RecruitingNCT07399665

ReAl-woRld Evaluation of tEzepelumab for Chronic rhinoSinusitis With Nasal Polyps in Russia

Open-label Single-arm, Non-interventional, Multi-centre Study for Evaluation of Clinical and Patient Reported Outcomes in Adult Patients With CRSwNP on Tezepelumab


Sponsor

AstraZeneca

Enrollment

110 participants

Start Date

Dec 25, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

ARES is a multi-centre, retrospective-prospective, non-comparative and non-interventional (observational) cohort study involving primary and secondary data collection within real-world settings of participants who have initiated tezepelumab (no more than 4 weeks before inclusion) for treatment of CRSwNP (with or without comorbid asthma).


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This real-world observational study is tracking how well tezepelumab — a biologic injection that blocks an inflammatory protein called TSLP — works in Russian patients with chronic sinusitis with nasal polyps (CRSwNP), a condition causing persistent blocked nose, reduced sense of smell, and often requiring repeated surgery. The study will compare patients' health before and after starting the drug. **You may be eligible if...** - You are 18 or older - You have been diagnosed with chronic sinusitis with nasal polyps for at least 52 weeks - Your doctor has already prescribed tezepelumab for your condition - Your medical records cover at least the past year **You may NOT be eligible if...** - You have not been prescribed tezepelumab, or it was prescribed but not yet started - You are enrolled in another interventional clinical trial at the same time - Your past medical records are insufficient for the study's requirements Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(9)

Research Site

Kazan', Russia

Research Site

Krasnoyarsk, Russia

Research Site

Moscow, Russia

Research Site

Rostov-on-Don, Russia

Research Site

Ryazan, Russia

Research Site

Saint-Petesburg, Russia

Research Site

Saint-Petesburg, Russia

Research Site

Ulyanovsk, Russia

Research Site

Yekaterinburg, Russia

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NCT07399665


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