manchester, Greater Manchester

18 recruiting

Showing 118 of 18 trials

Recruiting
Phase 3

CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis

Transthyretin Amyloid Cardiomyopathy (ATTR CM)
Novo Nordisk A/S1,280 enrolled285 locationsNCT07207811
Recruiting
Phase 3

A Study to Learn More About How Safe the Study Treatment Finerenone is in Long-term Use When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker Over 18 Months of Use in Children and Young Adults From 1 to 18 Years of Age With Chronic Kidney Disease and Proteinuria

Chronic Kidney DiseaseProteinuriaChildren
Bayer100 enrolled178 locationsNCT05457283
Recruiting

The Tommy's National Rainbow Clinic Study

Stillbirth
University of Manchester500 enrolled1 locationNCT04393259
Recruiting
Phase 2

A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate-To-Severe Asthma

Asthma
Pfizer252 enrolled125 locationsNCT06977581
Recruiting
Phase 3

A Study to Learn More About How Well the Study Treatment Finerenone Works, How Safe it is, How it Moves Into, Through, and Out of the Body, and the Effects it Has on the Body When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker in Children With Chronic Kidney Disease and Proteinuria

Chronic Kidney DiseaseProteinuria
Bayer219 enrolled154 locationsNCT05196035
Recruiting
Phase 3

A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma

Brain TumorGlioblastomaGBM+1 more
Ivy Brain Tumor Center450 enrolled93 locationsNCT06388733
Recruiting
Phase 1

PAveMenT: Palbociclib and Avelumab in Metastatic AR+ Triple Negative Breast Cancer

Royal Marsden NHS Foundation Trust45 enrolled9 locationsNCT04360941
Recruiting

A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)

Obstructive Hypertrophic Cardiomyopathy
Bristol-Myers Squibb1,600 enrolled99 locationsNCT05489705
Recruiting

Detecting EARLY Heart Failure in Greater Manchester

Heart Failure
Manchester University NHS Foundation Trust600 enrolled1 locationNCT05955456
Recruiting
Not Applicable

Real-world Elecsys® GAAD Implementation and Validation to Improve Surveillance and Early Detection of HCC

Hepatocellular CarcinomaLiver Cirrhosis
Manchester University NHS Foundation Trust600 enrolled1 locationNCT05971108
Recruiting
Phase 1Phase 2

A Study to Evaluate Safety, Drug Levels and Effectiveness of CC-92480 (BMS-986348) in Combination With Other Treatments in Participants With Relapsed or Refractory Multiple Myeloma

Multiple Myeloma
Bristol-Myers Squibb260 enrolled17 locationsNCT05372354
Recruiting

HIV and Changes in the Gut Microbiome After Changes in Antiretroviral Therapy (ART)

HIV Infections
University of Manchester15 enrolled1 locationNCT06100211
Recruiting

Biomarkers for Clinical Hypoxia Evaluation in Cervical Cancer

Cervical Cancer
University of Manchester30 enrolled1 locationNCT05029258
Recruiting

Chronic Radiation Induced Bowel Toxicity Study

Prostate Cancer
The Christie NHS Foundation Trust50 enrolled2 locationsNCT06640959
Recruiting
Phase 2

Diagnostic Accuracy Study for OWL-EVO1 As a Lung Cancer EVOC® Probe (Evolution Phase 2)

Lung Cancer
Owlstone Ltd350 enrolled9 locationsNCT06193239
Recruiting

Tracking Mutations in Cell Free Tumour DNA to Predict Relapse in Early Colorectal Cancer

Colorectal, Cancer
Royal Marsden NHS Foundation Trust1,000 enrolled71 locationsNCT04050345
Recruiting
Not Applicable

Improving Access and Recruitment to Clinical Trials for Lung Cancer Patients

Lung Cancer
Oxford Brookes University100 enrolled9 locationsNCT05888584
Recruiting
Not Applicable

Role of Fasted Exercise on Improving Cardiometabolic Health

ObesityCardiovascular DiseasesDiabetes Mellitus, Type 2
Manchester Metropolitan University30 enrolled1 locationNCT05742373