Clinical Trials in Sheffield, England

13 recruiting

Showing 112 of 12 trials

Recruiting
Phase 3

A Study to Learn More About How Risankizumab Works in Young Participants With Ulcerative Colitis

Ulcerative Colitis
AbbVie120 enrolled40 locationsNCT07071519
Recruiting
Phase 3

Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors

Germ Cell TumorChildhood Extracranial Germ Cell TumorExtragonadal Embryonal Carcinoma+27 more
Children's Oncology Group1,780 enrolled629 locationsNCT03067181
Recruiting
Phase 3

Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

Solid TumorsHematologic Malignancies
Merck Sharp & Dohme LLC3,500 enrolled779 locationsNCT03486873
Recruiting
Phase 3

This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.

Non-small Cell Lung CancerCarcinoma, Non-Small Cell LungCarcinoma, Non-Small-Cell Lung (NSCLC)
Pfizer714 enrolled329 locationsNCT06758401
Recruiting
Phase 3

Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn's Disease

Crohn's Disease
AbbVie110 enrolled83 locationsNCT06332534
Recruiting
Not Applicable

Development of Novel Physiological CMR Methods in Health and Disease

Heart FailurePulmonary HypertensionMyocardial Infarction+1 more
Sheffield Teaching Hospitals NHS Foundation Trust135 enrolled1 locationNCT03854071
Recruiting
Phase 3

A Study to Assess Adverse Events, Change in Disease Activity, and How Intravenous and Subcutaneous Risankizumab Moves Through the Body of Pediatric Participants With Moderately to Severely Active Crohn's Disease

Crohn's Disease
AbbVie110 enrolled85 locationsNCT05995353
Recruiting
Phase 3

A Study to Assess Adverse Events, Change in Disease Activity, and How the Drug Moves Through the Body in Children With Juvenile Psoriatic Arthritis (jPsA) Receiving Subcutaneously Injected Risankizumab or Adalimumab

Juvenile Psoriatic Arthritis
AbbVie40 enrolled31 locationsNCT06100744
Recruiting

Prospective Clinical Assessment Study in Children With Hypochondroplasia

Hypochondroplasia
QED Therapeutics, a BridgeBio company150 enrolled25 locationsNCT06410976
Recruiting
Phase 3

Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia

Community-acquired Pneumonia, Influenza, COVID-19
UMC Utrecht20,000 enrolled408 locationsNCT02735707
Recruiting
Not Applicable

Use of PET-MR in Head and Neck Cancer Patients - Diagnostic and Therapeutic Applications

Head and Neck Cancer
Sheffield Teaching Hospitals NHS Foundation Trust10 enrolled1 locationNCT06032663
Recruiting

Biomarkers of aHSCT

Multiple Sclerosis, Relapsing-Remitting
Sheffield Teaching Hospitals NHS Foundation Trust15 enrolled1 locationNCT06195800