Towards better assessment and treatment of exercise induced wheeze
Comprehensive assessment of patients with exercise induced wheeze using pulmonary function testing, bronchial challenge testing (methacholine and Mannitol) and exhaled nitric oxide. A comparison of either inhaled steroids or a cross-over study of cromoglycate, montelukast and formoterol
University of Otago
60 participants
Nov 1, 2005
Interventional
Conditions
Summary
Exercise induced symptoms are common especially in patients with asthma. There are several possible treatments for exercise induced wheeze. This study aims to provide further evidence to help GPs decide on which treatment is best for an individual patient
Eligibility
Inclusion Criteria1
- Exercise induced wheeze, cough or dyspnoea are the primary symptoms.
Exclusion Criteria1
- Current or recent ex-smokers, patients taking oral or inhaled steroids in the previous 6 weeks.
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Interventions
Following comprehensive assessment, patients with exercise induced symptoms will be divided into two groups according to their baseline exhaled nitric oxide levels (FeNO). Those with a high FeNO (>35ppb) will receive inhaled fluticasone for 6 weeks.
Locations(1)
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ACTRN12605000397617