Clinical Trials in Plymouth, Devon

24 recruiting

Showing 120 of 20 trials

Recruiting
Phase 3

A Study to Compare Linvoseltamab Monotherapy and Linvoseltamab + Carfilzomib Combination Therapy With Standard-of-Care Combination Regimens in Adult Participants With Relapsed/Refractory Multiple Myeloma (RRMM)

Relapsed and/or Refractory Multiple Myeloma (RRMM)
Regeneron Pharmaceuticals915 enrolled16 locationsNCT07222761
Recruiting
Phase 3

A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab on Background Topical Corticosteroids Therapy in Participants Aged 12 Years and Older With Moderate-to-severe AD Who Have Had an Inadequate Response to Prior Biologic Therapy or an Oral JAK Inhibitor

Dermatitis Atopic
Sanofi636 enrolled147 locationsNCT06241118
Recruiting
Phase 3

Long-Term Safety and Efficacy of Plozasiran in Adults With Hypertriglyceridemia

Hypertriglyceridemia
Arrowhead Pharmaceuticals869 enrolled248 locationsNCT06822790
Recruiting
Phase 2

A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)

Lymphoma, Large B-Cell, Diffuse
Merck Sharp & Dohme LLC594 enrolled123 locationsNCT06890884
Recruiting
Phase 3

A Trial to Find Out if Odronextamab Combined With Lenalidomide is Safe and Works Better Than Rituximab Combined With Lenalidomide in Adult Participants With Follicular Lymphoma and Marginal Zone Lymphoma

Relapsed/Refractory Follicular LymphomaRelapsed/Refractory Marginal Zone Lymphoma (R/R MZL)
Regeneron Pharmaceuticals470 enrolled169 locationsNCT06149286
Recruiting
Phase 2

Safety and Efficacy Study of PF-06835375 in Primary Immune Thrombocytopenia

Primary immune thrombocytopenia
Pfizer91 enrolled16 locationsNCT05070845
Recruiting
Phase 3

Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Previously Untreated Follicular Lymphoma

Follicular Lymphoma ( FL)
Genmab1,095 enrolled266 locationsNCT06191744
Recruiting
Phase 3

This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.

Prostate CancerCancer of the ProstateHormone Sensitive Prostate Cancer+1 more
Pfizer1,000 enrolled300 locationsNCT07028853
Recruiting
Phase 3

A Study of Navenibart in Participants With Hereditary Angioedema

Hereditary Angioedema (HAE)
Astria Therapeutics, Inc.145 enrolled87 locationsNCT06842823
Recruiting
Phase 3

A Study to Learn About a Clostridioides Difficile Vaccine in People 65 Years of Age and Older

Clostridioides Difficile Associated Disease
Pfizer32,000 enrolled158 locationsNCT07282665
Recruiting
Phase 3

A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than 12 Years of Age With Moderate to Severe Atopic Dermatitis

Atopic Dermatitis
AbbVie675 enrolled148 locationsNCT06461897
Recruiting
Phase 3

A Trial to Learn if Odronextamab is Safe and Well-Tolerated and How Well it Works Compared to Rituximab Combined With Different Types of Chemotherapy for Adult Participants With Previously Untreated Follicular Lymphoma

Follicular Lymphoma ( FL)
Regeneron Pharmaceuticals822 enrolled190 locationsNCT06091254
Recruiting
Not Applicable

RCT of Implantable Defibrillators in Patients With Non Ischemic Cardiomyopathy, Scar and Severe Systolic Heart Failure

Heart Failure
University Hospital Southampton NHS Foundation Trust2,504 enrolled47 locationsNCT05568069
Recruiting
Not Applicable

Virtual Group Prehabilitation Education (Surgery School) Feasibility Trial

Elective surgeryPrehabilitationCancer Surgery+1 more
University Hospital Southampton NHS Foundation Trust24 enrolled1 locationNCT07278622
Recruiting

Splenic Embolisation Decisions

TraumaSpleen Injury
University Hospital Plymouth NHS Trust8,000 enrolled1 locationNCT06334263
Recruiting

Diabetes in Primary Care - Improving Classification

Diabetes Mellitus
University of Exeter45 enrolled9 locationsNCT06711718
Recruiting
Not Applicable

The Effect of Chlorhexidine Mouthwash on Postprandial Glucose Response in Healthy Individuals

Glucose Metabolism Disorders (Including Diabetes Mellitus)
University of Plymouth45 enrolled1 locationNCT07172009
Recruiting
Not Applicable

Pragmatic Randomised Trial of High Or Standard PHosphAte Targets in End-stage Kidney Disease (PHOSPHATE)

Kidney Failure, ChronicHyperphosphatemia
The University of Queensland3,600 enrolled115 locationsNCT03573089
Recruiting

Tolerance in Beekeepers

Bee Sting
University Hospital Plymouth NHS Trust120 enrolled1 locationNCT06156046
Recruiting
Phase 3

Timing to Restart Direct Oral Anticoagulants After Traumatic Intracranial Haemorrhage

Traumatic Intracranial Haemorrhage
Walton Centre NHS Foundation Trust1,084 enrolled2 locationsNCT06322953