CompletedPhase 2ACTRN12610000743066

Reduction of Surgical Site Infection in Cardiac Surgery using a Microbial Sealant-A Controlled Study

In coronary artery bypass patients requiring greater than 2 lengths of saphenous vein for conduit does the application of a cyanoacrylate surgical sealant prior to leg wound incision decrease wound infection rates scored at 1 month when compared to the contralateral leg wound in the same patient.

Sponsor

Ian Gilfillan

Enrollment

100 participants

Start Date

Jul 14, 2008

Study Type

Interventional

Conditions

Surgical Site Infection

Summary

A trial to see if the use of a cyanoacrylate ("Superglue") sealant applied to the skin prior to the surgical incsion can reduce the incidence of post operative wound infections.

Eligibility

Sex: Both males and femalesMin Age: 40 YearssMax Age: 90 Yearss

Plain Language Summary

Simplified for easier understanding

This study tests whether applying a microbial skin sealant before heart bypass surgery can reduce surgical wound infections in the leg where the vein graft is taken. You must be aged 40 to 90 and undergoing coronary artery bypass surgery requiring more than 2 lengths of leg vein. People with peripheral vascular disease, leg skin lesions, or allergies to cyanoacrylate products cannot participate.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

Application of a cyanoacrylate microbial surgical sealant to the skin surface immediately prior to skin incision for removal of the long saphenous vein for coronary artery bypass surgery. Applied di

Application of a cyanoacrylate microbial surgical sealant to the skin surface immediately prior to skin incision for removal of the long saphenous vein for coronary artery bypass surgery. Applied directly from sterile container with sponge applicator. Probable mechanism of action is the fixation of microorganisms within hair follicles and sweat glands, thus reducing quantitatively the contamination of the incision.